FEMA549811
ATM Recombinant Rabbit Monoclonal Antibody (3G11), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FEMA549811-Each-of-1 | In Stock | ₹ 35,764.08 |
FEMA549811 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,764.08
GST (18%): ₹ 6,437.534
Total Price: ₹ 42,201.614
Antigen
ATM
Classification
Recombinant Monoclonal
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
A synthesized peptide derived from human ATM
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone
3G11
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
-20°C or -80°C if preferred
Isotype
IgG
Related Products
Description
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: A synthesized peptide derived from human ATM
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone: 3G11
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
ATM
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
A synthesized peptide derived from human ATM
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin)
Clone:
3G11
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: ISL1
Classification: Recombinant Monoclonal
Concentration: 0.53 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P61371
Gene Symbols: ISL1
Immunogen: A synthesized peptide derived from human Islet 1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Clone: 4F6
Conjugate: Unconjugated
Gene: ISL1
Gene Alias: Insulin gene enhancer protein ISL-1, insulin related protein, ISL LIM homeobox 1, Isl1, Isl-1, isl-1 homeobox, ISL1 transcription factor LIM/homeodomain (islet-1), ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain 1, isl-1=homeobox, Islet 1, ISLET1, islet-1, Lim-homeodomain protein Islet1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3670
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
ISL1
Classification:
Recombinant Monoclonal
Concentration:
0.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P61371
Gene Symbols:
ISL1
Immunogen:
A synthesized peptide derived from human Islet 1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
4F6
Conjugate:
Unconjugated
Gene:
ISL1
Gene Alias:
Insulin gene enhancer protein ISL-1, insulin related protein, ISL LIM homeobox 1, Isl1, Isl-1, isl-1 homeobox, ISL1 transcription factor LIM/homeodomain (islet-1), ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain 1, isl-1=homeobox, Islet 1, ISLET1, islet-1, Lim-homeodomain protein Islet1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3670
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: CD51
Classification: Recombinant Monoclonal
Concentration: 0.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: P06756
Gene Symbols: ITGAV
Immunogen: A synthesized peptide derived from human Integrin alpha V
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: 4G7
Conjugate: Unconjugated
Gene: ITGAV
Gene Alias: 1110004F14Rik, 2610028E01Rik, alpha v integrin, antigen identified by monoclonal antibody L230, Cd51, CD61, D430040G12Rik, Dnmt3l-ps1 pseudogene, GP3A, GPIIIa, integrin alpha V, integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain, integrin alphaVbeta3, integrin subunit alpha V, integrin, alpha V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITGAV, ITGB3, MSK8, Vitronectin receptor, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, VNR, VNRA, VTNR
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3685
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
CD51
Classification:
Recombinant Monoclonal
Concentration:
0.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
P06756
Gene Symbols:
ITGAV
Immunogen:
A synthesized peptide derived from human Integrin alpha V
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
4G7
Conjugate:
Unconjugated
Gene:
ITGAV
Gene Alias:
1110004F14Rik, 2610028E01Rik, alpha v integrin, antigen identified by monoclonal antibody L230, Cd51, CD61, D430040G12Rik, Dnmt3l-ps1 pseudogene, GP3A, GPIIIa, integrin alpha V, integrin alpha-V, Integrin alpha-V heavy chain, Integrin alpha-V light chain, integrin alphaVbeta3, integrin subunit alpha V, integrin, alpha V, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITGAV, ITGB3, MSK8, Vitronectin receptor, vitronectin receptor alpha polypeptide (VNRA), vitronectin receptor subunit alpha, VNR, VNRA, VTNR
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3685
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG
Antigen: IKK beta
Classification: Recombinant Monoclonal
Concentration: 1.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.: O14920
Gene Symbols: Ikbkb
Immunogen: A synthesized peptide derived from human IKK beta
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Western Blot
Clone: 5D12
Conjugate: Unconjugated
Gene: Ikbkb
Gene Alias: AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3551
Content And Storage: -20°C or -80°C if preferred
Isotype: IgG
Antigen:
IKK beta
Classification:
Recombinant Monoclonal
Concentration:
1.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.4
Gene Accession No.:
O14920
Gene Symbols:
Ikbkb
Immunogen:
A synthesized peptide derived from human IKK beta
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Western Blot
Clone:
5D12
Conjugate:
Unconjugated
Gene:
Ikbkb
Gene Alias:
AI132552, AIM-1, FLJ40509, I-kappa-B kinase 2, I-kappa-B-kinase beta, Ikbkb, IKK[b], IKK2, IKK-2, IKKB, IKK-B, IKKbeta, IKK-beta, IMD15, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta, inhibitor of kappaB kinase beta, inhibitor of nuclear factor kappa B kinase beta subunit, inhibitor of nuclear factor kappa-B kinase subunit beta, MGC131801, NFKBIKB, nuclear factor NF-kappa-B inhibitor kinase beta
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3551
Content And Storage:
-20°C or -80°C if preferred
Isotype:
IgG