MABN2485100

Cdc42, Mouse anti-Mouse, Yeast, Human, Clone: 28-10, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN2485100-Each-of-1 In Stock ₹ 41,308.37

MABN2485100 - Each of 1

₹ 41,308.37

In Stock

Quantity

1

Base Price: ₹ 41,308.37

GST (18%): ₹ 7,435.507

Total Price: ₹ 48,743.877

Antigen

Cdc42

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

CDC42;SRO2;TLR229C;L8083.13

Immunogen

GST-tagged full-length recombinant yeast Cdc42.

Quantity

100 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_013330

Target Species

Mouse, Yeast, Human

Form

Purified

Applications

Immunocytochemistry, Western Blot

Clone

28-10

Dilution

Western Blotting Analysis: A representative lot detected Cdc42 in Western Blotting applications (Sullivan, C.S., et. al. (2016). J Biol Chem. 291(51):26262-26272; Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).Immunocytochemistry Analysis: A representative lot detected Cdc42 in Immunocytochemistry applications (Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).

Gene Alias

Cell division control protein 42;Suppressor of RHO3 protein 2

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 28-10 specifically detects Cell division control protein 42 (Cdc42).

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Anti-Cdc42, clone 28-10, Cat
  • No
  • MABN2485, is a highly specific mouse monoclonal antibody that targets Cell division control protein 42 (Cdc42) and has been tested for use in Immunocytochemistry and Western Blotting
  • Cell division control protein 42 (UniProt: P19073; also known as Cdc42, Suppressor of RHO3 protein 2) is encoded by the CDC42 (also known as SRO2, TLR229C, L8083.13) gene (Gene ID: 850930) in yeast (Saccharomyces cerevisiae)
  • Cdc42 is a member of the Rho GTPase family that regulates multiple signaling pathways involved in actomyosin organization, cell proliferation, and maintenance of cell polarity in most eukaryotic cell types
  • Cdc42 signaling process involves guanine nucleotide exchange factors (GEFs), guanine nucleotide dissociation inhibitors (GDIs), and GTPase-activating proteins (GAPs)
  • In yeast, generation and maintenance of robust Cdc42 polarity promotes membrane expansion during bud formation and it has been shown that Cdc42 is dynamically maintained at the polarity cap through its continuous cycling between the polarity cap and internal pools
  • Cdc42 is highly polarized during bud emergence and is specifically required for exocytosis at this stage
  • Cdc42 is synthesized with a propeptide region (aa 189-191), which is cleaved off in the mature form
  • The mature form contains three nucleotide (GTP)-binding sites
  • (Ref.: Wu, H., and Brennwald, P
  • (2010) Mol
  • Cell Biol
  • 30(21); 5207-5217).

Compare Similar Items

Show Difference

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Fischer Scientific

MABN2485100

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Antigen:
Cdc42

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
CDC42;SRO2;TLR229C;L8083.13

Immunogen:
GST-tagged full-length recombinant yeast Cdc42.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_013330

Target Species:
Mouse, Yeast, Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
28-10

Dilution:
Western Blotting Analysis: A representative lot detected Cdc42 in Western Blotting applications (Sullivan, C.S., et. al. (2016). J Biol Chem. 291(51):26262-26272; Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).Immunocytochemistry Analysis: A representative lot detected Cdc42 in Immunocytochemistry applications (Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).

Gene Alias:
Cell division control protein 42;Suppressor of RHO3 protein 2

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 28-10 specifically detects Cell division control protein 42 (Cdc42).

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Img

Fischer Scientific

MABN248525

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Antigen:
Cdc42

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
CDC42;SRO2;TLR229C;L8083.13

Immunogen:
GST-tagged full-length recombinant yeast Cdc42.

Quantity:
25 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_013330

Target Species:
Mouse, Human, Yeast

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
28-10

Dilution:
Western Blotting Analysis: A representative lot detected Cdc42 in Western Blotting applications (Sullivan, C.S., et. al. (2016). J Biol Chem. 291(51):26262-26272; Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).Immunocytochemistry Analysis: A representative lot detected Cdc42 in Immunocytochemistry applications (Wu, H., et. al. (2010). Mol Cell Biol. 30(21):5207-17).

Gene Alias:
Cell division control protein 42;Suppressor of RHO3 protein 2

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 28-10 specifically detects Cell division control protein 42 (Cdc42).

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

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MABN24901MI

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Antigen:
mutant HTT

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
HTT, HD, IT15

Immunogen:
GST-tagged recombinant exon1 of wild-type human huntingtin HTTx1 (20Q) protein.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Human, Mouse

Form:
Purified

Applications:
Dot Blot, Immunohistochemistry (Paraffin), Western Blot

Clone:
PHP1

Dilution:
__

Gene Alias:
Huntingtin;Huntington disease protein;HD protein

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone PHP1 is mouse monoclonal antibody that detects mutated Huntingtin protein. It targets an epitope QAQPLLPQP within the proline-rich domain.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Isotype:
IgG1 κ

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MABN24902MI

--


Antigen:
mutant HTT

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
__

Gene Symbols:
HTT, HD, IT15

Immunogen:
GST-tagged recombinant exon1 of wild-type human huntingtin HTTx1 (20Q) protein.

Quantity:
25 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
__

Target Species:
Human, Mouse

Form:
Purified

Applications:
Dot Blot, Immunohistochemistry (Paraffin), Western Blot

Clone:
PHP1

Dilution:
__

Gene Alias:
Huntingtin;Huntington disease protein;HD protein

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
Clone PHP1 is mouse monoclonal antibody that detects mutated Huntingtin protein. It targets an epitope QAQPLLPQP within the proline-rich domain.

Content And Storage:
Stable for 1 year at -20°C from date of receipt.

Isotype:
IgG1 κ