MABT843
MilliporeSigma™ SYNE1, Mouse, Unlabeled, Clone: 7A12,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT843-Each-of-1 | In Stock | ₹ 37,728.54 |
MABT843 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,728.54
GST (18%): ₹ 6,791.137
Total Price: ₹ 44,519.677
Antigen
SYNE1
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q8NF91
Immunogen
GST-tagged recombinant human SYNE1 isoform Beta C-terminal 121-a.a. fragment fused to full-length isoform Alpha sequence (UniProt Q8NF91-2 andQ8NF91-3).
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_892006
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
7A12
Conjugate
Unconjugated
Gene
SYNE1, C6orf98, EDMD4, KIAA0796, KIAA1262, KIAA1756, MYNE1, SCAR8
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Epitope region is present in, human isoforms 1 (Giant; Enaptin)/2 (Beta)/3 (Alpha)/4/5/8 (Beta 2)/9 (Alpha 2)/11 (myne-1; 131kDa), mouse isoforms 1 (Giant; Enaptin)/2/3 (Syne-1A)/4 (Syne-1B)), and rat Nesprin-1 (UniProt Q8VHJ9), but absent from human spliced isoforms 6/7/10 (drop1)/12 (GSRP-56; 56 kDa), mouse spliced isoform 5 (Enaptin-165), or rat spliced isoform CPG2 (UniProt Q63128) reported by UniProt (Q8NF91, Q6ZWR6, Q8VHJ9, Q63128). Clone 7A12 does not reacts with nesprin-2, but stained centrosome in acetone/methanol-fixed HeLa cells due to uncharacterized cross-reactivity (Randles, K.N., et al. (2010). Dev. Dyn. 239(3):998-1009).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Description Nesprin-1 (UniProt Q8NF91; also known as Enaptin, Myne-1, Myocyte nuclear envelope protein 1, Nuclear envelope spectrin repeat protein 1, Synaptic nuclear envelope protein 1, Syne-1) is encoded by the SYNE1 (also known as C6orf98, EDMD4, KIAA0796, KIAA1262, KIAA1756, MYNE1, SCAR8) gene (Gene ID 23345) in human
- SYNE1 gene encodes multiple intracellular linker/scaffold molecules as a result of alternate start codons usage and splicings
- Structurally, nesprins have a central rod domain composed of spectrin repeats
- Nesprin-1 isoforms giant/4/5/6/7/10 and nesprin-2 isoforms giant/p32CH/NUANCE-N-33 have two N-terminal CH (calponin homology) domains that bind the actin cytoskeleton
- Nesprin-1 isoforms giant/beta/alpha/4/beta 2/alpha 2/myne-1 and Nesprin-2 isoforms giant/2/epsilon2/beta1/alpha1/alpha2/gamma/beta2/FLJ56122/FLJ55476/epsilon1 contain a C-terminal transmembrane KASH (Klarsicht-ANC-Syne-homology) domain that resides in the outer nuclear membrane and bind across the luminal space to the SUN (Sad1, UNC84) type II inner nuclear membrane proteins, SUN1 and SUN2, to form LINC (Linker of Nucleoskeleton and Cytoskeleton) complexes that link the cytoskeleton and the nucleus
- Human SYNE1 gene is among the top ten loci conferring risk for the five major psychiatric disorders, schizophrenia, bipolar disorder (BD), major depression, attention deficit-hyperactivity disorder (ADHD), and autism spectrum disorder (ASD), as well as multiple other neurological and neuromuscular disorders.
Compare Similar Items
Show Difference
Antigen: SYNE1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q8NF91
Immunogen: GST-tagged recombinant human SYNE1 isoform Beta C-terminal 121-a.a. fragment fused to full-length isoform Alpha sequence (UniProt Q8NF91-2 andQ8NF91-3).
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_892006
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 7A12
Conjugate: Unconjugated
Gene: SYNE1, C6orf98, EDMD4, KIAA0796, KIAA1262, KIAA1756, MYNE1, SCAR8
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Epitope region is present in, human isoforms 1 (Giant; Enaptin)/2 (Beta)/3 (Alpha)/4/5/8 (Beta 2)/9 (Alpha 2)/11 (myne-1; 131kDa), mouse isoforms 1 (Giant; Enaptin)/2/3 (Syne-1A)/4 (Syne-1B)), and rat Nesprin-1 (UniProt Q8VHJ9), but absent from human spliced isoforms 6/7/10 (drop1)/12 (GSRP-56; 56 kDa), mouse spliced isoform 5 (Enaptin-165), or rat spliced isoform CPG2 (UniProt Q63128) reported by UniProt (Q8NF91, Q6ZWR6, Q8VHJ9, Q63128). Clone 7A12 does not reacts with nesprin-2, but stained centrosome in acetone/methanol-fixed HeLa cells due to uncharacterized cross-reactivity (Randles, K.N., et al. (2010). Dev. Dyn. 239(3):998-1009).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
SYNE1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q8NF91
Immunogen:
GST-tagged recombinant human SYNE1 isoform Beta C-terminal 121-a.a. fragment fused to full-length isoform Alpha sequence (UniProt Q8NF91-2 andQ8NF91-3).
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_892006
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
7A12
Conjugate:
Unconjugated
Gene:
SYNE1, C6orf98, EDMD4, KIAA0796, KIAA1262, KIAA1756, MYNE1, SCAR8
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Epitope region is present in, human isoforms 1 (Giant; Enaptin)/2 (Beta)/3 (Alpha)/4/5/8 (Beta 2)/9 (Alpha 2)/11 (myne-1; 131kDa), mouse isoforms 1 (Giant; Enaptin)/2/3 (Syne-1A)/4 (Syne-1B)), and rat Nesprin-1 (UniProt Q8VHJ9), but absent from human spliced isoforms 6/7/10 (drop1)/12 (GSRP-56; 56 kDa), mouse spliced isoform 5 (Enaptin-165), or rat spliced isoform CPG2 (UniProt Q63128) reported by UniProt (Q8NF91, Q6ZWR6, Q8VHJ9, Q63128). Clone 7A12 does not reacts with nesprin-2, but stained centrosome in acetone/methanol-fixed HeLa cells due to uncharacterized cross-reactivity (Randles, K.N., et al. (2010). Dev. Dyn. 239(3):998-1009).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: MYH-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-1.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_109604
Target Species: Mouse, Rat
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: 6F12H3
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6F12H3 is a rat monoclonal antibody that detects Myosin-1 in mouse and rat muscles. It target an epitope within the coiled coil domain in the C-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
MYH-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-1.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_109604
Target Species:
Mouse, Rat
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
6F12H3
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6F12H3 is a rat monoclonal antibody that detects Myosin-1 in mouse and rat muscles. It target an epitope within the coiled coil domain in the C-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: MYH-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-1.
Quantity: 25 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_109604
Target Species: Mouse, Rat
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Clone: 6F12H3
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6F12H3 is a rat monoclonal antibody that detects Myosin-1 in mouse and rat muscles. It target an epitope within the coiled coil domain in the C-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
MYH-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-1.
Quantity:
25 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_109604
Target Species:
Mouse, Rat
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry, Western Blot
Clone:
6F12H3
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6F12H3 is a rat monoclonal antibody that detects Myosin-1 in mouse and rat muscles. It target an epitope within the coiled coil domain in the C-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: MYH-4
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-4.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_034985
Target Species: Mouse, Rat
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: 2G72F10
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 2G72F10 is a rat monoclonal antibody that detects Myosin-4 in mouse and rat muscles. It targets an epitope within 29 amino acids from the C-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
MYH-4
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 29 amino acids from the C-terminal half of murine Myosin-4.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_034985
Target Species:
Mouse, Rat
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
2G72F10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 2G72F10 is a rat monoclonal antibody that detects Myosin-4 in mouse and rat muscles. It targets an epitope within 29 amino acids from the C-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ