FEMA550105
Phospho-Tau (Ser404) Recombinant Rabbit Monoclonal Antibody (11H10), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA550105-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA550105 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
Phospho-Tau (Ser404)
Classification
Recombinant Monoclonal
Concentration
0.4 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
P10636
Gene Symbols
MAPT
Immunogen
A synthesized peptide derived from Human MAPT
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
11H10
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4137
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
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Antigen: Phospho-Tau (Ser404)
Classification: Recombinant Monoclonal
Concentration: 0.4 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10636
Gene Symbols: MAPT
Immunogen: A synthesized peptide derived from Human MAPT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 11H10
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4137
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
Phospho-Tau (Ser404)
Classification:
Recombinant Monoclonal
Concentration:
0.4 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10636
Gene Symbols:
MAPT
Immunogen:
A synthesized peptide derived from Human MAPT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
11H10
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4137
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: tPA
Classification: Recombinant Monoclonal
Concentration: 3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P00750
Gene Symbols: PLAT
Immunogen: A synthesized peptide derived from Human PLAT
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry
Clone: 32B1
Conjugate: Unconjugated
Gene: PLAT
Gene Alias: 3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5327
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
tPA
Classification:
Recombinant Monoclonal
Concentration:
3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P00750
Gene Symbols:
PLAT
Immunogen:
A synthesized peptide derived from Human PLAT
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry
Clone:
32B1
Conjugate:
Unconjugated
Gene:
PLAT
Gene Alias:
3.4.21.68, Alteplase, AU020998, AW212668, D8Ertd2e, PATISS, plasminogen activator, tissue, plasminogen activator, tissue type, plasminogen/activator kringle, PLAT, Reteplase, serine protease, t plasminogen activator, tissue plasminogen activator, tissue-type plasminogen activator, Tissue-type plasminogen activator chain A, Tissue-type plasminogen activator chain B, TPA, t-PA, t-plasminogen activator
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5327
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: IL-8 (CXCL8)
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10145
Gene Symbols: CXCL8
Immunogen: A synthesized peptide derived from Human IL8
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry
Clone: 33A9
Conjugate: Unconjugated
Gene: CXCL8
Gene Alias: (Ala-IL-8)77, (Ser-IL-8)72, Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, ANX7, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine 8, C-X-C motif chemokine ligand 8, CXCL8, cytokine 8, emoctakin, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, GCP1, GCP-1, Granulocyte chemotactic protein 1, IL8, IL-8, IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, ILN, Interleukin, interleukin 8, Interleukin8, interleukin-8, interleuklin-8 precursor, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, Lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF, MDNCF-a, MDNCF-b, MDNCF-c, MONAP, Monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil activating peptide 1, neutrophil and T-lymphocyte chemotactic and activating factor, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Neutrophil-activating factor, neutrophil-activating peptide 1, Neutrophil-activating protein 1, Permeability factor 1, PF1, Protein 3-10C, RP11-537A6.8, RPF1, small inducible cytokine subfamily B, member 8, SNX, SYNEXIN, T-cell chemotactic factor, tumor necrosis factor-induced gene 1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3576
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
IL-8 (CXCL8)
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10145
Gene Symbols:
CXCL8
Immunogen:
A synthesized peptide derived from Human IL8
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry
Clone:
33A9
Conjugate:
Unconjugated
Gene:
CXCL8
Gene Alias:
(Ala-IL-8)77, (Ser-IL-8)72, Alveolar macrophage chemotactic factor I, alveolar macrophage-derived chemotactic factor-I, AMCF-I, ANX7, beta endothelial cell-derived neutrophil activating peptide, beta-thromboglobulin-like protein, chemokine (C-X-C motif) ligand 8, C-X-C motif chemokine 8, C-X-C motif chemokine ligand 8, CXCL8, cytokine 8, emoctakin, GCP/IL-8 protein I, GCP/IL-8 protein II, GCP/IL-8 protein III, GCP/IL-8 protein IV, GCP/IL-8 protein V, GCP/IL-8 protein VI, GCP1, GCP-1, Granulocyte chemotactic protein 1, IL8, IL-8, IL-8(1-77), IL-8(5-77), IL-8(6-77), IL-8(7-77), IL-8(8-77), IL-8(9-77), IL8/NAP1 form I, IL8/NAP1 form II, IL8/NAP1 form III, IL8/NAP1 form IV, IL8/NAP1 form V, IL8/NAP1 form VI, ILN, Interleukin, interleukin 8, Interleukin8, interleukin-8, interleuklin-8 precursor, LECT, LUCT, lung giant cell carcinoma-derived chemotactic protein, lymphocyte derived neutrophil activating peptide, Lymphocyte-derived neutrophil-activating factor, LYNAP, MDNCF, MDNCF-a, MDNCF-b, MDNCF-c, MONAP, Monocyte-derived neutrophil chemotactic factor, monocyte-derived neutrophil-activating peptide, NAF, NAP1, NAP-1, neutrophil activating peptide 1, neutrophil and T-lymphocyte chemotactic and activating factor, Neutrophil attractant/activation protein 1, neutrophil attractant/activation protein-1, Neutrophil-activating factor, neutrophil-activating peptide 1, Neutrophil-activating protein 1, Permeability factor 1, PF1, Protein 3-10C, RP11-537A6.8, RPF1, small inducible cytokine subfamily B, member 8, SNX, SYNEXIN, T-cell chemotactic factor, tumor necrosis factor-induced gene 1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3576
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: GAA
Classification: Recombinant Monoclonal
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P10253
Gene Symbols: Gaa
Immunogen: A synthesized peptide derived from Human GAA
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 5E5
Conjugate: Unconjugated
Gene: Gaa
Gene Alias: 70 kDa lysosomal alpha-glucosidase, 76 kDa lysosomal alpha-glucosidase, acid (Pompe disease, glycogen storage disease type II), acid alpha-glucosidase, acid maltase, Aglucosidase alfa, E430018M07Rik, Gaa, glucosidase alpha, acid, glucosidase, alpha, acid, glucosidase, alpha, acid (Pompe disease, glycogen storage disease type II), LYAG, Lysosomal alpha-glucosidase
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2548
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
GAA
Classification:
Recombinant Monoclonal
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P10253
Gene Symbols:
Gaa
Immunogen:
A synthesized peptide derived from Human GAA
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
5E5
Conjugate:
Unconjugated
Gene:
Gaa
Gene Alias:
70 kDa lysosomal alpha-glucosidase, 76 kDa lysosomal alpha-glucosidase, acid (Pompe disease, glycogen storage disease type II), acid alpha-glucosidase, acid maltase, Aglucosidase alfa, E430018M07Rik, Gaa, glucosidase alpha, acid, glucosidase, alpha, acid, glucosidase, alpha, acid (Pompe disease, glycogen storage disease type II), LYAG, Lysosomal alpha-glucosidase
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2548
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG