PIMA532132

p27 Kip1 Recombinant Rabbit Monoclonal Antibody (SU37-04), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA532132-Each-of-1 In Stock ₹ 45,646.26

PIMA532132 - Each of 1

₹ 45,646.26

In Stock

Quantity

1

Base Price: ₹ 45,646.26

GST (18%): ₹ 8,216.327

Total Price: ₹ 53,862.587

Antigen

p27 Kip1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.

P46527

Gene Symbols

Cdkn1b

Immunogen

Synthetic peptide within Human p27 KIP 1 aa 149-198

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Rat

Product Type

Antibody

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone

SU37-04

Conjugate

Unconjugated

Gene

Cdkn1b

Gene Alias

AA408329, AI843786, Cdki1b, CDKN1B, CDKN4, CDN1B, cyclin dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor 1B (p27 Kip1), Cyclin-dependent kinase inhibitor 1B (p27, Kip1), cyclin-dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor p27 Kip1, cyclin-dependent kinase inhibitor p27/Kip1, KIP1, MEN1B, MEN4, p27, P27 CDKN1B, p27(KIP1), p27Kip1

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

1027, 83571

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
  • The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
  • Then, individual clones are screened to select the best candidates for production
  • The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
  • p27 Kip1 functions as a negative regulator of G1 mouse expression and has been proposed to function as a possible mediator of TGFb induced G1 arrest
  • p27 Kip1 is an important regulator of cell cycle progression, a potent inhibitor of cyclin E- and cyclin A-CDK2 complexes
  • p27 Kip1 forms a complex with cyclin type D-CDK4 complexes and is involved in the assembly, stability, and modulation of CCND1-CDK4 complex activation
  • p27 Kip1 acts either as an inhibitor or an activator of cyclin type D-CDK4 complexes depending on its phosphorylation state and/or stoichometry
  • p27 Kip1 has a molecular weight of approximately 27kDa and the degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Compare Similar Items

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Img

Thermo Scientific

PIMA532132

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Antigen:
p27 Kip1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P46527

Gene Symbols:
Cdkn1b

Immunogen:
Synthetic peptide within Human p27 KIP 1 aa 149-198

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU37-04

Conjugate:
Unconjugated

Gene:
Cdkn1b

Gene Alias:
AA408329, AI843786, Cdki1b, CDKN1B, CDKN4, CDN1B, cyclin dependent kinase inhibitor 1B, cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor 1B (p27 Kip1), Cyclin-dependent kinase inhibitor 1B (p27, Kip1), cyclin-dependent kinase inhibitor p27, Cyclin-dependent kinase inhibitor p27 Kip1, cyclin-dependent kinase inhibitor p27/Kip1, KIP1, MEN1B, MEN4, p27, P27 CDKN1B, p27(KIP1), p27Kip1

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1027, 83571

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532133

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Antigen:
p16INK4a

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P42771

Gene Symbols:
CDKN2A

Immunogen:
Synthetic peptide within Human p16INK4A aa 107-156

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU0702

Conjugate:
Unconjugated

Gene:
CDKN2A

Gene Alias:
Alternative reading frame, Arf, ARF-INK4a, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16-INK4, CDK4I, CDKN2, Cdkn2a, cdkn2a {ECO:0000312, cell cycle inhibitor, cell cycle negative regulator beta, cell cycle regulator, CMM2, Cyclin dependent kinase 4 inhibitor A, cyclin dependent kinase inhibitor 2A, Cyclin dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase 4 inhibitor A, Cyclin-dependent kinase inhibitor 2A, cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2A (p16, inhibits CDK4), cyclin-dependent kinase inhibitor 2a p16Ink4a, cyclin-dependent kinase inhibitor 2a p19Arf, cyclin-dependent kinase inhibitor 2A, isoform 1, cyclin-dependent kinase inhibitor 2A, isoform 2, cyclin-dependent kinase inhibitor 2A, isoform 3, cyclin-dependent kinase inhibitor 2A, isoforms 1/2, cyclin-dependent kinase inhibitor protein, EMBL:AAL76336.1, ECO:0000312, EMBL:AAL76338.1, ECO:0000312, HGNC:1787, inhibits CDK4, INK4, INK4A, Ink4a/Arf, INK4a-ARF, isoforms 1/2/3, Melanoma p16 inhibits CDK4, mitochondrial smARF, MLM, MTS1, MTS-1, Multiple tumor suppressor 1, P14, P14 P16, P14ARF, p16, p16(INK4a), p16Cdkn2a, P16INK4, p16-INK4, p16INK4a, p16-INK4a, P19, P19 TP16, p19<ARF>, P19ARF, Pctr1, RGD:2323}, TP16, Tumor suppressor ARF

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
1029

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532136

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Antigen:
MYLK

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
Q15746, Q6PDN3

Gene Symbols:
MYLK

Immunogen:
Synthetic peptide within Human MYLK aa 1,865-1,914

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot, Western Blot

Clone:
SU40-06

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
107589, 288057, 4638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

PIMA532137

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Antigen:
Caspase 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide, pH 7.4

Gene Accession No.:
P29452, P29466, P43527

Gene Symbols:
CASP1

Immunogen:
Recombinant protein within Human Caspase-1 aa 213-404

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Western Blot, Western Blot

Clone:
SU40-07

Conjugate:
Unconjugated

Gene:
CASP1

Gene Alias:
CASP1, CASP-1, CASP1 nirs variant 1, caspase 1, caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase), Caspase1, caspase-1, Caspase-1 subunit p10, Caspase-1 subunit p20, ICE, IL-1 beta-converting enzyme, IL-1B converting enzyme, IL1BC, IL-1BC, IL1BCE, IL1B-convertase, interleukin 1 beta-converting enzyme, interleukin 1, beta, convertase, interleukin 1-B converting enzyme, Interleukin 1beta converting enzyme, interleukin-1 beta convertase, Interleukin-1 beta-converting enzyme, p45

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
12362, 25166, 834

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid