CD79b Mouse anti-Human, Brilliant Violet 786, Clone: CB3-1, BD Optibuild™

Description

• Immunoglobulin (Ig) antigen receptors are composed of a non-covalently-associated complex of Ig and two other proteins, Igαand Igβ, which have been designated in the Fifth International Leukocyte Workshop as CD79a and CD79b respectively
• The CB3-1 monoclonal antibody specifically binds to CD79b, which is expressed on surface Ig (sIg)-positive lymphocytes and B-cell lines but only in the cytoplasm of sIg-negative cells including most terminal deoxynucleotidyl transferase (TdT) positive early pre-B and all cytoplasmic μ positive pre-B cell lines
• Antibodies to CD79b are helpful in delineating signal transduction pathways activated via antibody receptors during different stages of B-cell differentiation The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
• This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
• BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
• BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
• BV786 offers a bright choice for the 6th detector off the violet laser.