BDB611563
Hsp60 Mouse, Unlabeled, Clone: 24/HSP60, BD
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB611563-Each-of-1 | In Stock | ₹ 47,571.36 |
BDB611563 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,571.36
GST (18%): ₹ 8,562.845
Total Price: ₹ 56,134.205
Antigen
Hsp60
Classification
Monoclonal
Concentration
250μg/mL
Formulation
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen
Human Hsp60 aa. 1-200
Quantity
150 μg
Research Discipline
Cell Biology
Target Species
Human, Mouse, Rat
Isotype
IgG1
Applications
Western Blot
Clone
24/HSP60
Conjugate
Unconjugated
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Store undiluted at -20°C.
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Description
- Heat shock proteins (Hsp) are a set of highly conserved proteins that include constitutively expressed (Hsp60, Hsp70, and Hsp90) and stress-induced (Hsp27 and Hsp72) proteins
- Hsp60 is localized to the mitochondria, where it promotes mitochondrial protein folding and facilitates proteolytic degradation of misfolded or denatured proteins
- It binds Hsp10, which regulates the substrate binding and ATPase activity of Hsp60
- In HeLa and Jurkat mitochondria, Hsp60 associates with caspase-3 to form a complex that dissociates and releases from the mitochondria during apoptosis
- In addition, Hsp60 accelerates the maturation of procaspase-3 through its ATP-dependent “foldase” activity
- In addition to its role in protein folding, Hsp60 has also been implicated in immune function
- In macrophages, its binding to the toll-like receptor-4 complex induces production of TNFα and nitric oxide and stimulation of a proinflammatory response
- Thus, the protein folding function of Hsp60 is involved in mitochondrial protein folding in both normal and apoptotic cells, while release of Hsp60 during necrosis is thought to stimulate a proinflammatory response
- Host Species: Mouse Clone: 24 Isotype: IgG1 Species Reactivity: Human Immunogen: Human Hsp60 aa
- 1-200 Formula Weight [Chemical]: 60kDa Immunofluorescence, Western Blotting
Compare Similar Items
Show Difference
Antigen: Hsp60
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human Hsp60 aa. 1-200
Quantity: 150 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 24/HSP60
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Hsp60
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human Hsp60 aa. 1-200
Quantity:
150 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
24/HSP60
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Chk2
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse Chk2 aa. 31-234
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 19
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Chk2
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse Chk2 aa. 31-234
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
19
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: Intersectin/ESE-1
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Mouse Ese-1 aa. 800-909
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Chicken, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 29
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
Intersectin/ESE-1
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Mouse Ese-1 aa. 800-909
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Chicken, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
29
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.
Antigen: TAP
Classification: Monoclonal
Concentration: 250μg/mL
Formulation: Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen: Human TAP aa. 488-596
Quantity: 50 μg
Research Discipline: Cell Biology
Target Species: Canine, Human, Mouse, Rat
Isotype: IgG1
Applications: Western Blot
Clone: 19
Conjugate: Unconjugated
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Store undiluted at -20°C.
Antigen:
TAP
Classification:
Monoclonal
Concentration:
250μg/mL
Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.
Immunogen:
Human TAP aa. 488-596
Quantity:
50 μg
Research Discipline:
Cell Biology
Target Species:
Canine, Human, Mouse, Rat
Isotype:
IgG1
Applications:
Western Blot
Clone:
19
Conjugate:
Unconjugated
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at -20°C.