BDB752373

CD45RB Mouse, anti-Mouse, R718, Clone: 16A, BD OptiBuild™

Manufacturer: BD Biosciences

Select a Size

Pack Size SKU Availability Price
Each of 1 BDB752373-Each-of-1 In Stock ₹ 27,379.20

BDB752373 - Each of 1

₹ 27,379.20

In Stock

Quantity

1

Base Price: ₹ 27,379.20

GST (18%): ₹ 4,928.256

Total Price: ₹ 32,307.456

Antigen

CD45RB

Classification

Monoclonal

Conjugate

R718

Quantity

50 μg

Primary or Secondary

Primary

Content And Storage

Refrigerate Upon Arrival

Applications

Flow Cytometry

Clone

16A

Host Species

Mouse

Regulatory Status

RUO

Target Species

Mouse

Form

Liquid

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Description

  • The 16A monoclonal antibody specifically recognizes an exon B-dependent epitope of CD45 lycoprotein, which is found at high density on peripheral B cells, T cytotoxic/suppressor cells, a subset of T helper cells, and most thymocytes, and at low density on macrophages and dendritic cells
  • CD45RB expression appears to decrease as T lymphocytes progress from naive to memory cells
  • In addition, subpopulations of CD4+ T cells which express high and low levels of CD45RB have different cytokine secretion profiles and mediate distinct immunological functions
  • CD25+ D4+ regulatory T (Treg) lymphocytes which control intestinal inflammation and autoimmunity express low levels of CD45RB
  • CD45 is a member of the Protein Tyrosine Phosphatase (PTP) family| its intracellular (COOH-terminal) region contains two PTP catalytic domains, and the extracellular region is highly variable due to alternative splicing of exons (designated A, B, and C, respectively) as well as differing levels of glycosylation
  • The CD45 isoforms detected in the mouse are cell type-, maturation-, and activation state-specific
  • The CD45 isoforms play complex roles in T-cell and B-cell antigen receptor signal transduction.

Compare Similar Items

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BD Biosciences

BDB752373

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Antigen:
CD45RB

Classification:
Monoclonal

Conjugate:
R718

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Refrigerate Upon Arrival

Applications:
Flow Cytometry

Clone:
16A

Host Species:
Mouse

Regulatory Status:
RUO

Target Species:
Mouse

Form:
Liquid

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BD Biosciences

BDB752374

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Antigen:
CX3CL1 (Fractalkine)

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Quantity:
1 x 50 μg

Primary or Secondary:
Primary

Content And Storage:
Refrigerate (2 to 8°C)

Applications:
Flow Cytometry

Clone:
V13-864

Host Species:
Mouse

Regulatory Status:
RUO

Target Species:
Human

Form:
__

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BD Biosciences

BDB752375

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Antigen:
Podoplanin

Classification:
Monoclonal

Conjugate:
R718

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Refrigerate Upon Arrival

Applications:
Flow Cytometry

Clone:
LPMAB-17

Host Species:
Mouse

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid

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BD Biosciences

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Antigen:
CD15

Classification:
Monoclonal

Conjugate:
Brilliant Violet 421

Quantity:
50 μg

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated to the dye under optimum conditions that minimize unconjugated dye and antibody.

Applications:
Flow Cytometry

Clone:
7C3.rMAb (also known as PMN7C3 or 7C3)

Host Species:
Mouse

Regulatory Status:
RUO

Target Species:
Human

Form:
Liquid