BDB743963
TSLP Receptor Mouse anti-Human, Brilliant Violet 786, Clone: 1F11/TSLPR (1F11 and AB81_85.1F11), BD Optibuild™
Manufacturer: BD Biosciences
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB743963-Each-of-1 | In Stock | ₹ 47,400.24 |
BDB743963 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,400.24
GST (18%): ₹ 8,532.043
Total Price: ₹ 55,932.283
Antigen
TSLP Receptor
Clone
1F11/TSLPR (also known as 1F11 and AB81_85.1F11)
Conjugate
Brilliant Violet 786
Gene Alias
CRL2, CRLF2, CRLF2Y, Cytokine receptor-like factor 2, IL-XR, TSLPR
Immunogen
Human TSLP Receptor Transfected Cell Line
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification
Monoclonal
Concentration
0.2mg/mL
Formulation
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species
Mouse
Purification Method
Affinity Purified
Regulatory Status
RUO
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- The 1F11/TSLPR mAb specifically binds to Thymic Stromal Lymphopoietin Receptor (TSLPR)
- TSLPR is a member of the hematopoietin receptor superfamily and is also known as Cytokine Receptor-like Factor 2
- The functional TSLPR complex consists of two subunits, TSLPR and the alpha subunit of the Interleukin-7 Receptor (IL-7Rα)
- Analysis of the TSLPR reveals sequence similarity with the common cytokine receptor gamma chain
- Functional TSLPRs are expressed by epithelial cells and a variety of hematopoietic cell types, including thymocytes, T cells, B cells, natural killer T cells, monocytes, macrophages, basophils, and dendritic cells (DC)
- Recent studies indicate that TSLP can activate multiple STAT signaling proteins
- TSLP enhances the maturation and viability of DC
- It strongly induces DC expression of the CD40 and CD80 costimulatory molecules and chemokines, e.g., TARC (Thymus and activation-regulated chemokine; CCL17) that can attract Th2 effector cells
- TSLP supports B cell development
- TSLP costimulates the proliferation of naοve T cells in the presence of mature DC
- TSLP is also able to increase the sensitivity of T cell receptor-activated CD4+ T cells to low doses of IL-2
- In the presence of TSLP, the acute myeloid leukemia-derived cell line, MUTZ-3, shows induced growth and reduced apoptosis
- CRLF2 deregulated gene expression is thought to be involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
- The antibody was conjugated to BD Horizon™ BV786 which is part of the BD Horizon Brilliant™ Violet family of dyes
- This dye is a tandem fluorochrome of BD Horizon BV421 with an Ex Max of 405nm and an acceptor dye with an Em Max at 786nm
- BD Horizon BV786 can be excited by the violet laser and detected in a filter used to detect Cy™7-like dyes (eg, 780/60nm filter)
- BV786 is a tandem fluorochrome of BD Horizon BV421 and an acceptor dye with an emission maximum at 786 nm
- BV786 offers a bright choice for the 6th detector off the violet laser.
Compare Similar Items
Show Difference
Antigen: TSLP Receptor
Clone: 1F11/TSLPR (also known as 1F11 and AB81_85.1F11)
Conjugate: Brilliant Violet 786
Gene Alias: CRL2, CRLF2, CRLF2Y, Cytokine receptor-like factor 2, IL-XR, TSLPR
Immunogen: Human TSLP Receptor Transfected Cell Line
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
TSLP Receptor
Clone:
1F11/TSLPR (also known as 1F11 and AB81_85.1F11)
Conjugate:
Brilliant Violet 786
Gene Alias:
CRL2, CRLF2, CRLF2Y, Cytokine receptor-like factor 2, IL-XR, TSLPR
Immunogen:
Human TSLP Receptor Transfected Cell Line
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ
Antigen: Lgr5
Clone: 4D11F8 (also known as 4D11)
Conjugate: Brilliant Violet 510
Gene Alias: LGR5, FEX, HG38, GPR49, GPR67, GRP49
Immunogen: Human LGR5 DNA
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b λ
Antigen:
Lgr5
Clone:
4D11F8 (also known as 4D11)
Conjugate:
Brilliant Violet 510
Gene Alias:
LGR5, FEX, HG38, GPR49, GPR67, GRP49
Immunogen:
Human LGR5 DNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b λ
Antigen: Lgr5
Clone: 4D11F8 (also known as 4D11)
Conjugate: Brilliant Violet 786
Gene Alias: LGR5, FEX, HG38, GPR49, GPR67, GRP49
Immunogen: Human LGR5 DNA
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Rat
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG2b λ
Antigen:
Lgr5
Clone:
4D11F8 (also known as 4D11)
Conjugate:
Brilliant Violet 786
Gene Alias:
LGR5, FEX, HG38, GPR49, GPR67, GRP49
Immunogen:
Human LGR5 DNA
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Rat
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG2b λ
Antigen: Light Chain, λ
Clone: JDC-12
Conjugate: Brilliant Violet 650
Gene Alias: Ig λ, IGL@, IGL, Immunoglobulin lambda locus
Immunogen: __
Quantity: 50 μg
Primary or Secondary: Primary
Content And Storage: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification: Monoclonal
Concentration: 0.2mg/mL
Formulation: Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species: Mouse
Purification Method: Affinity Purified
Regulatory Status: RUO
Target Species: Human
Isotype: IgG1 κ
Antigen:
Light Chain, λ
Clone:
JDC-12
Conjugate:
Brilliant Violet 650
Gene Alias:
Ig λ, IGL@, IGL, Immunoglobulin lambda locus
Immunogen:
__
Quantity:
50 μg
Primary or Secondary:
Primary
Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Classification:
Monoclonal
Concentration:
0.2mg/mL
Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.
Host Species:
Mouse
Purification Method:
Affinity Purified
Regulatory Status:
RUO
Target Species:
Human
Isotype:
IgG1 κ