BDB751905

TCR VA7.2 Mouse, anti-Human, R718, Clone: OF-5A12, BD OptiBuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB751905-Each-of-1 In Stock ₹ 35,421.84

BDB751905 - Each of 1

₹ 35,421.84

In Stock

Quantity

1

Base Price: ₹ 35,421.84

GST (18%): ₹ 6,375.931

Total Price: ₹ 41,797.771

Antigen

TCR VA7.2

Classification

Monoclonal

Conjugate

R718

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Refrigerate Upon Arrival

Applications

Flow Cytometry

Clone

OF-5A12

Host Species

Mouse

Regulatory Status

RUO

Target Species

Human

Form

Liquid

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Description

  • Description The OF-5A12 monoclonal antibody specifically recognizes the human variable alpha 7.2 region of the T cell receptor for antigen (TCR Vα7.2) that is joined with the Jα33 segment to form an invariant TCR which is characteristically expressed by mucosal-associated invariant T cells (MAIT cells)
  • MAIT cell recognition of antigen is restricted by MHC-related molecule 1 (MR1), a nonpolymorphic Class Ib Major Histocompatibility Complex (MHC) molecule, that associates with β2-microglobulin
  • MAIT cells are found in human peripheral blood, mesenteric lymph nodes, liver, and mucosa associated with the lungs and intestines
  • MAIT cells play a role in detecting and fighting off microbial infections
  • The specificity of OF-5A12 for the TCR Vα7.2 was confirmed by its ability to block the binding of another human TCR Vα7.2-specific antibody, 3C10, to MAIT cells.

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Antigen:
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Classification:
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Conjugate:
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Quantity:
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Primary or Secondary:
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Content And Storage:
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