PA1309

Estrogen Receptor alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PA1309-Each-of-1 In Stock ₹ 49,881.48

PA1309 - Each of 1

₹ 49,881.48

In Stock

Quantity

1

Base Price: ₹ 49,881.48

GST (18%): ₹ 8,978.666

Total Price: ₹ 58,860.146

Antigen

Estrogen Receptor alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ESR1

Gene Alias

DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

2099, 24890, 397435

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.

P03372, P06211, Q29040

Gene Symbols

ESR1

Immunogen

Synthetic peptide corresponding to residues N(21) E L E P L N R P Q L K(32) C of human ER alpha.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human, Porcine, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • PA1-309 detects estrogen receptor (ER) alpha from human, porcine and rat tissues and cells
  • PA1-309 has been successfully used in Western blot, immunofluoresence and immunohistochemistry procedures
  • By Western blot, this antibody detects an ∽64 kDa protein representing ER alpha from MCF-7 cell extracts
  • Immunohistochemical staining of ER alpha in rat prostate with PA1-309 results in primarily nuclear staining
  • The PA1-309 immunogen is a synthetic peptide corresponding to residues N(21) E L E P L N R P Q L K(32) C of human ER alpha
  • This peptide sequence is completely conserved between human, rat, mouse, rabbit, sheep, porcine and bovine species
  • PA1-309 immunizing peptide (Cat
  • # PEP-037) is available for use in neutralization and control experiments
  • Recombinant ER alpha expressed in baculovirus system (Cat
  • # RP-310) can be purchased for control experiments in Western blot and gel shift assays
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
  • Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
  • They also play a role in other tissues such as bone
  • Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

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PA1309

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Antigen:
Estrogen Receptor alpha

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2099, 24890, 397435

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P03372, P06211, Q29040

Gene Symbols:
ESR1

Immunogen:
Synthetic peptide corresponding to residues N(21) E L E P L N R P Q L K(32) C of human ER alpha.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

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PA130927

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Antigen:
CGRP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Calca

Gene Alias:
alpha-type CGRP; CA; Cal1; CAL6; CALC; Calc1; Calca; calcitonin; calcitonin 1; Calcitonin carboxyl-terminal peptide; Calcitonin gene-related peptide 1; calcitonin gene-related peptide I; calcitonin related polypeptide alpha; calcitonin/calcitonin-related polypeptide, alpha; calcitonin; calcitonin gene-related peptide 1; calcitonin-related polypeptide alpha; CCALCI; CCP; Cgrp; CGRP1; CGRP-1; CGRP-I; Ct; Ctn; Katacalcin; KC; MGC126648; PCT; PDN-21; prepro-alpha-calcitonin gene-related peptide; RAT calcitonin; RATCAL6

Host Species:
Chicken

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
24241, 796

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
whole serum with 0.05% sodium azide

Gene Accession No.:
P01256, P01257, P01258, P06881

Gene Symbols:
Calca

Immunogen:
Rat CGRP (KDNFVPTNVGSEAF-NH2)

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgY

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PA131072

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Antigen:
SOD2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SOD2

Gene Alias:
I79_015272; indophenoloxidase B; IPO B; IPOB; IPO-B; manganese SOD; manganese superoxide dismutase; manganese-containing superoxide dismutase; mangano-superoxide dismutase; manganous superoxide dismutase; mitochondrial superoxide dismutase 2; Mn superoxide dismutase; MNSOD; Mn-SOD; MVCD6; similar to manganous superoxide dismutase; Sod2; Sod-2; sod2.L; sodMt; Superoxide dimutase 2, mitochondrial; superoxide dismutase; superoxide dismutase (Mn type); superoxide dismutase [Mn], mitochondrial; superoxide dismutase 2; superoxide dismutase 2 L homeolog; superoxide dismutase 2, mitochondrial; superoxide dismutase 2, mitochondrial L homeolog

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100154319, 100760320, 103349944, 104973000, 20656, 24787, 281496, 399216, 476258, 6648, 780457

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
0.05M sodium phosphate with 0.1% BSA, 50% glycerol and 0.1% sodium azide; pH 7.2

Gene Accession No.:
P04179, P07895, P09671, P28768, P41976, P41982, P54712

Gene Symbols:
SOD2, sod2.L

Immunogen:
Full length protein (Human).

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Hamster, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat, X. laevis

Product Type:
Antibody

Isotype:
IgG

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PA131075

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Antigen:
CD40

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD40

Gene Alias:
AI326936; B cell surface antigen CD40; B cell-associated molecule; B-cell surface antigen CD40; Bp50; CD antigen CD40; Cd40; CD40 antigen; CD40 antigen (TNF receptor superfamily member 5); CD40 antigen, TNF receptor superfamily member 5; CD40 molecule; CD40 molecule, TNF receptor superfamily member 5; CD40L receptor; CDw40; GP39; HIGM1; I79_006806; IGM; IMD3; Immunoglobulin M; ImmunoglobulinM; membrane protein CD40; MGC9013; p50; receptor for ligand CD154; sCD40; soluble CD40; T-BAM; T-cell differentiation antigen; Tnfrsf5; TRAP; tumor necrosis factor receptor superfamily member 5; tumor necrosis factor receptor superfamily, member 5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100349106, 100728791, 100770242, 171369, 21939, 397395, 403469, 443232, 958

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P25942, P27512, Q7YRL5, Q8SQ34

Gene Symbols:
CD40

Immunogen:
synthetic peptide CQPVTQEDGKESRISVQERQ conjugated to KLH, corresponding to amino acids 258-277 of Human CD40.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Canine, Guinea Pig, Hamster, Human, Mouse, Non-human Primate, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG