CBL171I

MilliporeSigma™ Mouse anti-Actin, smooth muscle, Clone: ASM-1 (1A4),

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 CBL171I-Each-of-1 In Stock ₹ 50,364.04

CBL171I - Each of 1

₹ 50,364.04

In Stock

Quantity

1

Base Price: ₹ 50,364.04

GST (18%): ₹ 9,065.527

Total Price: ₹ 59,429.567

Antigen

Actin, smooth muscle

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

ACTA2; AAT6; ACTSA; ACTVS; GIG46; MYMY5

Immunogen

BSA-conjugated linear peptide corresponding to the N-terminal sequence of human smooth muscle actin.

Quantity

100 μg

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_001604.1

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2a κ

Applications

ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone

ASM-1 (1A4)

Gene Accession No.

P62736

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Bovine, Chicken, Human, Mouse, Rat

Form

Purified

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Description

  • Specifically detects Actin, smooth muscle clone: ASM-1 (1A4) in Bovine, Chicken, Human, Mouse, Rat samples, and it is validated for ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blotting Actin, aortic smooth muscle (UniProt P62736; also known as Alpha-actin-2, Cell growth-inhibiting gene 46 protein) is encoded by the ACTA2 (also known as AAT6, ACTSA, ACTVS, GIG46, MYMY5) gene (Gene ID 59) in human
  • Actins are globular multi-functional proteins that serve as the basic building blocks of cytoskeletal microfilaments and are among the most conserved eukaryotic proteins
  • Six actin types exist, skeletal muscle alpha-actin is encoded by the ACTA1 gene, smooth muscle alpha-actin by the ACTA2 gene, cytoplasmic beta-actin by the ACTB gene, cardiac muscle alpha-actin by the ACTC1 gene, cytoplasmic gamma-actin by the ACTG1 gene, and smooth muscle gamma-actin by the ACTG2 (a.k.a
  • ACTA3) gene
  • Although actins show 90% overall sequence homology, isoforms do show spatial, temporal, and tissue-specific expresson patterns and only 50-60% homology is found in their 18 N-terminal residues
  • Cytoplasmic β and γ-actins, are thought to be present in all cells, while the other four actin isoforms are typically found in specific adult muscle tissue types
  • Actins exist in a variety of structural states, depending on the specific ionic conditions or the interaction with ligand proteins
  • The oligomeric and polymeric forms that actin molecules assume are dependent on the distinct conformations they adopt.

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MilliporeSigma™

CBL171I

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Antigen:
Actin, smooth muscle

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
ACTA2; AAT6; ACTSA; ACTVS; GIG46; MYMY5

Immunogen:
BSA-conjugated linear peptide corresponding to the N-terminal sequence of human smooth muscle actin.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_001604.1

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
ASM-1 (1A4)

Gene Accession No.:
P62736

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma

CBL171MI

--


Antigen:
Actin

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2a presented as lyophilized material. Reconstitute in 1 mL of of distilled water.Final solution is PBS, pH 7.4, containing 0.5% BSA and 0.09% sodium azide.

Gene Symbols:
ACTA2, ACTSA, AAT6

Immunogen:
Synthetic peptide corresponding to the ten N-terminal amino acids of the alpha-smooth muscle isoform of actin.

Quantity:
50 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG2a

Applications:
Immunofluorescence, Immunohistochemistry, Western Blot

Clone:
ASM-1

Gene Accession No.:
NP_001604

Host Species:
Mouse

Purification Method:
Protein A purfied

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Equine, Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma

CBL173MI

--


Antigen:
Desmoplakin 1&2

Classification:
Monoclonal

Formulation:
Lyophilized. Reconstitute in 1 mL distilled water (final solution contains 0.09% sodiumazide, 0.5% BSA in PBS buffer, pH 7.4

Gene Symbols:
DSP, DPI, Desmoplakin, PPKS2, KPPS2, DP, DPII

Immunogen:
Bovine desmoplakin 1 & 2

Quantity:
50 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for up to 12 months.

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Clone:
DP2.15

Gene Accession No.:
NM_001008844.1; NM_004415.2

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Bovine, Chicken, Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma™

CBL180IMI

--


Antigen:
CD62E [ELAM-1]

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.

Gene Symbols:
SELE, ELAM, ELAM1, ESEL, SELP, GMRP, GMP140, GRMP, PSEL

Immunogen:
TNF-activated human umbilical vein endothelial cells.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_000441\NP_002996

Content And Storage:
-20°C for one year from date of shipment; Upon first thaw and prior to removing the cap centrifuge the vial and gently mix the solution; Aliquot into microcentrifuge tubes and store at −20°C; Avoid repeated freeze/thaw cycles

Isotype:
IgG1 κ

Applications:
Functional Assay, ELISA, Flow Cytometry, Immunohistochemistry, Western Blot

Clone:
1.2B6

Gene Accession No.:
P16581\P16109

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified