NBP275729
Mammaglobin A Antibody (MGB/2000) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275729-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275729 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Mammaglobin A
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.
Q13296
Gene Symbols
SCGB2A2
Immunogen
Recombinant full-length human Mammaglobin A protein (Uniprot: Q13296)
Purification Method
Protein A or G purified
Primary or Secondary
Primary
Test Specificity
Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.
Content And Storage
Store at 4°C.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin)
Clone
MGB/2000
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
mammaglobin 1, mammaglobin A, Mammaglobin-1, MGB1mammaglobin-A, MGC71974, Secretoglobin family 2A member 2, secretoglobin, family 2A, member 2, UGB2mammaglobin-1
Host Species
Mouse
Molecular Weight of Antigen
18 kDa
Quantity
100 μg
Gene ID (Entrez)
4250.0
Target Species
Human
Form
Purified
Description
- Mammaglobin A Monoclonal specifically detects Mammaglobin A in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Mammaglobin A
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.: Q13296
Gene Symbols: SCGB2A2
Immunogen: Recombinant full-length human Mammaglobin A protein (Uniprot: Q13296)
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: MGB/2000
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: mammaglobin 1, mammaglobin A, Mammaglobin-1, MGB1mammaglobin-A, MGC71974, Secretoglobin family 2A member 2, secretoglobin, family 2A, member 2, UGB2mammaglobin-1
Host Species: Mouse
Molecular Weight of Antigen: 18 kDa
Quantity: 100 μg
Gene ID (Entrez): 4250.0
Target Species: Human
Form: Purified
Antigen:
Mammaglobin A
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.:
Q13296
Gene Symbols:
SCGB2A2
Immunogen:
Recombinant full-length human Mammaglobin A protein (Uniprot: Q13296)
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Mammaglobin is a 93 amino acid glycoprotein with homology to other secretoglobin-uteroglobin family members. It was originally identified as a breast cancer restricted biomarker by differential screening. Mammaglobin related to secretoglobin family that includes human uteroglobin and lipophilin. Mammaglobin antibody stains cytoplasm of normal breast epithelial cells as well as primary and metastatic breast carcinomas. Mammaglobin expression is absent in prostate, kidney, colon, rectum, small intestine, stomach, pancreas, lung, and thyroid tissues. Mammaglobin may be used as part of an immunohistochemical panel for determination of metastatic breast carcinoma and tumor of unknown primary origin.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
MGB/2000
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
mammaglobin 1, mammaglobin A, Mammaglobin-1, MGB1mammaglobin-A, MGC71974, Secretoglobin family 2A member 2, secretoglobin, family 2A, member 2, UGB2mammaglobin-1
Host Species:
Mouse
Molecular Weight of Antigen:
18 kDa
Quantity:
100 μg
Gene ID (Entrez):
4250.0
Target Species:
Human
Form:
Purified
Antigen: MTAP
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot : 0.5-2 ug/ml, ELISA 2 - 4 ug/mL, Immunohistochemistry 1 - 2 ug/mL, Immunohistochemistry-Paraffin : 1-2 ug/ml, Protein Array
Gene Accession No.: __
Gene Symbols: MTAP
Immunogen: Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary) (Uniprot: Q13126)
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Applications: Western Blot, ELISA, Immunohistochemistry (Paraffin)
Clone: MTAP/1813
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: 5'-methylthioadenosine phosphorylase, c86fus, EC 2.4.2.28, methylthioadenosine phosphorylase, MSAPMeSAdo phosphorylase, MTA phosphorylase, MTAPase, S-methyl-5'-thioadenosine phosphorylase
Host Species: Mouse
Molecular Weight of Antigen: 31 kDa
Quantity: 100 μg
Gene ID (Entrez): 4507.0
Target Species: Human
Form: Purified
Antigen:
MTAP
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot : 0.5-2 ug/ml, ELISA 2 - 4 ug/mL, Immunohistochemistry 1 - 2 ug/mL, Immunohistochemistry-Paraffin : 1-2 ug/ml, Protein Array
Gene Accession No.:
__
Gene Symbols:
MTAP
Immunogen:
Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary) (Uniprot: Q13126)
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 31kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase). It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Applications:
Western Blot, ELISA, Immunohistochemistry (Paraffin)
Clone:
MTAP/1813
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
5'-methylthioadenosine phosphorylase, c86fus, EC 2.4.2.28, methylthioadenosine phosphorylase, MSAPMeSAdo phosphorylase, MTA phosphorylase, MTAPase, S-methyl-5'-thioadenosine phosphorylase
Host Species:
Mouse
Molecular Weight of Antigen:
31 kDa
Quantity:
100 μg
Gene ID (Entrez):
4507.0
Target Species:
Human
Form:
Purified
Antigen: OCT2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P09086
Gene Symbols: POU2F2
Immunogen: Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: OCT2/2136
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Host Species: Mouse
Molecular Weight of Antigen: 60 kDa
Quantity: 100 μg
Gene ID (Entrez): 5452.0
Target Species: Human
Form: Purified
Antigen:
OCT2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P09086
Gene Symbols:
POU2F2
Immunogen:
Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
OCT2/2136
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Host Species:
Mouse
Molecular Weight of Antigen:
60 kDa
Quantity:
100 μg
Gene ID (Entrez):
5452.0
Target Species:
Human
Form:
Purified
Antigen: Perforin
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P14222
Gene Symbols: PRF1
Immunogen: Recombinant human Perforin protein fragment (around aa 413-552) (exact sequence is proprietary) (Uniprot: P14222)
Purification Method: Protein A or G purified
Primary or Secondary: Primary
Test Specificity: Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin)
Clone: PRF1/2468
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: Cytolysin, FLH2, HPLH2, HPLH2lymphocyte pore forming protein, Lymphocyte pore-forming protein, MGC65093, P1PFN1, perforin 1 (pore forming protein), perforin-1, PFPcytolysin
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 100 μg
Gene ID (Entrez): 5551.0
Target Species: Human
Form: Purified
Antigen:
Perforin
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P14222
Gene Symbols:
PRF1
Immunogen:
Recombinant human Perforin protein fragment (around aa 413-552) (exact sequence is proprietary) (Uniprot: P14222)
Purification Method:
Protein A or G purified
Primary or Secondary:
Primary
Test Specificity:
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
PRF1/2468
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
Cytolysin, FLH2, HPLH2, HPLH2lymphocyte pore forming protein, Lymphocyte pore-forming protein, MGC65093, P1PFN1, perforin 1 (pore forming protein), perforin-1, PFPcytolysin
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
100 μg
Gene ID (Entrez):
5551.0
Target Species:
Human
Form:
Purified