BDB611562

Hsp60 Mouse, Unlabeled, Clone: 24/HSP60, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611562-Each-of-1 In Stock ₹ 24,085.14

BDB611562 - Each of 1

₹ 24,085.14

In Stock

Quantity

1

Base Price: ₹ 24,085.14

GST (18%): ₹ 4,335.325

Total Price: ₹ 28,420.465

Antigen

Hsp60

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Human Hsp60 aa. 1-200

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

24/HSP60

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Heat shock proteins (Hsp) are a set of highly conserved proteins that include constitutively expressed (Hsp60, Hsp70, and Hsp90) and stress-induced (Hsp27 and Hsp72) proteins
  • Hsp60 is localized to the mitochondria, where it promotes mitochondrial protein folding and facilitates proteolytic degradation of misfolded or denatured proteins
  • It binds Hsp10, which regulates the substrate binding and ATPase activity of Hsp60
  • In HeLa and Jurkat mitochondria, Hsp60 associates with caspase-3 to form a complex that dissociates and releases from the mitochondria during apoptosis
  • In addition, Hsp60 accelerates the maturation of procaspase-3 through its ATP-dependent “foldase” activity
  • In addition to its role in protein folding, Hsp60 has also been implicated in immune function
  • In macrophages, its binding to the toll-like receptor-4 complex induces production of TNFα and nitric oxide and stimulation of a proinflammatory response
  • Thus, the protein folding function of Hsp60 is involved in mitochondrial protein folding in both normal and apoptotic cells, while release of Hsp60 during necrosis is thought to stimulate a proinflammatory response
  • Host Species: Mouse Clone: 24 Isotype: IgG1 Species Reactivity: Human Immunogen: Human Hsp60 aa
  • 1-200 Formula Weight [Chemical]: 60kDa Immunofluorescence, Western Blotting

Compare Similar Items

Show Difference

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Fischer Scientific

BDB611562

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Antigen:
Hsp60

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Hsp60 aa. 1-200

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
24/HSP60

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

Img

Fischer Scientific

BDB611563

--


Antigen:
Hsp60

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Human Hsp60 aa. 1-200

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
24/HSP60

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Chk2

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse Chk2 aa. 31-234

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
19

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
Intersectin/ESE-1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse Ese-1 aa. 800-909

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Chicken, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
29

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.