PIMA511757
Bcl-2 Monoclonal Antibody (100/D5), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA511757-Each-of-1 | In Stock | ₹ 51,421.56 |
PIMA511757 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,421.56
GST (18%): ₹ 9,255.881
Total Price: ₹ 60,677.441
Antigen
Bcl-2
Classification
Monoclonal
Concentration
0.2 mg/mL
Formulation
10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4
Gene Accession No.
P10415, P10417
Gene Symbols
Bcl2
Immunogen
A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
Quantity
500 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
100/D5
Conjugate
Unconjugated
Gene
Bcl2
Gene Alias
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species
Mouse
Purification Method
Protein A/G
Regulatory Status
RUO
Gene ID (Entrez)
12043, 596
Content And Storage
4° C
Form
Liquid
Related Products
Description
- MA5-11757 targets BCL-2 in FACS, ICC/IF, IHC (P), IP, and WB applications and shows reactivity with Human and mouse samples
- The MA5-11757 immunogen is a synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
- BCL-2 is a key regulator of apoptosis that functions to either inhibit or promote cell death
- The BCL-2 family members are also characterized by dimerizing to further modulate apoptosis
- Bag1, for example, has been found to form a heterodimer with BCL-2 resulting in the enhancement of the anti-apoptotic effect of BCL-2
- Bax and Bak have been shown to play a critical role in cytochrome c release from mitochondria and thus initiate apoptosis
- Bax exerts a pro-apoptotic rather than an anti-apoptotic effect on cells
- Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma
- In most follicular lymphomas, neoplastic germinal centers express high levels of BCL-2 alpha protein, whereas the normal or hyperplastic germinal centers are negative
- Two transcript variants of BCL-2, produced by alternate splicing, differ in their C-terminal ends
- The overexpression of BCL-2 has been linked to human cancers such as B-cell lymphoma and prostate cancer.
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Antigen: Bcl-2
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: 10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4
Gene Accession No.: P10415, P10417
Gene Symbols: Bcl2
Immunogen: A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 100/D5
Conjugate: Unconjugated
Gene: Bcl2
Gene Alias: apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 12043, 596
Content And Storage: 4° C
Form: Liquid
Antigen:
Bcl-2
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
10mM PBS with 0.05% BSA and 0.05% sodium azide, pH 7.4
Gene Accession No.:
P10415, P10417
Gene Symbols:
Bcl2
Immunogen:
A synthetic peptide, aa 41-54 (GAAPAPGIFSSQPG-Cys) of human Bcl-2 protein
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
100/D5
Conjugate:
Unconjugated
Gene:
Bcl2
Gene Alias:
apoptosis regulator Bcl-2; AW986256; B cell leukemia/lymphoma 2; B cell lymphoma 2 associated oncogene; B-cell CLL/lymphoma 2; B-cell leukemia/lymphoma 2; Bcl 2; BCL2; bcl-2; BCL2 apoptosis regulator; Bcl-2 protein; BCL2, apoptosis regulator; Bcl2-like protein; C430015F12Rik; D630044D05Rik; D830018M01Rik; OTTHUMP00000163680; PPP1R50; protein phosphatase 1, regulatory subunit 50
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
12043, 596
Content And Storage:
4° C
Form:
Liquid
Antigen: TPM1
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P04268, P04692, P09493
Gene Symbols: TPM1
Immunogen: Tropomyosin protein purified from chicken embryo fibroblasts (CEF) and chicken leg, heart, and gizzard
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Chicken, Human, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: CH1
Conjugate: Unconjugated
Gene: TPM1
Gene Alias: AA986836; AI854628; alpha tropomyosin; alpha tropomyosin of brain; alpha tropomyosin of fibroblasts F2; alpha-fTM; Alpha-tm; alpha-Tm-1; alpha-Tm-2 isoform; alpha-tropomyosin; alpha-tropomyosin (partial); alpha-tropomyosin 1; alpha-tropomyosin 2; alpha-tropomyosin of skeletal fast muscle; C15orf13; cardiac alpha tropomyosin; cardiomyopathy, hypertrophic 3; CMD1Y; CMH3; epididymis secretory protein Li 265; HEL-S-265; hepatoma alpha tropomyosin; HTM-alpha; LVNC9; sarcomeric tropomyosin kappa; smooth muscle alpha-tropomyosin; striated muscle alpha-tropomyosin; Tm1; TM2; Tm3; Tma2; Tmpa; Tmsa; Tpm1; Tpm-1; tpm1 protein; TPM1-1; TPM1-alpha; TPMA; tropomyosin; tropomyosin (CTm4); tropomyosin (CTm7); tropomyosin 1; tropomyosin 1 (alpha); tropomyosin 1 alpha chain; tropomyosin 1, alpha; tropomyosin 1-1; tropomyosin 3 alpha; tropomyosin alpha-1 chain; Tropomyosin-1; unnamed protein product; zgc:171719; zgc:55951; zgc:77009
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 24851, 396366, 7168
Content And Storage: 4° C
Form: Liquid
Antigen:
TPM1
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P04268, P04692, P09493
Gene Symbols:
TPM1
Immunogen:
Tropomyosin protein purified from chicken embryo fibroblasts (CEF) and chicken leg, heart, and gizzard
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Chicken, Human, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
CH1
Conjugate:
Unconjugated
Gene:
TPM1
Gene Alias:
AA986836; AI854628; alpha tropomyosin; alpha tropomyosin of brain; alpha tropomyosin of fibroblasts F2; alpha-fTM; Alpha-tm; alpha-Tm-1; alpha-Tm-2 isoform; alpha-tropomyosin; alpha-tropomyosin (partial); alpha-tropomyosin 1; alpha-tropomyosin 2; alpha-tropomyosin of skeletal fast muscle; C15orf13; cardiac alpha tropomyosin; cardiomyopathy, hypertrophic 3; CMD1Y; CMH3; epididymis secretory protein Li 265; HEL-S-265; hepatoma alpha tropomyosin; HTM-alpha; LVNC9; sarcomeric tropomyosin kappa; smooth muscle alpha-tropomyosin; striated muscle alpha-tropomyosin; Tm1; TM2; Tm3; Tma2; Tmpa; Tmsa; Tpm1; Tpm-1; tpm1 protein; TPM1-1; TPM1-alpha; TPMA; tropomyosin; tropomyosin (CTm4); tropomyosin (CTm7); tropomyosin 1; tropomyosin 1 (alpha); tropomyosin 1 alpha chain; tropomyosin 1, alpha; tropomyosin 1-1; tropomyosin 3 alpha; tropomyosin alpha-1 chain; Tropomyosin-1; unnamed protein product; zgc:171719; zgc:55951; zgc:77009
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
24851, 396366, 7168
Content And Storage:
4° C
Form:
Liquid
Antigen: ARF6
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.: P62330, P62331
Gene Symbols: ARF6
Immunogen: ARF6 protein
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 6ARF01
Conjugate: Unconjugated
Gene: ARF6
Gene Alias: ADP ribosylation factor 6; ADP-ribosylation factor 6; AI788669; ARF6; AW496366; DKFZp564M0264
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 11845, 382
Content And Storage: 4° C
Form: Liquid
Antigen:
ARF6
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene Accession No.:
P62330, P62331
Gene Symbols:
ARF6
Immunogen:
ARF6 protein
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
6ARF01
Conjugate:
Unconjugated
Gene:
ARF6
Gene Alias:
ADP ribosylation factor 6; ADP-ribosylation factor 6; AI788669; ARF6; AW496366; DKFZp564M0264
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
11845, 382
Content And Storage:
4° C
Form:
Liquid
Antigen: Involucrin
Classification: Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.: P07476, P18174, P18175, P48998
Gene Symbols: IVL
Immunogen: Human keratinocytes' involucrin
Quantity: 500 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Non-human Primate, Porcine, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: SY5
Conjugate: Unconjugated
Gene: IVL
Gene Alias: 1110019C06Rik; involucrin; IVL
Host Species: Mouse
Purification Method: Protein A/G
Regulatory Status: RUO
Gene ID (Entrez): 101125010, 102152041, 3713, 407242, 60583
Content And Storage: 4° C
Form: Liquid
Antigen:
Involucrin
Classification:
Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 0.05% BSA and 0.05% sodium azide; pH 7.4
Gene Accession No.:
P07476, P18174, P18175, P48998
Gene Symbols:
IVL
Immunogen:
Human keratinocytes' involucrin
Quantity:
500 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Non-human Primate, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
SY5
Conjugate:
Unconjugated
Gene:
IVL
Gene Alias:
1110019C06Rik; involucrin; IVL
Host Species:
Mouse
Purification Method:
Protein A/G
Regulatory Status:
RUO
Gene ID (Entrez):
101125010, 102152041, 3713, 407242, 60583
Content And Storage:
4° C
Form:
Liquid