PIMA516038
BUBR1 Monoclonal Antibody (8G1), HRP, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516038-Each-of-1 | In Stock | ₹ 45,731.82 |
PIMA516038 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,731.82
GST (18%): ₹ 8,231.728
Total Price: ₹ 53,963.548
Antigen
BUBR1
Classification
Monoclonal
Concentration
0.6 mg/mL
Formulation
PBS with no preservative
Gene Accession No.
O60566, Q9Z1S0
Gene Symbols
BUB1B
Immunogen
A portion of hBUBR1 tagged at the N-terminus with pMAL (residues 1-350 of human BUBR1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG1 κ
Applications
Western Blot
Clone
8G1
Conjugate
HRP
Gene
BUB1B
Gene Alias
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
12236, 701
Content And Storage
4° C, store in dark
Form
Liquid
Related Products
Description
- This antibody should not cross-react with hBUB1
- BUBR1 is a member of the Ser/Thr protein kinase family
- It is a component of the mitotic checkpoint that delays anaphase until all chromosome are properly attached to the mitotic spindle
- Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to malignant transformations
- Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
- They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
- hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
- BUBR1 has been detected in human cancers
- It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.
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Antigen: BUBR1
Classification: Monoclonal
Concentration: 0.6 mg/mL
Formulation: PBS with no preservative
Gene Accession No.: O60566, Q9Z1S0
Gene Symbols: BUB1B
Immunogen: A portion of hBUBR1 tagged at the N-terminus with pMAL (residues 1-350 of human BUBR1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Western Blot
Clone: 8G1
Conjugate: HRP
Gene: BUB1B
Gene Alias: AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 12236, 701
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
BUBR1
Classification:
Monoclonal
Concentration:
0.6 mg/mL
Formulation:
PBS with no preservative
Gene Accession No.:
O60566, Q9Z1S0
Gene Symbols:
BUB1B
Immunogen:
A portion of hBUBR1 tagged at the N-terminus with pMAL (residues 1-350 of human BUBR1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
8G1
Conjugate:
HRP
Gene:
BUB1B
Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
12236, 701
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: BUBR1
Classification: Monoclonal
Concentration: 0.6 mg/mL
Formulation: 50mM sodium borate with no preservative
Gene Accession No.: O60566, Q9Z1S0
Gene Symbols: BUB1B
Immunogen: A portion of hBUBR1 tagged at the N-terminus with pMAL (residues 1-350 of human BUBR1).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 8G1
Conjugate: DyLight 550
Gene: BUB1B
Gene Alias: AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 12236, 701
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
BUBR1
Classification:
Monoclonal
Concentration:
0.6 mg/mL
Formulation:
50mM sodium borate with no preservative
Gene Accession No.:
O60566, Q9Z1S0
Gene Symbols:
BUB1B
Immunogen:
A portion of hBUBR1 tagged at the N-terminus with pMAL (residues 1-350 of human BUBR1).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
8G1
Conjugate:
DyLight 550
Gene:
BUB1B
Gene Alias:
AU045529; BUB1 budding uninhibited by benzimidazoles 1 homolog beta; BUB1 mitotic checkpoint serine/threonine kinase B; Bub1A; Bub1b; BUB1B, mitotic checkpoint serine/threonine kinase; BUB1beta; BUBR1; budding uninhibited by benzimidazoles 1 beta; budding uninhibited by benzimidazoles 1 homolog beta; budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae); hBub1; hBUBR1; MAD3/BUB1-related protein kinase; MAD3L; Mitotic checkpoint kinase MAD3L; mitotic checkpoint serine/threonine-protein kinase BUB1 beta; MVA1; Protein SSK1; SSK1
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
12236, 701
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: RPE65
Classification: Monoclonal
Concentration: 0.79 mg/mL
Formulation: 50mM sodium borate with 0.05% sodium azide
Gene Accession No.: O70276, Q16518, Q28175, Q91ZQ5, Q9TVB8, Q9YGX2
Gene Symbols: RPE65
Immunogen: Bovine RPE microsomal membrane proteins.
Quantity: 200 μL
Primary or Secondary: Primary
Target Species: Bovine, Canine, Chicken, Human, Mouse, Non-human Primate, Porcine, Rat, X. laevis
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 401.8B11.3D9
Conjugate: DyLight 650
Gene: RPE65
Gene Alias: 65kDa; A930029L06Rik; all-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; LCA2; Lutein isomerase; membrane receptor p63; meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mord1; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific 65kD protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; retinal pigment epithelium-specific protein RPE65; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); retinoid isomerohydrolase; retinoid isomerohydrolase RPE65; retinol isomerase; RP20; RPE65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; sRPE65; truncated RPE65
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100516743, 19892, 282043, 395700, 403803, 6121, 89826
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
RPE65
Classification:
Monoclonal
Concentration:
0.79 mg/mL
Formulation:
50mM sodium borate with 0.05% sodium azide
Gene Accession No.:
O70276, Q16518, Q28175, Q91ZQ5, Q9TVB8, Q9YGX2
Gene Symbols:
RPE65
Immunogen:
Bovine RPE microsomal membrane proteins.
Quantity:
200 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Canine, Chicken, Human, Mouse, Non-human Primate, Porcine, Rat, X. laevis
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
401.8B11.3D9
Conjugate:
DyLight 650
Gene:
RPE65
Gene Alias:
65kDa; A930029L06Rik; all-trans-retinyl-palmitate hydrolase; BCO family, member 3; BCO3; LCA2; Lutein isomerase; membrane receptor p63; meso-zeaxanthin isomerase; modifier of retinal degeneration 1; Mord1; mRPE65; p63; RBP-binding membrane protein; rd12; retinal pigment epithelium 65; retinal pigment epithelium 65-like; retinal pigment epithelium abundant protein RPE65; retinal pigment epithelium specific protein 65; retinal pigment epithelium, 65 kDa; retinal pigment epithelium-specific 65 kDa protein; retinal pigment epithelium-specific 65kD protein; retinal pigment epithelium-specific protein (65kD); retinal pigment epithelium-specific protein 65kDa; retinal pigment epithelium-specific protein RPE65; Retinitis pigmentos; retinitis pigmentosa 20 (autosomal recessive); retinoid isomerohydrolase; retinoid isomerohydrolase RPE65; retinol isomerase; RP20; RPE65; rpe65 gene for retinal pigment epithelium-specific protein; RPE65, retinoid isomerohydrolase; sRPE65; truncated RPE65
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100516743, 19892, 282043, 395700, 403803, 6121, 89826
Content And Storage:
4° C, store in dark
Form:
Liquid
Antigen: BRCA1
Classification: Monoclonal
Concentration: 1.43 mg/mL
Formulation: 50mM sodium borate with 0.05% sodium azide
Gene Accession No.: P38398
Gene Symbols: BRCA1
Immunogen: Human BRCA1 (between residues 1314-1864).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG2a
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: RAY
Conjugate: DyLight 650
Gene: BRCA1
Gene Alias: brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 672
Content And Storage: 4° C, store in dark
Form: Liquid
Antigen:
BRCA1
Classification:
Monoclonal
Concentration:
1.43 mg/mL
Formulation:
50mM sodium borate with 0.05% sodium azide
Gene Accession No.:
P38398
Gene Symbols:
BRCA1
Immunogen:
Human BRCA1 (between residues 1314-1864).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG2a
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
RAY
Conjugate:
DyLight 650
Gene:
BRCA1
Gene Alias:
brca 1; Brca1; brca-1; BRCA1, DNA repair associated; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; breast and ovarian cancer susceptibility protein 1; breast and ovarian cancer sususceptibility protein 1; breast cancer 1; breast cancer 1 early onset; breast cancer 1, early onset; breast cancer associated 1; breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; BROVCA1; BROVCA12; Delta772-3095; early onset breast cancer 1; Fanconi anemia, complementation group S; FANCS; IRIS; OTTHUMP00000212147; OTTHUMP00000212148; OTTHUMP00000212149; OTTHUMP00000212150; OTTHUMP00000212151; OTTHUMP00000212155; PNCA4; PPP1R53; protein phosphatase 1, regulatory subunit 53; PSCP; RING finger protein 53; RING-type E3 ubiquitin transferase BRCA1; RNF53; truncated BRCA1; truncated breast and ovarian cancer susceptibility protein 1; truncated breast and ovarian cancer sususceptibility protein 1; truncated breast cancer type 1 susceptibility protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
672
Content And Storage:
4° C, store in dark
Form:
Liquid