FEMA549782
Phospho-p53 (Ser9) Recombinant Rabbit Monoclonal Antibody (2E1), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549782-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549782 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
Phospho-p53 (Ser9)
Classification
Recombinant Monoclonal
Concentration
1.2 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P04637
Gene Symbols
Tp53
Immunogen
A synthesized peptide derived from human Phospho-TP53 (S9)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry
Clone
2E1
Conjugate
Unconjugated
Gene
Tp53
Gene Alias
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
7157
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- The tumor suppressor protein, p53, is a sequence specific transcription factor that is activated by cellular stress
- p53 mediates cell cycle arrest or apoptosis in response to DNA damage or starvation for pyrimidine nucleotides
- p53 is up-regulated in response to stress signals and stimulated to activate transcription of specific genes, resulting in expression of p21waf1 and other proteins involved in G1 or G2/M arrest
- The structure of p53 comprises an N-terminal transactivation domain, a central DNA-binding domain, an oligomerisation domain, and a C-terminal regulatory domain
- There are various phosphorylation sites on p53, of which the phosphorylation at Ser15 is important for p53 activation and stabilization
- p53 has been characterized to play a role in blocking the proliferative action of damaged cells and act as an anticancer agent
- Phosphorylation of Ser392 in p53 has been shown to associate with the formation of human tumors
- In addition, p53 has also been linked to the effects of aging and oxidative stress and an increase in p53 has been linked to deficits in LTP (Long Term Potentiation) in learning and memory
- p53 is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy
- Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and cause the loss of tumor suppressor activity
- Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families such as Li-Fraumeni syndrome.
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Antigen: Phospho-p53 (Ser9)
Classification: Recombinant Monoclonal
Concentration: 1.2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P04637
Gene Symbols: Tp53
Immunogen: A synthesized peptide derived from human Phospho-TP53 (S9)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry
Clone: 2E1
Conjugate: Unconjugated
Gene: Tp53
Gene Alias: Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7157
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-p53 (Ser9)
Classification:
Recombinant Monoclonal
Concentration:
1.2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P04637
Gene Symbols:
Tp53
Immunogen:
A synthesized peptide derived from human Phospho-TP53 (S9)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry
Clone:
2E1
Conjugate:
Unconjugated
Gene:
Tp53
Gene Alias:
Antigen NY-CO-13, bbl, BCC7, bfy, bhy, cellular tumor antigen p53, Cys 51 Stop, EGK_08142, FLJ92943, HGNC11998, I79_002739, LFS1, Li-Fraumeni syndrome, mutant p53, mutant tumor protein 53, OTTMUSP00000006194, p44, p53, p53 cellular tumor antigen, p53 protein, p53 tumor suppressor, p53 tumor suppressor phosphoprotein, phosphoprotein p53, Tp53, tp53.L, transformation related protein 53, transformation-related protein 53, Trp248, Trp53, tumor protein 53, tumor protein p53, tumor protein p53 (Li-Fraumeni syndrome), tumor protein p53 L homeolog, tumor suppressor p53, tumor suppressor p53 phosphoprotein, tumor suppressor protein p53, tumor supressor p53, Tumour Protein p53, XELAEV_180196761mg, Xp53, Xrel3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7157
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Phospho-Rb (Ser780)
Classification: Recombinant Monoclonal
Concentration: 0.53 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P06400
Gene Symbols: RB1
Immunogen: A synthesized peptide derived from human Phospho-RB1 (S780)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone: 2E9
Conjugate: Unconjugated
Gene: RB1
Gene Alias: Cleaved Rb, delta RB-p70, DRb-p70, exon 17 tumor GOS561 substitution mutation causes premature stop, GOS563 exon 17 substitution mutation causes premature stop, OSRC, p104, p104 chicken Rb, P105RB, p105-Rb, Phospho-Retinoblastoma, pp105, pp110, PPP1R130, pRb, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, rb, RB transcriptional corepressor 1, RB1, Rb-1, Rb-p70, Retin, Retinoblastoma, retinoblastoma 1, retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 protein, retinoblastoma gene, retinoblastoma isoform A, retinoblastoma protein, retinoblastoma suspectibility protein, retinoblastoma tumor suppressor, retinoblastoma-associated protein
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5925
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-Rb (Ser780)
Classification:
Recombinant Monoclonal
Concentration:
0.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P06400
Gene Symbols:
RB1
Immunogen:
A synthesized peptide derived from human Phospho-RB1 (S780)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation
Clone:
2E9
Conjugate:
Unconjugated
Gene:
RB1
Gene Alias:
Cleaved Rb, delta RB-p70, DRb-p70, exon 17 tumor GOS561 substitution mutation causes premature stop, GOS563 exon 17 substitution mutation causes premature stop, OSRC, p104, p104 chicken Rb, P105RB, p105-Rb, Phospho-Retinoblastoma, pp105, pp110, PPP1R130, pRb, prepro-retinoblastoma-associated protein, protein phosphatase 1, regulatory subunit 130, rb, RB transcriptional corepressor 1, RB1, Rb-1, Rb-p70, Retin, Retinoblastoma, retinoblastoma 1, retinoblastoma 1 (including osteosarcoma), retinoblastoma 1 protein, retinoblastoma gene, retinoblastoma isoform A, retinoblastoma protein, retinoblastoma suspectibility protein, retinoblastoma tumor suppressor, retinoblastoma-associated protein
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5925
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: Phospho-FAK (Tyr397)
Classification: Recombinant Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q05397
Gene Symbols: PTK2
Immunogen: A synthesized peptide derived from human Phospho-PTK2 (Y397)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Clone: 1B3
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5747
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-FAK (Tyr397)
Classification:
Recombinant Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q05397
Gene Symbols:
PTK2
Immunogen:
A synthesized peptide derived from human Phospho-PTK2 (Y397)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
1B3
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
CG10023, CG10023-PA, CG10023-PB, CG10023-PC, CG10023-PD, CG10023-PF, CG10023-PG, CT28129, DFAK, DFak56, Dmel\CG10023, Dmel_CG10023, DmFAK, EC 2.7.10.2, Fadk, FADK 1, Fak, Fak1, Fak56, fak56D, FAK65D, Fak-PA, Fak-PB, Fak-PC, Fak-PD, Fak-PF, Fak-PG, FAK-related non-kinase polypeptide, focal adhesion kinase, Focal adhesion kinase 1, focal adhesion kinase homolog, focal adhesion kinase isoform FAK-Del33, focal adhesion kinase pp125FAK, focal adhesion kinase-related nonkinase, focal ashension kinase 1, FRNK, I79_019430, Kiaa4203, mKIAA4203, p125FAK, p41/p43FRNK, pFAK, pp125 PTK2, pp125FAK, PPP1R71, Protein phosphatase 1 regulatory subunit 71, protein phosphatase 1, regulatory subunit 71, protein tyrosine kinase 2, protein tyrosine kinase 2 L homeolog, protein-tyrosine kinase, protein-tyrosine kinase 2, PTK2, PTK2 protein tyrosine kinase 2, ptk2.L, tyrosine kinase, XELAEV_18032408mg, XPFAK
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5747
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: MIP-3 beta
Classification: Recombinant Monoclonal
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q99731
Gene Symbols: Ccl19
Immunogen: A synthesized peptide derived from human CCL19
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 3A12
Conjugate: Unconjugated
Gene: Ccl19
Gene Alias: beta chemokine exodus-3, beta-chemokine exodus-3, CC chemokine ligand 19, C-C motif chemokine, C-C motif chemokine 19, C-C motif chemokine ligand 19, Ccl19, chemokine (C-C motif) ligand 19, chemokine CCL19, CK beta-11, CKb11, EBI1 ligand chemokine, EBI-1 ligand chemokine, EBI1-ligand chemokine, EBV-induced molecule 1 ligand chemokine, ELC, Epstein-Barr virus-induced molecule 1 ligand chemokine, exodus-3, macrophage inflammatory protein 3 beta, macrophage inflammatory protein 3-beta, MIP3B, MIP-3b, MIP-3-beta, M-MIP-3-beta, SCYA19, small inducible cytokine A19, small inducible cytokine subfamily A (Cys-Cys), member 19, small-inducible cytokine A19
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 6363
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
MIP-3 beta
Classification:
Recombinant Monoclonal
Concentration:
2 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q99731
Gene Symbols:
Ccl19
Immunogen:
A synthesized peptide derived from human CCL19
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
3A12
Conjugate:
Unconjugated
Gene:
Ccl19
Gene Alias:
beta chemokine exodus-3, beta-chemokine exodus-3, CC chemokine ligand 19, C-C motif chemokine, C-C motif chemokine 19, C-C motif chemokine ligand 19, Ccl19, chemokine (C-C motif) ligand 19, chemokine CCL19, CK beta-11, CKb11, EBI1 ligand chemokine, EBI-1 ligand chemokine, EBI1-ligand chemokine, EBV-induced molecule 1 ligand chemokine, ELC, Epstein-Barr virus-induced molecule 1 ligand chemokine, exodus-3, macrophage inflammatory protein 3 beta, macrophage inflammatory protein 3-beta, MIP3B, MIP-3b, MIP-3-beta, M-MIP-3-beta, SCYA19, small inducible cytokine A19, small inducible cytokine subfamily A (Cys-Cys), member 19, small-inducible cytokine A19
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
6363
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG