BDB751977
CD49e Mouse, anti-Mouse, R718, Clone: HM α 5-1, BD OptiBuild™
Manufacturer: BD Biosciences
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | BDB751977-Each-of-1 | In Stock | ₹ 27,379.20 |
BDB751977 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 27,379.20
GST (18%): ₹ 4,928.256
Total Price: ₹ 32,307.456
Antigen
CD49e
Classification
Monoclonal
Conjugate
R718
Quantity
50 μg
Primary or Secondary
Primary
Content And Storage
Refrigerate Upon Arrival
Applications
Flow Cytometry
Clone
HM α 5-1
Host Species
Mouse
Regulatory Status
RUO
Target Species
Mouse
Form
Liquid
Related Products
Description
- Description The HMα5-1 antibody specifically recognizes the α5 subunit of the integrin α5β1 fibronectin receptor (CD49e/CD29, VLA-5) on mouse thymocytes and a variety of mouse cell lines, including pre-B and non-lymphoid cells, but not on mouse splenic or lymph node cells
- It also detects rat CD49e on the RBL2H3 basophilic leukemia cell line,peritoneal mast cells, and endothelium, but not on splenocytes
- It has been reported that soluble mAb HMα5-1 partially inhibits in vitro binding of a mouse cell line and of rat mast cells to fibronectin and inhibits the enhanced degranulation of IgE-sensitized rat RBL cells induced on fibronectin-coated plates
- It has also been observed that plate-bound HMα5-1 antibody enhances the degranulation of IgEsensitized rat RBL-2H3 cells and that subcutaneous injection of HMα5-1 mAb into rats, along with anti-CD49d and anti-CD61 antibodies, inhibits experimentally induced passive cutaneous anaphylaxis.
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