PIMA516149
OPA1 Monoclonal Antibody (1E8-1D9), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA516149-Each-of-1 | In Stock | ₹ 51,079.32 |
PIMA516149 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 51,079.32
GST (18%): ₹ 9,194.278
Total Price: ₹ 60,273.598
Antigen
OPA1
Classification
Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O60313, P58281, Q2TA68
Gene Symbols
OPA1
Immunogen
Human OPA1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Bovine, Hamster, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
1E8-1D9
Conjugate
Unconjugated
Gene
OPA1
Gene Alias
1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
100751873, 171116, 4976, 524142, 74143
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Related Products
Description
- In Western blot, multiple protein isoforms can be seen at approximately 90, 80 and 65 kDa
- OPA1 is a dynamin-related GTPase that is critical for the maintenance of mitochondrial morphology and mtDNA
- The most commonly associated phenotype with OPA1 mutations is heterozygous optic atrophy, a heterozygous dominant trait that causes reduced visual clarity and sometimes blindness
- The disease usually begins in childhood and increases in severity throughout the life of affected individuals
- Usually, this phenotype is attributed to the degeneration of optic nerve fibers
- Interestingly, the same type of nerve degeneration seems to be partially causative of certain schizophrenia characteristics
- OPA1 dysfunction also seems to be implicated in this case; mitochondrial networks associated with critical nerves seem to link schizophrenia and OPA1
- The dysfunction is associated with issues with apoptosis and normal cellular metabolic regulation, all regulated through OPA1.
Compare Similar Items
Show Difference
Antigen: OPA1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O60313, P58281, Q2TA68
Gene Symbols: OPA1
Immunogen: Human OPA1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Hamster, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 1E8-1D9
Conjugate: Unconjugated
Gene: OPA1
Gene Alias: 1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 100751873, 171116, 4976, 524142, 74143
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
OPA1
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O60313, P58281, Q2TA68
Gene Symbols:
OPA1
Immunogen:
Human OPA1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Hamster, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
1E8-1D9
Conjugate:
Unconjugated
Gene:
OPA1
Gene Alias:
1200011N24Rik; AI225888; AI847218; BERHS; Dynamin-like 120 kDa protein, form S1; Dynamin-like 120 kDa protein, mitochondrial; dynamin-like guanosine triphosphatase; EMBL:AAI11072.1}; hypothetical protein; KIAA0567; Large GTP-binding protein; largeG; lilr3; MGM1; mitochondrial dynamin-like GTPase; mitochondrial OPA1; mKIAA0567; MTDPS14; NPG; NTG; OPA1; opa1 {ECO:0000312; OPA1 mitochondrial dynamin like GTPase; OPA1, mitochondrial dynamin like GTPase; optic atrophy 1; optic atrophy 1 (autosomal dominant); optic atrophy 1 homolog; optic atrophy 1-like protein; optic atrophy protein 1; Optic atrophy protein 1 homolog; RCJMB04_1m16; RN protein
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
100751873, 171116, 4976, 524142, 74143
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: RANK
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O35305, Q9Y6Q6
Gene Symbols: TNFRSF11A
Immunogen: A fusion protein containing amino acid residues 326-616 of human RANK.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Avian, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone: 9A725
Conjugate: Unconjugated
Gene: TNFRSF11A
Gene Alias: CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 21934, 498206, 8792
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
RANK
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O35305, Q9Y6Q6
Gene Symbols:
TNFRSF11A
Immunogen:
A fusion protein containing amino acid residues 326-616 of human RANK.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Avian, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Clone:
9A725
Conjugate:
Unconjugated
Gene:
TNFRSF11A
Gene Alias:
CD265; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; Ly109; mRANK; ODFR; OFE; OPTB7; Osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; Rank; receptor activator of NF-kappaB; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; RGD1563614; TNF receptor superfamily member 11a; Tnfrsf11a; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily member 11a, NFKB activator; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
21934, 498206, 8792
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: IKK beta
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O14920, O88351, Q9QY78
Gene Symbols: Ikbkb
Immunogen: full-length human IKKbeta recombinant protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 10AG2
Conjugate: Unconjugated
Gene: Ikbkb
Gene Alias: AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 16150, 3551, 84351
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
IKK beta
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O14920, O88351, Q9QY78
Gene Symbols:
Ikbkb
Immunogen:
full-length human IKKbeta recombinant protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
10AG2
Conjugate:
Unconjugated
Gene:
Ikbkb
Gene Alias:
AI132552; AIM-1; FLJ40509; I-kappa-B kinase 2; I-kappa-B-kinase beta; Ikbkb; IKK[b]; IKK2; IKK-2; IKKB; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa-B kinase subunit beta; MGC131801; NFKBIKB; nuclear factor NF-kappa-B inhibitor kinase beta
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
16150, 3551, 84351
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: CD254 (RANK Ligand)
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% sodium azide
Gene Accession No.: O14788, O35235, Q9ESE2
Gene Symbols: TNFSF11
Immunogen: A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse RANKL was used as immunogen.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1 κ
Applications: ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 12A668
Conjugate: Unconjugated
Gene: TNFSF11
Gene Alias: CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 117516, 21943, 8600
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
CD254 (RANK Ligand)
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% sodium azide
Gene Accession No.:
O14788, O35235, Q9ESE2
Gene Symbols:
TNFSF11
Immunogen:
A bacterially expressed fusion protein containing amino acid residues 1-317 of mouse RANKL was used as immunogen.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG1 κ
Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone:
12A668
Conjugate:
Unconjugated
Gene:
TNFSF11
Gene Alias:
CD254; H-RANK-L; hRANKL2; Ly109l; M-Rank-L; ODF; OPG; OPG ligand; OPGL; OPTB2; Osteoclast differentiation factor; osteoprotegerin ligand; Rankl; rank-l; receptor activator of NF-kappaB ligand; receptor activator of nuclear factor kappa B ligand; receptor activator of nuclear factor kappa-B ligand; RP11-86N24.2; sOdf; srankl; TNF-related activation-induced cytokine; Tnfsf11; TNLG6B; Trance; tumor necrosis factor (ligand) superfamily member 11; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; Tumor necrosis factor ligand superfamily member 11, membrane form; Tumor necrosis factor ligand superfamily member 11, soluble form; tumor necrosis factor superfamily member 11; tumor necrosis factor-related activation-induced cytokine
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
117516, 21943, 8600
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid