NBP24515702
Cadherin-16 Antibody (CDH16/1071), Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
Cadherin-16
Classification
Monoclonal
Concentration
0.2mg/mL
Dilution
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Accession No.
O75309
Gene Symbols
CDH16
Immunogen
Recombinant human CDH16 protein
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
1014
Target Species
Human, Mouse, Rat, Canine, Rabbit
Form
Purified
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
CDH16/1071
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias
cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
Host Species
Mouse
Molecular Weight of Antigen
130 kDa
Quantity
0.2 mg
Primary or Secondary
Primary
Test Specificity
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- Ensure accurate, reproducible results in Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence Cadherin-16 Monoclonal specifically detects Cadherin-16 in Human, Mouse, Rat, Canine, Rabbit samples
- It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Cadherin-16
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Accession No.: O75309
Gene Symbols: CDH16
Immunogen: Recombinant human CDH16 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 1014
Target Species: Human, Mouse, Rat, Canine, Rabbit
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: CDH16/1071
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
Host Species: Mouse
Molecular Weight of Antigen: 130 kDa
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Cadherin-16
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, Immunofluorescence 1 - 2 ug/ml
Gene Accession No.:
O75309
Gene Symbols:
CDH16
Immunogen:
Recombinant human CDH16 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
1014
Target Species:
Human, Mouse, Rat, Canine, Rabbit
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
CDH16/1071
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
cadherin 16, KSP-cadherin, cadherin-16, Kidney-specific cadherin, KSP-cadherin
Host Species:
Mouse
Molecular Weight of Antigen:
130 kDa
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 130kDa, identified as Ksp-cadherin. Cadherins form a superfamily of related glycoproteins that mediate calcium-dependent cell adhesion and transmit signals from the extracellular matrix to the cytoplasm. Cadherins have been implicated in embryogenesis, tissue morphogenesis, tissue structure maintenance, cell polarization, neoplastic invasiveness and metastasis, and membrane transport. It is suggested that Ksp-cadherin is a marker for terminal differentiation of the basolateral membranes of renal tubular epithelial cells. Within the kidney, Ksp-Cadherin is found exclusively in the basolateral membrane of renal tubular epithelial cells and collecting duct cells, and not in glomeruli, renal interstitial cells, or blood vessels.Ksp-Cadherin has been suggested to distinguish Chromophobe Renal-Cell Carcinoma from Oncocytoma.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: MITF
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: MITF
Immunogen: NH2 terminus fragment of human Mi protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 4286
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone: D5
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.02 mg
Primary or Secondary: Primary
Test Specificity: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
MITF
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
MITF
Immunogen:
NH2 terminus fragment of human Mi protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
4286
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone:
D5
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.02 mg
Primary or Secondary:
Primary
Test Specificity:
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: MITF
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: MITF
Immunogen: NH2 terminus fragment of human Mi protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 4286
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone: D5
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
MITF
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
MITF
Immunogen:
NH2 terminus fragment of human Mi protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
4286
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone:
D5
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: MITF
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.: __
Gene Symbols: MITF
Immunogen: NH2 terminus fragment of human Mi protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 4286
Target Species: Human, Mouse (Negative), Rat (Negative)
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone: D5
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias: BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
MITF
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page, Immunofluorescence 0.5 - 1.0 ug/ml
Gene Accession No.:
__
Gene Symbols:
MITF
Immunogen:
NH2 terminus fragment of human Mi protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
4286
Target Species:
Human, Mouse (Negative), Rat (Negative)
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), SDS-Page, Immunofluorescence
Clone:
D5
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Alias:
BHLHE32, bHLHe32MI, Class E basic helix-loop-helix protein 32, microphthalmia-associated transcription factor, Waardenburg syndrome, type 2A, WS2A
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
MITF (microphthalmia transcription factor) is a basic helix-loop-helix-leucine-zipper (bHLH-Zip) transcription factor that regulates the development and survival of melanocytes and retinal pigment epithelium, and also is involved in transcription of pigmentation enzyme genes such as tyrosinase TRP1 and TRP2. MITF has been shown to be phosphorylated by MAP kinase in response to c-kit activation, resulting in upregulation of MITF transcriptional activity. Mutations of the MITF gene are associated with the autosomal dominant hereditary deafness and pigmentation condition, Waardenburg Syndrome type 2A. Multiple isoforms of MITF exist, including MITF-A, MITF-B, MITF-C, MITF-H, and MITF-M, which differ in the amino-terminal domain and in their expression patterns. The MITF-M isoform is restricted to the melanocyte cell lineage. Anti-MITF, D5, recognizes a nuclear protein, which is expressed in the majority of primary and metastatic epithelioid malignant melanomas as well as in normal melanoc
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ