CD97 Mouse, anti-Human, R718, Clone: VIM3B, BD OptiBuild™

Description

• The VIM3b monoclonal antibody recognizes CD97
• CD97 is a seven-span transmembrane protein that belongs to the G-protein coupled receptor superfamily
• CD97 is encoded by ADGRE5 (adhesion G protein-coupled receptor E5)
• CD97 is highly expressed on monocytes and granulocytes
• It is also expressed on dendritic cells, T cells, B cells, NK cells, and smooth muscle cells
• CD97 expression is upregulated on activated T cells
• CD97 is also expressed on several cell lines including HL-60, THP-1, and K562
• CD97 reportedly plays roles in leucocyte signaling, adhesion, and migration
• The VIM3b antibody works in Western blotting and immunoprecipitation
• The antibody recognizes proteins of 74, 80 and 89 kDa
• CD55 and chondroitin sulfate are ligands for CD97.