BDB611986

TREX1 Mouse anti-Mouse, Unlabeled, Clone: 29, BD

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB611986-Each-of-1 In Stock ₹ 24,470.16

BDB611986 - Each of 1

₹ 24,470.16

In Stock

Quantity

1

Base Price: ₹ 24,470.16

GST (18%): ₹ 4,404.629

Total Price: ₹ 28,874.789

Antigen

TREX1

Classification

Monoclonal

Concentration

250μg/mL

Formulation

Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen

Mouse TRE1 aa. 82-179

Quantity

50 μg

Research Discipline

Cell Biology

Target Species

Mouse

Isotype

IgG1

Applications

Western Blot

Clone

29

Conjugate

Unconjugated

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Store undiluted at -20°C.

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Description

  • DNA replication, repair, and recombination requires the excision of nucleotides from the DNA 3′ termini
  • Many 3′ to 5′ exonucleases have been identified which catalyze the excision of monophosphates from the 3′ termini of DNA
  • TREX1 and TREX2 are 3′ to 5′ exonucleases that contain three conserved exonuclease active site motifs (EASM) that may produce exonuclease activity
  • TREX1 and TREX2 are most closely related to the proofreading exonucleases of the bacterial replicative DNA polymerases and the RNase T enzymes
  • Recombinant expression of TREX1 and TREX2 demonstrates that they have exonuclease activity when oligonucleotide is present
  • TREX1 shows the greatest exonuclease activity with partial duplex DNA, and no activity with single-stranded RNA or an RNA-DNA partial duplex
  • In addition, reconstitution of TREX1 with DNA polymerase β and DNA ligase III-XRCC1 facilitates accurate rejoining of a 3′ mismatched base residue at a single-strand break
  • Thus, TREX1 and TREX2 are 3′ to 5′ exonucleases that may be important for excision of nucleotides during DNA replication, repair, and recombination
  • Host Species: Mouse Clone: 29 Isotype: IgG1 Species Reactivity [for Features Main]: Human Immunogen: Mouse TRE1 aa
  • 82-179 Immunofluorescence, Western Blotting

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Fischer Scientific

BDB611986

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Antigen:
TREX1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse TRE1 aa. 82-179

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
29

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Antigen:
TREX1

Classification:
Monoclonal

Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse TRE1 aa. 82-179

Quantity:
150 μg

Research Discipline:
Cell Biology

Target Species:
Mouse

Isotype:
IgG1

Applications:
Western Blot

Clone:
29

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse MTP aa. 91-288

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Mouse, Rat

Isotype:
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Applications:
Western Blot

Clone:
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Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.

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CtBP1 (C-terminal Binding Protein-1)

Classification:
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Concentration:
250μg/mL

Formulation:
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide.

Immunogen:
Mouse CtBP1 aa. 345-441

Quantity:
50 μg

Research Discipline:
Cell Biology

Target Species:
Canine, Chicken, Human, Mouse, Rat

Isotype:
IgG1

Applications:
Western Blot

Clone:
3

Conjugate:
Unconjugated

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at -20°C.