BDB743598

CXCR6 (CD186) Mouse anti-Human, Brilliant Violet 510, Clone: 13B 1E5, BD Optibuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB743598-Each-of-1 In Stock ₹ 47,400.24

BDB743598 - Each of 1

₹ 47,400.24

In Stock

Quantity

1

Base Price: ₹ 47,400.24

GST (18%): ₹ 8,532.043

Total Price: ₹ 55,932.283

Antigen

CXCR6 (CD186)

Clone

13B 1E5

Conjugate

Brilliant Violet 510

Gene Alias

C-X-C chemokine receptor type 6, BONZO, STRL33, TYMSTR

Immunogen

Human CXCR6

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification

Monoclonal

Concentration

0.2mg/mL

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species

Mouse

Purification Method

Affinity Purified

Regulatory Status

RUO

Target Species

Human

Isotype

IgG2a κ

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Description

  • The 13B 1E5 monoclonal antibody specifically binds to C-X-C chemokine receptor type 6 (CXCR6), which is also known as CD186, BONZO, T-lymphocyte-expressed seven-transmembrane domain receptor (TYMSTR), and Seven transmembrane receptor-like from clone 33 (STRL33)
  • CXCR6 is a G-protein coupled chemokine receptor that is expressed on subsets of activated and memory T cells and NKT cells
  • CXCR6 binds to soluble CXCL16 and membrane-anchored CXCL16 expressed by dendritic cells and macrophages
  • The CXCL16 and CXCR6 interaction activates Akt and mTor signaling
  • This regulates cellular migration including the recruitment of tumor-infiltrating lymphocytes and may contribute to the progression and metastasis of various cancers
  • CXCR6 also can serve as a coreceptor for certain strains of HIV-1 and HIV-2
  • The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes
  • With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set
  • BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser
  • BV510 is a polymer-based dye that is brighter than BD Horizon V500
  • Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.

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BD Biosciences

BDB743598

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Antigen:
CXCR6 (CD186)

Clone:
13B 1E5

Conjugate:
Brilliant Violet 510

Gene Alias:
C-X-C chemokine receptor type 6, BONZO, STRL33, TYMSTR

Immunogen:
Human CXCR6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB743602

--


Antigen:
CXCR6 (CD186)

Clone:
13B 1E5

Conjugate:
Brilliant Violet 786

Gene Alias:
C-X-C chemokine receptor type 6, BONZO, STRL33, TYMSTR

Immunogen:
Human CXCR6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

Img

BD Biosciences

BDB743603

--


Antigen:
CXCR6 (CD186)

Clone:
13B 1E5

Conjugate:
Brilliant Ultraviolet 395

Gene Alias:
C-X-C chemokine receptor type 6, BONZO, STRL33, TYMSTR

Immunogen:
Human CXCR6

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG2a κ

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BD Biosciences

BDB743605

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Antigen:
CD1d

Clone:
CD1d42 (also known as 42.1)

Conjugate:
Brilliant Violet 605

Gene Alias:
R3, R3G1, HMC class I antigen-like glycoprotein CD1D

Immunogen:
Human CD1d Recombinant Protein

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Classification:
Monoclonal

Concentration:
0.2mg/mL

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Host Species:
Mouse

Purification Method:
Affinity Purified

Regulatory Status:
RUO

Target Species:
Human

Isotype:
IgG1 κ