MA1310

Estrogen Receptor alpha Monoclonal Antibody (33), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1310-Each-of-1 In Stock ₹ 46,715.76

MA1310 - Each of 1

₹ 46,715.76

In Stock

Quantity

1

Base Price: ₹ 46,715.76

GST (18%): ₹ 8,408.837

Total Price: ₹ 55,124.597

Antigen

Estrogen Receptor alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

Dulbecco's PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.

P03372, P06211, P19785, P49884

Gene Symbols

ESR1

Immunogen

Synthetic peptide corresponding to the residues E(247) V G M M K G G I R K D R R G(261) of the ER alpha DNA binding domain.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry, Western Blot

Clone

33

Conjugate

Unconjugated

Gene

ESR1

Gene Alias

DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

13982, 2099, 24890, 407238

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-310 detects both the steroid occupied and unoccupied forms of the estrogen receptor (ER) alpha from human samples
  • MA1-310 detects ER alpha and does not cross react with ER beta
  • MA1-310 has been successfully used in Western blot, immunohistochemistry, immunoprecipitation, gel shift, flow cytometry, and immunocytochemical experiments
  • By Western blot, this antibody detects an ∽66 kDa protein representing ER alpha from MCF-7 cell extract
  • MA1-310 can be used with blocking peptide PEP-013
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
  • Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
  • They also play a role in other tissues such as bone
  • Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

Compare Similar Items

Show Difference

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Thermo Scientific

MA1310

--


Antigen:
Estrogen Receptor alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
Dulbecco's PBS with 1mg/mL BSA, 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P03372, P06211, P19785, P49884

Gene Symbols:
ESR1

Immunogen:
Synthetic peptide corresponding to the residues E(247) V G M M K G G I R K D R R G(261) of the ER alpha DNA binding domain.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot

Clone:
33

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 group A member 1; RNESTROR; RP1-130E4.1; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
13982, 2099, 24890, 407238

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA133298

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Antigen:
Mouse IgG1

Classification:
Monoclonal

Concentration:
0.1 mg/mL

Formulation:
PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
Proprietary immunogen - Contact ABR for details.

Quantity:
100 Tests

Primary or Secondary:
Secondary

Target Species:
Not Applicable

Product Type:
__

Isotype:
IgG1

Applications:
Control, Flow Cytometry

Clone:
__

Conjugate:
Biotin

Gene:
__

Gene Alias:
IgG1; Igh-4; Ighg1; Immunoglobulin G; Immunoglobulin G1; immunoglobulin heavy constant gamma 1 (G1m marker); ImmunoglobulinG; ImmunoglobulinG1; VH7183

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA133380

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Antigen:
TLR4

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O00206, P58727, Q68Y56, Q9QUK6

Gene Symbols:
TLR4

Immunogen:
Ba/F3 cell line expressing TLR4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Canine, Feline, Guinea Pig, Human, Mouse, Non-human Primate, Porcine, Rhesus Monkey

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Neutralization

Clone:
HTA125

Conjugate:
Unconjugated

Gene:
TLR4

Gene Alias:
ARMD10; CD284; EGK_07381; homolog of Drosophila toll; hToll; lipopolysaccharide response; Lps; Ly87; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; toll like receptor 4; toll/interleukin-l receptor (TIR) domain; toll4; toll-like receptor 4; toll-like receptor 4 immunity-related protein; Toll-like receptor 4-like protein; Toll-like receptor4 protein

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100724803, 21898, 399541, 403417, 493698, 574360, 7099

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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MA133436

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Antigen:
beta-2 Microglobulin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.01% thimerosal

Gene Accession No.:
P61769

Gene Symbols:
B2m

Immunogen:
Purified human beta-2 Microglobulin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2a

Applications:
ELISA, Western Blot

Clone:
B2M-01

Conjugate:
HRP

Gene:
B2m

Gene Alias:
B2m; B2-microglobulin; b2m-W01; b2m-W03; b2m-Z01; b2m-Z02; b2m-Z03; Beta 2 microglobin; Beta 2 microglobulin; beta 2-microglobulin; beta chain of MHC class I molecules; Beta2 microglobulin; beta-2 microglobulin; beta-2 microglobulin preprotein; beta2m; beta2-m; beta-2-microglobin; beta-2-microglobulin; beta-2-microglobulin C-terminal fragment (55 AA); Beta-2-microglobulin form pI 5.3; B-F; CDABP0092; HDCMA22P; IMD43; Lactollin; Ly-m11; MHC Class I; microglobulin beta-2; Orla-B2m

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
567

Content And Storage:
4° C, do not freeze

Form:
Liquid