MA127107

Estrogen Receptor alpha Monoclonal Antibody (6F11), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA127107-Each-of-1 In Stock ₹ 51,592.68

MA127107 - Each of 1

₹ 51,592.68

In Stock

Quantity

1

Base Price: ₹ 51,592.68

GST (18%): ₹ 9,286.682

Total Price: ₹ 60,879.362

Antigen

Estrogen Receptor alpha

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

tissue culture supernatant with 0.09% sodium azide

Gene Accession No.

P03372, P06211, P19785

Gene Symbols

ESR1

Immunogen

Recombinant estrogen receptor protein (alpha form)

Regulatory Status

RUO

Gene ID (Entrez)

13982, 2099, 24890

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

6F11

Conjugate

Unconjugated

Gene

ESR1

Gene Alias

DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species

Mouse

Quantity

250 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG1

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Description

  • Paraffin sections require an antigen retrieval pretreatment with sodium citrate buffer (pH 6.0) prior to staining
  • Use Samboni’s fixative for optimal staining results
  • Positive control of Breast carcinoma suggested
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
  • Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
  • They also play a role in other tissues such as bone
  • Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Compare Similar Items

Show Difference

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Thermo Scientific

MA127107

--


Antigen:
Estrogen Receptor alpha

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P03372, P06211, P19785

Gene Symbols:
ESR1

Immunogen:
Recombinant estrogen receptor protein (alpha form)

Regulatory Status:
RUO

Gene ID (Entrez):
13982, 2099, 24890

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
6F11

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species:
Mouse

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

MA1310

--


Antigen:
Estrogen Receptor alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
Dulbecco's PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P03372, P06211, P19785, P49884

Gene Symbols:
ESR1

Immunogen:
Synthetic peptide corresponding to the residues E(247) V G M M K G G I R K D R R G(261) of the ER alpha DNA binding domain.

Regulatory Status:
RUO

Gene ID (Entrez):
13982, 2099, 24890, 407238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
33

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

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Thermo Scientific

MA133298

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Antigen:
Mouse IgG1

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Proprietary immunogen - Contact ABR for details.

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Control, Flow Cytometry

Clone:
__

Conjugate:
Biotin

Gene:
__

Gene Alias:
IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Host Species:
Mouse

Quantity:
100 Tests

Primary or Secondary:
Secondary

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG1

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MA133380

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Antigen:
TLR4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O00206, P58727, Q68Y56, Q9QUK6

Gene Symbols:
TLR4

Immunogen:
Ba/F3 cell line expressing TLR4

Regulatory Status:
RUO

Gene ID (Entrez):
100724803, 21898, 399541, 403417, 493698, 574360, 7099

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Neutralization

Clone:
HTA125

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2a