PA184165
Amyloid Precursor Protein Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA184165-Each-of-1 | In Stock | ₹ 49,496.46 |
PA184165 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,496.46
GST (18%): ₹ 8,909.363
Total Price: ₹ 58,405.823
Antigen
Amyloid Precursor Protein
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APP
Gene Alias
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11820, 351, 54226
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 0.02% sodium azide; pH 7.4
Gene Accession No.
P05067, P08592, P12023
Gene Symbols
APP
Immunogen
Synthetic peptide corresponding to residues 737-751 of human APP.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-84165 recognizes both intact APP and also the C99 fragment generated by Beta-secretase
- The sequence recognized by this antibody corresponds to amino acids 85-99 of the C99 fragment
- Heat-mediated antigen retrieval is recommended for the staining of paraffin sections
- Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
- Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
- The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
- Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
- Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
- The remnant protein is processed by another protease, gamma-secretase
- Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
- Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
- The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
- Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
- Alzheimer’s disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
- Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.
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Antigen: Amyloid Precursor Protein
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APP
Gene Alias: A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11820, 351, 54226
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide; pH 7.4
Gene Accession No.: P05067, P08592, P12023
Gene Symbols: APP
Immunogen: Synthetic peptide corresponding to residues 737-751 of human APP.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Amyloid Precursor Protein
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APP
Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11820, 351, 54226
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide; pH 7.4
Gene Accession No.:
P05067, P08592, P12023
Gene Symbols:
APP
Immunogen:
Synthetic peptide corresponding to residues 737-751 of human APP.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Laminin A/B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LAMA1
Gene Alias: AA408497; alternatively spliced laminin gamma2 chain; AW211941; B2T; basement membrane adhesion protein; BM600; BM600-100kDa; C77966; C80098; C81607; Cell-scattering factor 140 kDa subunit; CLM; CSF; CSF 140 kDa subunit; D130003D08Rik; EBR2; EBR2A; Epiligrin subunit gamma; extra-cellular matrix protein; gamma 1 (formerly LAMB2); hypothetical protein; kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; LAMA; Lama1; Lama-1; LAMB1; Lamb-1; Lamb1-1; LAMB2; Lamb-2; LAMB2T; LAMC1; LAMC2; laminin 5 gamma 2 subunit; laminin A chain; laminin alpha 1; laminin alpha 1 chain; laminin B1; laminin B1 chain; laminin B1 subunit 1; laminin B1s chain; Laminin B2 chain; laminin B2t chain; laminin beta 2 subunit chain; laminin beta 2-like chain; laminin beta-1-1 chain; Laminin beta-1-2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1; laminin S; laminin subunit alpha 1; laminin subunit alpha-1; laminin subunit beta 1; laminin subunit beta 2; Laminin subunit beta-1; laminin subunit beta-1 variant; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma 2; laminin subunit gamma-1; Laminin subunit gamma-2; laminin, alpha 1; laminin, beta 1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1 (formerly LAMB2); laminin, gamma 2; laminin-1; laminin-1 subunit alpha; Laminin-1 subunit beta; Laminin-1 subunit gamma; Laminin-10 subunit beta; laminin-10 subunit gamma; Laminin-11 subunit beta; laminin-11 subunit gamma; Laminin-12 subunit beta; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit beta; Laminin-2 subunit gamma; laminin-3 subunit alpha; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; laminin-5 gamma 2; Laminin-5 subunit gamma; Laminin-6 subunit beta; laminin-6 subunit gamma; Laminin-7 subunit beta; laminin-7 subunit gamma; Laminin-8 subunit beta; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMNB2; Lams; Large adhesive scatter factor 140 kDa subunit; LIS5; Nicein subunit gamma; NPHS5; npht; PTBHS; SLAM; S-LAM alpha; S-LAM beta; S-LAM gamma; S-LAM-alpha; S-laminin subunit alpha; S-laminin subunit beta; S-laminin subunit gamma
Host Species: Rabbit
Purification Method: __
Regulatory Status: RUO
Gene ID (Entrez): 100009388, 100357482, 100358679, 102156629, 16772, 16777, 16779, 25473, 284217, 298941, 316758, 373980, 374016, 3912, 3913, 396478, 475882, 476626
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration: Conc. Not Determined
Formulation: whole serum with 0.09% sodium azide
Gene Accession No.: P02469, P07942, P15800, P19137, P25391, P55268, Q01635, Q61292
Gene Symbols: LAMA1, LAMB1, LAMB2
Immunogen: Purified laminin from Engelbreth-Holm-Swarm (EHS) tumor.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Avian, Canine, Chicken, Human, Mouse, Rabbit, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Laminin A/B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LAMA1
Gene Alias:
AA408497; alternatively spliced laminin gamma2 chain; AW211941; B2T; basement membrane adhesion protein; BM600; BM600-100kDa; C77966; C80098; C81607; Cell-scattering factor 140 kDa subunit; CLM; CSF; CSF 140 kDa subunit; D130003D08Rik; EBR2; EBR2A; Epiligrin subunit gamma; extra-cellular matrix protein; gamma 1 (formerly LAMB2); hypothetical protein; kalinin subunit gamma; Kalinin/nicein/epiligrin 100 kDa subunit; Ladsin 140 kDa subunit; LAMA; Lama1; Lama-1; LAMB1; Lamb-1; Lamb1-1; LAMB2; Lamb-2; LAMB2T; LAMC1; LAMC2; laminin 5 gamma 2 subunit; laminin A chain; laminin alpha 1; laminin alpha 1 chain; laminin B1; laminin B1 chain; laminin B1 subunit 1; laminin B1s chain; Laminin B2 chain; laminin B2t chain; laminin beta 2 subunit chain; laminin beta 2-like chain; laminin beta-1-1 chain; Laminin beta-1-2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1; laminin S; laminin subunit alpha 1; laminin subunit alpha-1; laminin subunit beta 1; laminin subunit beta 2; Laminin subunit beta-1; laminin subunit beta-1 variant; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma 2; laminin subunit gamma-1; Laminin subunit gamma-2; laminin, alpha 1; laminin, beta 1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1 (formerly LAMB2); laminin, gamma 2; laminin-1; laminin-1 subunit alpha; Laminin-1 subunit beta; Laminin-1 subunit gamma; Laminin-10 subunit beta; laminin-10 subunit gamma; Laminin-11 subunit beta; laminin-11 subunit gamma; Laminin-12 subunit beta; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit beta; Laminin-2 subunit gamma; laminin-3 subunit alpha; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; laminin-5 gamma 2; Laminin-5 subunit gamma; Laminin-6 subunit beta; laminin-6 subunit gamma; Laminin-7 subunit beta; laminin-7 subunit gamma; Laminin-8 subunit beta; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMNB2; Lams; Large adhesive scatter factor 140 kDa subunit; LIS5; Nicein subunit gamma; NPHS5; npht; PTBHS; SLAM; S-LAM alpha; S-LAM beta; S-LAM gamma; S-LAM-alpha; S-laminin subunit alpha; S-laminin subunit beta; S-laminin subunit gamma
Host Species:
Rabbit
Purification Method:
__
Regulatory Status:
RUO
Gene ID (Entrez):
100009388, 100357482, 100358679, 102156629, 16772, 16777, 16779, 25473, 284217, 298941, 316758, 373980, 374016, 3912, 3913, 396478, 475882, 476626
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Concentration:
Conc. Not Determined
Formulation:
whole serum with 0.09% sodium azide
Gene Accession No.:
P02469, P07942, P15800, P19137, P25391, P55268, Q01635, Q61292
Gene Symbols:
LAMA1, LAMB1, LAMB2
Immunogen:
Purified laminin from Engelbreth-Holm-Swarm (EHS) tumor.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Avian, Canine, Chicken, Human, Mouse, Rabbit, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TGF alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TGFA
Gene Alias: EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7039
Content And Storage: -20°C
Form: Lyophilized
Applications: ELISA, Functional Assay, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: P01135
Gene Symbols: TGFA
Immunogen: Recombinant human TGF-alpha
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TGF alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TGFA
Gene Alias:
EGF-like TGF; ETGF; I79_019067; LOC100009150; Protransforming growth factor alpha; RATTGFAA; TFGA; TGF a; TGF type 1; TGF a; TGFA; TGFAA; TGFalpha; TGF-alpha; TGFa; Transforming growth factor; Transforming growth factor alpha; transforming growth factor, alpha; transforming growth factor-alpha; wa1; wa-1; waved 1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7039
Content And Storage:
-20°C
Form:
Lyophilized
Applications:
ELISA, Functional Assay, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
P01135
Gene Symbols:
TGFA
Immunogen:
Recombinant human TGF-alpha
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: NCoR2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCOR2
Gene Alias: CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; nuclear receptor corepressor; nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; SMRT; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20602, 9612
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q9WU42, Q9Y618
Gene Symbols: NCOR2
Immunogen: His-tagged fusion protein corresponding to amino acid residues 95-565 from human SMRT.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NCoR2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCOR2
Gene Alias:
CTG repeat protein 26; CTG26; N-CoR; NCOR2; N-CoR2; nuclear receptor corepressor; nuclear receptor corepressor 2; nuclear receptor co-repressor 2; silencing mediator for retinoid and thyroid hormone receptors; silencing mediator of retinoic acid and thyroid hormone receptor; silencing mediator of retinoid acid and thyroid hormone receptor; SMAP270; SMRT; SMRTe; SMRTE-tau; T3 receptor-associating factor; Thyroid-, retinoic-acid-receptor-associated corepressor; TNRC14; TRAC; TRAC1; TRAC-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20602, 9612
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q9WU42, Q9Y618
Gene Symbols:
NCOR2
Immunogen:
His-tagged fusion protein corresponding to amino acid residues 95-565 from human SMRT.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG