BDB611880

Synaptophysin Mouse, Unlabeled, Clone: 2, BD

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611880-Each-of-1 In Stock ₹ 24,598.50

BDB611880 - Each of 1

₹ 24,598.50

In Stock

Quantity

1

Base Price: ₹ 24,598.50

GST (18%): ₹ 4,427.73

Total Price: ₹ 29,026.23

Antigen

Synaptophysin

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Rat Synaptophysin aa. 205-306

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Human, Mouse, Rat

Isotype

IgG1

Applications

Western Blot

Clone

2

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • Synaptophysin is a major integral membrane glycoprotein that was isolated from the presynaptic vesicles of neurons
  • The structure of synaptophysin includes four transmembrane domains (TMD), an N-temrinal glycosylation site, nine repeats of basic tetrapeptide motifs (GYGP), multiple collagenase sensitive sites (XGP), and several collagen-type tripeptides (GXX)
  • Synaptophysin mRNA is expressed in nervous tissues, as well as many neuroendocrine tumor cell lines
  • In PC12 cells and brain synaptic vesicles, synaptophysin binds cholesterol, and cholesterol depletion blocks the biogenesis of synaptic-like microvesicles
  • In addition, synaptophysin binds dynamin in a Ca 2 + -dependent manner, and injection of peptides that disrupt this interaction decreases neurotransmitter release during high-frequency stimulation of squid neurons
  • This decrease in neurotransmitter release results from inhibition of synaptophysin-dependent vesicle retrieval
  • Thus, synaptophysin may have important roles in the biogenesis and recycling of synaptic vesicles
  • Synaptophysin is an integral membrane glycoprotein with a calculated molecular weight of 33kD, but has been reported to be observed at 38-42kD due to glycosylation
  • Host Species: Mouse Clone: 2 Isotype: IgG1 Species Reactivity [for Features Main]: Rat Immunogen: Rat Synaptophysin aa
  • 205-306 Western Blotting

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BDB611880

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Antigen:
Synaptophysin

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Rat Synaptophysin aa. 205-306

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
2

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
COMT

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse COMT aa. 26-141

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
4

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
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Concentration:
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Immunogen:
Mouse TRE1 aa. 82-179

Quantity:
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Research Discipline:
Cell Biology

Target Species:
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Isotype:
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Applications:
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Clone:
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Conjugate:
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Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
TREX1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse TRE1 aa. 82-179

Quantity:
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Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
29

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.