PIMA527717

CaV1.2 Monoclonal Antibody (S57-46), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIMA527717-Each-of-1 In Stock ₹ 50,352.06

PIMA527717 - Each of 1

₹ 50,352.06

In Stock

Quantity

1

Base Price: ₹ 50,352.06

GST (18%): ₹ 9,063.371

Total Price: ₹ 59,415.431

Antigen

CaV1.2

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.

P15381, P22002, Q01815, Q13936

Gene Symbols

CACH2C, CACNA1C

Immunogen

Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Hamster, Human, Mouse, Rabbit, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

S57-46

Conjugate

Unconjugated

Gene

CACNA1C

Gene Alias

brain class C; CACB; CaCB receptor; CACB-receptor; CACH2; CACH2C; CACH3; Cacn2; CACN4; CACNA 1D; Cacna1c; CACNL1A1; CACNL1A2; calcium channel; calcium channel voltage-dependent alpha1c subunit; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; calcium channel, voltage-dependent, alpha 1C subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; calcium voltage-gated channel subunit alpha1 C; cardiac L-type calcium channel; Cav1.2; CCHL1A1; D930026N18Rik; DHP receptor; DHPR, alpha-1 subunit; I79_006562; long-NT; LQT8; LTCC; L-type calcium channel alpha-1 subunit; MBC; MELC-CC; MGC120730; Mouse brain class C; neuronal voltage-gated calcium channel alpha 1C subunit; Rat brain class C; RATIVS302; RBC; skeletal muscle-specific calcium channel; smooth muscle calcium channel blocker; Smooth muscle calcium channel blocker receptor; TS; unnamed protein product; voltage-dependent L-type Ca2+ channel alpha 1 subunit; Voltage-dependent L-type calcium channel subunit alpha-1C; Voltage-gated calcium channel subunit alpha Cav1.2; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100101555, 100144322, 100754788, 12288, 24239, 775

Content And Storage

-20°C

Form

Liquid

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Description

  • 1 μg/mL of MA5-27717 was sufficient for detection of Cav1.2 in 10 μg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.∣Detects approximately 240kDa (varies with cell background due to glycosylation)
  • CACNA1C encodes an alpha-1 subunit of a voltage-dependent calcium channel
  • Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization
  • The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell
  • The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio
  • There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts
  • The protein encoded by CACNA1C binds to and is inhibited by dihydropyridine
  • Alternative splicing results in many transcript variants encoding different proteins.

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Thermo Scientific

PIMA527717

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Antigen:
CaV1.2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P15381, P22002, Q01815, Q13936

Gene Symbols:
CACH2C, CACNA1C

Immunogen:
Fusion protein amino acids 1507-1733 (intracellular carboxyl terminus) of rabbit Cav1.2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Hamster, Human, Mouse, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
S57-46

Conjugate:
Unconjugated

Gene:
CACNA1C

Gene Alias:
brain class C; CACB; CaCB receptor; CACB-receptor; CACH2; CACH2C; CACH3; Cacn2; CACN4; CACNA 1D; Cacna1c; CACNL1A1; CACNL1A2; calcium channel; calcium channel voltage-dependent alpha1c subunit; calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit; calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle; calcium channel, voltage-dependent, alpha 1C subunit; calcium channel, voltage-dependent, L type, alpha 1C subunit; calcium voltage-gated channel subunit alpha1 C; cardiac L-type calcium channel; Cav1.2; CCHL1A1; D930026N18Rik; DHP receptor; DHPR, alpha-1 subunit; I79_006562; long-NT; LQT8; LTCC; L-type calcium channel alpha-1 subunit; MBC; MELC-CC; MGC120730; Mouse brain class C; neuronal voltage-gated calcium channel alpha 1C subunit; Rat brain class C; RATIVS302; RBC; skeletal muscle-specific calcium channel; smooth muscle calcium channel blocker; Smooth muscle calcium channel blocker receptor; TS; unnamed protein product; voltage-dependent L-type Ca2+ channel alpha 1 subunit; Voltage-dependent L-type calcium channel subunit alpha-1C; Voltage-gated calcium channel subunit alpha Cav1.2; voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100101555, 100144322, 100754788, 12288, 24239, 775

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527718

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Antigen:
HCN2

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
O88703, Q9JKA9, Q9UL51

Gene Symbols:
HCN2

Immunogen:
Fusion protein amino acids 761-863 of rat HCN2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Microarray, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
S71

Conjugate:
Unconjugated

Gene:
HCN2

Gene Alias:
BCNG2; BCNG-2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; Hac1; HAC-1; HCN2; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; hyperpolarization-activated cation channel 1; hyperpolarization-activated, cyclic nucleotide-gated K+ 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2; trls

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
114244, 15166, 610

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527719

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Antigen:
ATP7B

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P35670, Q64446, Q64535

Gene Symbols:
Atp7b

Immunogen:
Synthetic peptide amino acids 3-21 (cytoplasmic N-terminus) of human Copper-transporting ATPase2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
S62-29

Conjugate:
Unconjugated

Gene:
Atp7b

Gene Alias:
Atp7a; ATP7B; ATPase copper transporting beta; ATPase, Cu(2+)- transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide; ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease); copper pump 2; Copper-transporting ATPase 2; Hts; PINA; PINA gene, promoter; pineal night-specific ATPase; PWD; RP11-327P2.1; RP11-327P2.3; toxic milk; tx; WC1; WD; Wilson disease-associated protein; wilson disease-associated protein homolog; Wilson protein; Wnd; WND/140 kDa

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11979, 24218, 540

Content And Storage:
-20°C

Form:
Liquid

Img

Thermo Scientific

PIMA527720

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Antigen:
ATP7A

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4

Gene Accession No.:
P70705, Q04656, Q64430

Gene Symbols:
ATP7A

Immunogen:
Synthetic peptide amino acids 42-61 (cytoplasmic C-terminus) of human Copper- transporting ATPase1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
S60-4

Conjugate:
Unconjugated

Gene:
ATP7A

Gene Alias:
ATP 7A; ATP7A; ATPase copper transporting alpha; ATPase, Cu++ transporting, alpha polypeptide; copper pump 1; Copper-transporting ATPase 1; Cu++-transporting P-type ATPase; DSMAX; FLJ17790; MC 1; MC1; Menke; Menkes disease-associated protein; menkes disease-associated protein homolog; Menkes protein; Menkes syndrome; MK; MNK; OHS; OTTHUMP00000062077; SMAX3

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11977, 24941, 538

Content And Storage:
-20°C

Form:
Liquid