FEMA550104

Phospho-Tau (Ser199) Recombinant Rabbit Monoclonal Antibody (23E8), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FEMA550104-Each-of-1 In Stock ₹ 35,764.08

FEMA550104 - Each of 1

₹ 35,764.08

In Stock

Quantity

1

Base Price: ₹ 35,764.08

GST (18%): ₹ 6,437.534

Total Price: ₹ 42,201.614

Antigen

Phospho-Tau (Ser199)

Classification

Recombinant Monoclonal

Concentration

0.2 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.

P10636

Gene Symbols

MAPT

Immunogen

A synthesized peptide derived from Human MAPT

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone

23E8

Conjugate

Unconjugated

Gene

MAPT

Gene Alias

AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4137

Content And Storage

-20°C or -80°C if preferred

Isotype

IgG

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Description

  • Tau is a neuronal microtubule-associated protein found predominantly on axons
  • The function of Tau is to promote tubulin polymerization and stabilize microtubules
  • The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
  • Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
  • The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
  • In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
  • Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
  • Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
  • Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

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Show Difference

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Thermo Scientific

FEMA550104

--


Antigen:
Phospho-Tau (Ser199)

Classification:
Recombinant Monoclonal

Concentration:
0.2 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
A synthesized peptide derived from Human MAPT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)

Clone:
23E8

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

Thermo Scientific

FEMA550105

--


Antigen:
Phospho-Tau (Ser404)

Classification:
Recombinant Monoclonal

Concentration:
0.4 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10636

Gene Symbols:
MAPT

Immunogen:
A synthesized peptide derived from Human MAPT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
11H10

Conjugate:
Unconjugated

Gene:
MAPT

Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4137

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

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FEMA550109

--


Antigen:
tPA

Classification:
Recombinant Monoclonal

Concentration:
3 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P00750

Gene Symbols:
PLAT

Immunogen:
A synthesized peptide derived from Human PLAT

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
32B1

Conjugate:
Unconjugated

Gene:
PLAT

Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5327

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG

Img

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FEMA550111

--


Antigen:
IL-8 (CXCL8)

Classification:
Recombinant Monoclonal

Concentration:
1.5 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4

Gene Accession No.:
P10145

Gene Symbols:
CXCL8

Immunogen:
A synthesized peptide derived from Human IL8

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry

Clone:
33A9

Conjugate:
Unconjugated

Gene:
CXCL8

Gene Alias:
(Ala-IL-8)77, (Ser-IL-8)72, Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, ANX7, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine 8, C-X-C motif chemokine ligand 8, CXCL8, cytokine 8, emoctakin, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, GCP1, GCP-1, Granulocyte chemotactic protein 1, IL8, IL-8, IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, ILN, Interleukin, interleukin 8, Interleukin8, interleukin-8, interleuklin-8 precursor, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, Lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF, MDNCF-a, MDNCF-b, MDNCF-c, MONAP, Monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil activating peptide 1, neutrophil and T-lymphocyte chemotactic and activating factor, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Neutrophil-activating factor, neutrophil-activating peptide 1, Neutrophil-activating protein 1, Permeability factor 1, PF1, Protein 3-10C, RP11-537A6.8, RPF1, small inducible cytokine subfamily B, member 8, SNX, SYNEXIN, T-cell chemotactic factor, tumor necrosis factor-induced gene 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3576

Content And Storage:
-20°C or -80°C if preferred

Isotype:
IgG