BDB751907

ROR1 Mouse, anti-Human, R718, Clone: 4A5, BD OptiBuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB751907-Each-of-1 In Stock ₹ 35,421.84

BDB751907 - Each of 1

₹ 35,421.84

In Stock

Quantity

1

Base Price: ₹ 35,421.84

GST (18%): ₹ 6,375.931

Total Price: ₹ 41,797.771

Antigen

ROR1

Classification

Monoclonal

Conjugate

R718

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Refrigerate Upon Arrival

Applications

Flow Cytometry

Clone

4A5

Host Species

Mouse

Regulatory Status

RUO

Target Species

Human

Form

Liquid

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Description

  • The 4A5 monoclonal antibody binds to the glycosylated type I membrane protein ROR1 (Receptor-tyrosine-kinase-like Orphan Receptor 1)
  • The ROR1 and ROR2 related proteins are highly conserved evolutionarily and are primarily expressed during embryogenesis
  • ROR1 is not expressed on normal peripheral blood lymphocytes
  • ROR1 is similar to tropomyosin receptor kinase (Trk family) neurotropic receptors and shares a cysteine-rich domain with Frizzled receptors for Wnt-family signaling proteins, which are involved in the regulation of embryogenesis and carcinogenesis
  • Furthermore, there is mounting evidence that aberrant ROR1 expression contributes to human malignancy.

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