IM101450UG
MilliporeSigma™ anti-Matriptase/MT-SP1, Polyclonal
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | IM101450UG-Each-of-1 | In Stock | ₹ 25,021.17 |
IM101450UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 25,021.17
GST (18%): ₹ 4,503.811
Total Price: ₹ 29,524.981
Antigen
Matriptase/MT-SP1
Classification
Polyclonal
Formulation
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Immunogen
a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Regulatory Status
RUO
Test Specificity
Recognizes the ∽75kDa matriptase protein in MCF-7 cells.
Content And Storage
2°C to 8°C
Isotype
IgG
Applications
Immunoprecipitation
Conjugate
Unconjugated
Host Species
Rabbit
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects Matriptase/MT-SP1 Clone: in Human samples, and it is validated for Immunoprecipitation Matriptase (MT-SP1, ACC
- No
- NP_068813), a type II membrane serine protease, may play important roles in cell migration and tumor cell metastasis
- It is a mosaic protein with broad spectrum cleavage activity and two potential regulatory modules
- Matriptase can convert hepatocyte growth factor/scatter factor to its active form, which can then activate c-Met tyrosine phosphorylation
- Furthermore, protease-activated receptor 2 (PAR2) and enzymatically inactive single-chain uPA (pro-uPA) were identified as substrates of matriptase
- Matriptase may regulate PAR2 mediated functions such as inflammatory responses, cell adhesion, and uPA-dependent tumor cell invasion and metastasis
- The expression of matriptase is associated with a more invasive phenotype.
Compare Similar Items
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Antigen: Matriptase/MT-SP1
Classification: Polyclonal
Formulation: In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Immunogen: a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Regulatory Status: RUO
Test Specificity: Recognizes the ∽75kDa matriptase protein in MCF-7 cells.
Content And Storage: 2°C to 8°C
Isotype: IgG
Applications: Immunoprecipitation
Conjugate: Unconjugated
Host Species: Rabbit
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Matriptase/MT-SP1
Classification:
Polyclonal
Formulation:
In Tris-citrate/phosphate buffer, pH 7.0-8.0.
Immunogen:
a synthetic peptide corresponding to amino acids near the C-terminus of human matriptase
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽75kDa matriptase protein in MCF-7 cells.
Content And Storage:
2°C to 8°C
Isotype:
IgG
Applications:
Immunoprecipitation
Conjugate:
Unconjugated
Host Species:
Rabbit
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: PAI-1
Classification: Monoclonal
Formulation: Lyophilized from a volatile buffer, 100μg BSA.
Immunogen: partially purified PAI-1 from conditioned medium of dexamethasone-treated HT1080 human cells
Regulatory Status: RUO
Test Specificity: Recognizes both active and latent forms of the ∽50kDa PAI-1 protein in conditioned media from dexamethasone-treated HT-1080 cells. Sold under license of U.S. Patent 5,422,245.
Content And Storage: 2°C to 8°C
Isotype: IgG1
Applications: Immunocytochemistry, Immunoprecipitation, Neutralization
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
PAI-1
Classification:
Monoclonal
Formulation:
Lyophilized from a volatile buffer, 100μg BSA.
Immunogen:
partially purified PAI-1 from conditioned medium of dexamethasone-treated HT1080 human cells
Regulatory Status:
RUO
Test Specificity:
Recognizes both active and latent forms of the ∽50kDa PAI-1 protein in conditioned media from dexamethasone-treated HT-1080 cells. Sold under license of U.S. Patent 5,422,245.
Content And Storage:
2°C to 8°C
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunoprecipitation, Neutralization
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: MMP-2
Classification: Monoclonal
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen: a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status: RUO
Test Specificity: Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage: −20°C
Isotype: IgG1
Applications: Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Human, Mouse, Rat
Form: Purified
Antigen:
MMP-2
Classification:
Monoclonal
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0
Immunogen:
a synthetic peptide (VTPRDKPMGPLLVATF) corresponding to amino acids 468-483 of human MMP-2
Regulatory Status:
RUO
Test Specificity:
Recognizes the ∽72kDa latent and the ∽66kDa active forms of the MMP-2.
Content And Storage:
−20°C
Isotype:
IgG1
Applications:
Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Mouse, Rat
Form:
Purified
Antigen: MMP-1
Classification: Monoclonal
Formulation: In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0, ≤0.1% Sodium Azide.
Immunogen: a synthetic peptide (VQGQNVLHGYPKDIYSSFG) corresponding to amino acids 332-350 of human MMP-1
Regulatory Status: RUO
Test Specificity: __
Content And Storage: -20°C
Isotype: IgG
Applications: Immunohistochemistry (Paraffin)
Conjugate: Unconjugated
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
MMP-1
Classification:
Monoclonal
Formulation:
In 100mM sodium phosphate buffer, 0.1% BSA, pH 7.0, ≤0.1% Sodium Azide.
Immunogen:
a synthetic peptide (VQGQNVLHGYPKDIYSSFG) corresponding to amino acids 332-350 of human MMP-1
Regulatory Status:
RUO
Test Specificity:
__
Content And Storage:
-20°C
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin)
Conjugate:
Unconjugated
Host Species:
Mouse
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid