FEMA549974
Tau Recombinant Human Monoclonal Antibody (8C2), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549974-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549974 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
Tau
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.
P10636, P10637
Gene Symbols
MAPT
Immunogen
Recombinant Human MAPT protein
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Non-human Primate
Form
Liquid
Applications
ELISA, Neutralization
Clone
8C2
Conjugate
Unconjugated
Gene
MAPT
Gene Alias
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species
Human
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
17762, 4137
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG4
Related Products
Description
- Tau is a neuronal microtubule-associated protein found predominantly on axons
- The function of Tau is to promote tubulin polymerization and stabilize microtubules
- The C-terminus binds axonal microtubules while the N- terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both
- Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome
- The short isoforms allow plasticity of the cytoskeleton while the longer isoforms may preferentially play a role in its stabilization
- In its hyper-phosphorylated form, Tau is the major component of paired helical filaments (PHF), the building block of neurofibrillary lesions in Alzheimer's diseases (AD) brain
- Hyper-phosphorylation impairs the microtubule binding function of Tau, resulting in the destabilization of microtubules in AD brains, μgtimately leading to the degeneration of the affected neurons
- Numerous serine/threonine kinases phosphorylate Tau, including GSK-3beta, protein kinase A (PKA), cyclin-dependent kinase 5 (cdk5) and casein kinase II
- Hyper-phosphorylated Tau is found in neurofibrillary lesions in a range and other central nervous system disorders such as Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
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Antigen: Tau
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: P10636, P10637
Gene Symbols: MAPT
Immunogen: Recombinant Human MAPT protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate
Form: Liquid
Applications: ELISA, Neutralization
Clone: 8C2
Conjugate: Unconjugated
Gene: MAPT
Gene Alias: AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17762, 4137
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG4
Antigen:
Tau
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
P10636, P10637
Gene Symbols:
MAPT
Immunogen:
Recombinant Human MAPT protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate
Form:
Liquid
Applications:
ELISA, Neutralization
Clone:
8C2
Conjugate:
Unconjugated
Gene:
MAPT
Gene Alias:
AI413597, AW045860, DDPAC, FLJ31424, FTDP17, FTDP-17, G protein beta1/gamma2 subunit-interacting factor 1, map tau, Mapt, MAPTL, MGC138549, microtubule associated protein tau, microtubule-associated protein tau, microtubule-associated protein tau, isoform 4, microtubules, MSTD, Mtapt, MTBT1, MTBT2, Neurofibrillary tangle protein, neurofibrillary tangles, Neuronal Marker, paired helical filament-tau, PHFtau, PHF-tau, PPND, PPP1R103, protein phosphatase 1, regulatory subunit 103, pTau, RNPTAU, Tau, Tau microtubule-associated protein, tau protein, Tau-4, Tau5, Unknown (protein for MGC:134287)
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17762, 4137
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG4
Antigen: Nectin 4
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: Q96NY8
Gene Symbols: NECTIN4
Immunogen: Recombinant Human NECTIN4 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA
Clone: 6D3
Conjugate: Unconjugated
Gene: NECTIN4
Gene Alias: 1200017F15Rik, EDSS1, ig superfamily receptor LNIR, LNIR, nectin 4, nectin cell adhesion molecule 4, NECTIN4, Nectin-4, poliovirus receptor-related 4, poliovirus receptor-related protein 4, Processed poliovirus receptor-related protein 4, PRR4, Pvrl4, RGD1559826
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 81607
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
Nectin 4
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
Q96NY8
Gene Symbols:
NECTIN4
Immunogen:
Recombinant Human NECTIN4 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA
Clone:
6D3
Conjugate:
Unconjugated
Gene:
NECTIN4
Gene Alias:
1200017F15Rik, EDSS1, ig superfamily receptor LNIR, LNIR, nectin 4, nectin cell adhesion molecule 4, NECTIN4, Nectin-4, poliovirus receptor-related 4, poliovirus receptor-related protein 4, Processed poliovirus receptor-related protein 4, PRR4, Pvrl4, RGD1559826
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
81607
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1
Antigen: ROR1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: Q01973
Gene Symbols: ROR1
Immunogen: Recombinant Human ROR1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Neutralization
Clone: 7H12
Conjugate: Unconjugated
Gene: ROR1
Gene Alias: 2810404D04Rik, dJ537F10.1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, MGC99659, mRor1, neurotrophic tyrosine kinase, receptor related 1, neurotrophic tyrosine kinase, receptor-related 1, Ntrkr1, receptor tyrosine kinase like orphan receptor 1, receptor tyrosine kinase-like orphan receptor 1, RGD1559469, ROR1, T-ROR1, tyrosine-protein kinase transmembrane receptor ROR1
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4919
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
ROR1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
Q01973
Gene Symbols:
ROR1
Immunogen:
Recombinant Human ROR1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Neutralization
Clone:
7H12
Conjugate:
Unconjugated
Gene:
ROR1
Gene Alias:
2810404D04Rik, dJ537F10.1, Inactive tyrosine-protein kinase transmembrane receptor ROR1, MGC99659, mRor1, neurotrophic tyrosine kinase, receptor related 1, neurotrophic tyrosine kinase, receptor-related 1, Ntrkr1, receptor tyrosine kinase like orphan receptor 1, receptor tyrosine kinase-like orphan receptor 1, RGD1559469, ROR1, T-ROR1, tyrosine-protein kinase transmembrane receptor ROR1
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4919
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1
Antigen: C5AR1
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.: P21730
Gene Symbols: C5AR1
Immunogen: Recombinant Human C5AR1 protein
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Neutralization
Clone: 3A7
Conjugate: Unconjugated
Gene: C5AR1
Gene Alias: anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 728
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG1
Antigen:
C5AR1
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.03% Proclin 300, pH 7.4
Gene Accession No.:
P21730
Gene Symbols:
C5AR1
Immunogen:
Recombinant Human C5AR1 protein
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Neutralization
Clone:
3A7
Conjugate:
Unconjugated
Gene:
C5AR1
Gene Alias:
anaphylatoxin C5a receptor, C5A, C5a anaphylatoxin chemotactic receptor, C5a anaphylatoxin chemotactic receptor 1, C5a anaphylatoxin receptor, C5a ligand, C5a Receptor, C5AR, C5a-R, C5AR1, C5r1, Cd88, CD88 antigen, complement C5a receptor, complement C5a receptor 1, complement component 5 receptor 1, complement component 5, receptor 1, complement component 5a receptor 1, D7Msu1
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
728
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG1