MABF2119100

CD318 (CD6L), Mouse anti-Human, Clone: 3A11, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF2119100-Each-of-1 In Stock ₹ 43,200.96

MABF2119100 - Each of 1

₹ 43,200.96

In Stock

Quantity

1

Base Price: ₹ 43,200.96

GST (18%): ₹ 7,776.173

Total Price: ₹ 50,977.133

Antigen

CD318 (CD6L)

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

CDCP1;TRASK

Immunogen

HBL-100 human mammary gland epithelial cells.

Quantity

100 μg

Research Discipline

Inflammation & Immunology

Gene ID (Entrez)

NP_073753.3

Target Species

Human

Form

Purified

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

3A11

Dilution

Immunoprecipitation Analysis: A representative lot immunoprecipitated CD318 (CD6L) in Immunoprecipitation applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Immunohistochemistry (Paraffin) Analysis: A representative lot detected CD318 (CD6L) in Immunohistochemistry applications (Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Western Blotting Analysis: A representative lot detected CD318 (CD6L) in Western Blotting applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Flow Cytometry Analysis: A representative lot detected CD318 (CD6L) in Flow Cytometry applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).

Gene Alias

CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD6L

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 3A11 specifically detects CD318 in human cells. It targets an epitope with in the extracellular domain.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Anti-CD318 (CD6L), clone 3A11, Cat
  • No
  • MABF2119, is a mouse monoclonal antibody that detects CD318 (CD6L) and has been tested for use in Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, and Western Blotting
  • CUB domain-containing protein 1 (UniProt: Q9H5V8; also known as Membrane glycoprotein gp140, Subtractive immunization M plus HEp3-associated 135 kDa protein, SIMA135, Transmembrane and associated with Src kinases, CD318, CD6L) is encoded by the CDCP1 (also known as TRASK) gene (Gene ID:64866) in human
  • CD318 is a single-pass membrane protein (isoform 1) that serves as a ligand for CD6
  • It is highly expressed in mitotic cells and has low expression during interphase
  • It is detected in high levels in skeletal muscle and colon tissue and in lower levels in kidney, placenta, lungs, and small intestine
  • Its levels are shown to be up-regulated in several human cancer tissues
  • It is also expressed in high levels in synovial tissues where it participates in CD6-dependent adhesion of T cells to synovial fibroblasts
  • CD318 is shown to be chemoattractive to T cells and levels of soluble CD318 are increased in the synovial fluid from patients with rheumatoid arthritis and juvenile inflammatory arthritis
  • CD318 is synthesized with a signal peptide (aa 1-29), which is cleaved off in the mature form
  • It has an extracellular domain (aa 30-667), a transmembrane domain (aa 668-688), and a cytoplasmic domain (aa 689-836)
  • Three isoforms of CD318 have been described that are produced by alternative splicing
  • (Ref.: Enyindah-Asonye, G., et al
  • (2017)
  • Proc
  • Natl
  • Acad
  • Sci
  • USA 114(33); E6912-E6921).

Compare Similar Items

Show Difference

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Fischer Scientific

MABF2119100

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Antigen:
CD318 (CD6L)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
CDCP1;TRASK

Immunogen:
HBL-100 human mammary gland epithelial cells.

Quantity:
100 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_073753.3

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
3A11

Dilution:
Immunoprecipitation Analysis: A representative lot immunoprecipitated CD318 (CD6L) in Immunoprecipitation applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Immunohistochemistry (Paraffin) Analysis: A representative lot detected CD318 (CD6L) in Immunohistochemistry applications (Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Western Blotting Analysis: A representative lot detected CD318 (CD6L) in Western Blotting applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Flow Cytometry Analysis: A representative lot detected CD318 (CD6L) in Flow Cytometry applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).

Gene Alias:
CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD6L

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3A11 specifically detects CD318 in human cells. It targets an epitope with in the extracellular domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Fischer Scientific

MABF211925

--


Antigen:
CD318 (CD6L)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
CDCP1;TRASK

Immunogen:
HBL-100 human mammary gland epithelial cells.

Quantity:
25 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_073753.3

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
3A11

Dilution:
Immunoprecipitation Analysis: A representative lot immunoprecipitated CD318 (CD6L) in Immunoprecipitation applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Immunohistochemistry (Paraffin) Analysis: A representative lot detected CD318 (CD6L) in Immunohistochemistry applications (Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Western Blotting Analysis: A representative lot detected CD318 (CD6L) in Western Blotting applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).Flow Cytometry Analysis: A representative lot detected CD318 (CD6L) in Flow Cytometry applications (Saifullah, M.K., et. al. (2004). J Immunol. 173(10):6125-33; Enyindah-Asonye, G., et. al. (2017). Proc Natl Acad Sci U S A. 114(33):E6912-E6921).

Gene Alias:
CUB domain-containing protein 1;Membrane glycoprotein gp140;Subtractive immunization M plus HEp3-associated 135 kDa protein;SIMA135;Transmembrane and associated with src kinases;CD6L

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3A11 specifically detects CD318 in human cells. It targets an epitope with in the extracellular domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

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MABF2122100

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Antigen:
PCBP2 (hnRNP E2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
PCBP2

Immunogen:
His-tagged full-length human recombinant Poly(rC)-binding protein 2.

Quantity:
100 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_001122383

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
PC 81-1

Dilution:
Western Blotting Analysis: A representative lot detected PCBP2 (hnRNP E2) in Western Blotting applications (Sean, P., et. al. (2008). Virology. 378(2):243-53; Chase, A.J., et. al. (2014). Virology. 449:35-44).Immunocytochemistry Analysis: A representative lot detected PCBP2 (hnRNP E2) in Immunocytochemistry applications (Fitzgerald, K.D., et. at. (2011). PLoS Pathog. 7(7):e1002127).Western Blotting Analysis: 1μg/mL from a representative lot detected PCBP2 (hnRNP E2) in SK-N-SH cell lysate.

Gene Alias:
Poly(rC)-binding protein 2;Alpha-CP2;Heterogeneous nuclear ribonucleoprotein E2;hnRNP E2

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone PC 81-1 specifically detects Poly(rC)-binding protein 2 in human cells.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ

Img

Fischer Scientific

MABF212225

--


Antigen:
PCBP2 (hnRNP E2)

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
PCBP2

Immunogen:
His-tagged full-length human recombinant Poly(rC)-binding protein 2.

Quantity:
25 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_001122383

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
PC 81-1

Dilution:
Western Blotting Analysis: A representative lot detected PCBP2 (hnRNP E2) in Western Blotting applications (Sean, P., et. al. (2008). Virology. 378(2):243-53; Chase, A.J., et. al. (2014). Virology. 449:35-44).Immunocytochemistry Analysis: A representative lot detected PCBP2 (hnRNP E2) in Immunocytochemistry applications (Fitzgerald, K.D., et. at. (2011). PLoS Pathog. 7(7):e1002127).Western Blotting Analysis: 1μg/mL from a representative lot detected PCBP2 (hnRNP E2) in SK-N-SH cell lysate.

Gene Alias:
Poly(rC)-binding protein 2;Alpha-CP2;Heterogeneous nuclear ribonucleoprotein E2;hnRNP E2

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone PC 81-1 specifically detects Poly(rC)-binding protein 2 in human cells.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ