MAB375CMI
MilliporeSigma™ anti-Tau Clone: Tau-2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MAB375CMI-Each-of-1 | In Stock | ₹ 45,381.02 |
MAB375CMI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
Tau
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P29172
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Tau from bovine, feline and abnormal human tau in Alzheimer's disease.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Immunohistochemistry
Clone
Tau-2
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
MAPT, TAU
Immunogen
Bovine Tau.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_776531
Target Species
Human, Rat
Form
Purified
Related Products
Description
- Specifically detects Tau Clone: Tau-2 in Human, Rat samples, and it is validated for Immunohistochemistry Microtubule-associated protein tau (UniProt P29172; also known as Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau) is encoded by the MAPT (also known as TAU) gene (Gene ID 281296) in bovine species
- Extracellular plaque deposits composed of amyloid-β and intracellular neurofibrillary tangles (NFTs) composed of truncated and hyperphosphorylated tau are two neuropathological hallmarks of Alzheimer's disease (AD)
- Tau pathology (tauopathy) can cause toxicity when the brain is devoid of amyloid plaques, and tangle pathology correlates better with clinical dementia than amyloid pathology
- Abnormal processing of tau by hyperphosphorylation and proteolytic truncation contribute to the toxicity of tau
- Tau is known to be cleaved by various proteases, including caspases, calpains, cathepsins, thrombin, and puromycin-sensitive aminopeptidase, as well as the lysosomal cysteine proteinase asparagine endopeptidase (AEP)
- MAPK, GSK-3, and Cdk-5 are three known kinases that target various tau phosphorylation sites
- Tau also undergoes other types of posttranslational modifications, including glycosylation, ubiquitination, glycation, polyamination, nitration, and lysine methylation, which are believed to be important for its non-pathological functions, including polymerization and stabilization of microtubules.
Compare Similar Items
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Antigen: Tau
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P29172
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Tau from bovine, feline and abnormal human tau in Alzheimer's disease.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry
Clone: Tau-2
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MAPT, TAU
Immunogen: Bovine Tau.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_776531
Target Species: Human, Rat
Form: Purified
Antigen:
Tau
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P29172
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Tau from bovine, feline and abnormal human tau in Alzheimer's disease.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry
Clone:
Tau-2
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MAPT, TAU
Immunogen:
Bovine Tau.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_776531
Target Species:
Human, Rat
Form:
Purified
Antigen: TRAIL/TNFSF10
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P50591
Host Species: Mouse
Purification Method: Protein A or G purified from ascites
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Detects human TRAIL/TNFSF10 in direct ELISAs.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG1
Applications: Immunohistochemistry, Neutralization
Clone: 75411
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: TNFSF10
Immunogen: Mouse myeloma cell line NS0-derived recombinant human TRAIL/TNFSF10 Thr95-Gly281 Accession # P50591
Quantity: 25 μg
Research Discipline: __
Gene ID (Entrez): 8743
Target Species: Human
Form: Purified
Antigen:
TRAIL/TNFSF10
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P50591
Host Species:
Mouse
Purification Method:
Protein A or G purified from ascites
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Detects human TRAIL/TNFSF10 in direct ELISAs.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG1
Applications:
Immunohistochemistry, Neutralization
Clone:
75411
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
TNFSF10
Immunogen:
Mouse myeloma cell line NS0-derived recombinant human TRAIL/TNFSF10 Thr95-Gly281 Accession # P50591
Quantity:
25 μg
Research Discipline:
__
Gene ID (Entrez):
8743
Target Species:
Human
Form:
Purified
Antigen: CCL27/CTACK
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_006655
Host Species: Mouse
Purification Method: Protein A or G purified from hybridoma culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Detects human CCL27/CTACK in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CCL27, recombinant human (rh) CCL25, or rhCCL19 is observed.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG2a
Applications: Immunohistochemistry, ELISA
Clone: 124302
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: CCL27
Immunogen: E. coli-derived recombinant human CCL27/CTACK Phe25-Gly112 Accession # NP_006655
Quantity: 500 μg
Research Discipline: __
Gene ID (Entrez): 10850
Target Species: Human
Form: Purified
Antigen:
CCL27/CTACK
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_006655
Host Species:
Mouse
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Detects human CCL27/CTACK in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse CCL27, recombinant human (rh) CCL25, or rhCCL19 is observed.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG2a
Applications:
Immunohistochemistry, ELISA
Clone:
124302
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
CCL27
Immunogen:
E. coli-derived recombinant human CCL27/CTACK Phe25-Gly112 Accession # NP_006655
Quantity:
500 μg
Research Discipline:
__
Gene ID (Entrez):
10850
Target Species:
Human
Form:
Purified
Antigen: CCL27/CTACK
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_006655
Host Species: Mouse
Purification Method: Protein A or G purified from hybridoma culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Detects human CCL27/CTACK in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, recombinant mouse CCL1, 2, 3, 4, 5, 6, 7, 9/10, 11, 12, 17, 19, 20, 21, 22, 24, 25, or recombinant rat CCL20 is observed.
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG1
Applications: Western Blot, Immunohistochemistry, Neutralization
Clone: 124308
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: CCL27
Immunogen: E. coli-derived recombinant human CCL27/CTACK Phe25-Gly112 Accession # NP_006655
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): 10850
Target Species: Human
Form: Supernatant
Antigen:
CCL27/CTACK
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_006655
Host Species:
Mouse
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Detects human CCL27/CTACK in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 11, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, recombinant mouse CCL1, 2, 3, 4, 5, 6, 7, 9/10, 11, 12, 17, 19, 20, 21, 22, 24, 25, or recombinant rat CCL20 is observed.
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG1
Applications:
Western Blot, Immunohistochemistry, Neutralization
Clone:
124308
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
CCL27
Immunogen:
E. coli-derived recombinant human CCL27/CTACK Phe25-Gly112 Accession # NP_006655
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
10850
Target Species:
Human
Form:
Supernatant