PIMA533062
Phospho-gamma-H2AX (Ser139) Recombinant Rabbit Monoclonal Antibody (RM224), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA533062-Each-of-1 | In Stock | ₹ 48,811.98 |
PIMA533062 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,811.98
GST (18%): ₹ 8,786.156
Total Price: ₹ 57,598.136
Antigen
Phospho-gamma-H2AX (Ser139)
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.
P16104, P27661
Gene Symbols
H2AX
Immunogen
A phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
Quantity
100 μg
Primary or Secondary
Primary
Target Species
All species, Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Applications
ELISA, Immunocytochemistry, Luminex, Western Blot, Western Blot
Clone
RM224
Conjugate
Unconjugated
Gene
H2AX
Gene Alias
gamma H2A X, gamma H2A.X, gamma-H2A.X, gh2ax
Host Species
Rabbit
Purification Method
Protein A
Regulatory Status
RUO
Gene ID (Entrez)
15270, 3014, 500987
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- Specificity: reacts to Histone H2A.X only when phosphorylated at serine 139
- No cross reactivity with other phosphorylated histones
- Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems
- The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits
- Then, individual clones are screened to select the best candidates for production
- The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire
- H2AX is a variant of the H2A protein family and is a component of the histone octomer in nucleosomes
- H2AX is phosphorylated by kinases such as ataxia telangiectasia mutated (ATM) and ATM-Rad3-related (ATR) in the PI3K pathway
- Gamma-H2AX is the first step in recruiting and localizing DNA repair proteins
- DSBs can be induced by mechanisms such as ionizing radiation or cytotoxic agents and subsequently, gamma-H2AX foci quickly form
- These foci represent the DSBs in a 1:1 manner and can be used as a biomarker for damage
- The visualization of gamma-H2AX by can allow the assessment of DNA damage, related DNA damage proteins and DNA repair
- Gamma-H2AX has applications in the detection of genomic damage caused by cytotoxic chemical agents and environmental and physical damage.
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Antigen: Phospho-gamma-H2AX (Ser139)
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: A phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: All species, Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: ELISA, Immunocytochemistry, Luminex, Western Blot, Western Blot
Clone: RM224
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: gamma H2A X, gamma H2A.X, gamma-H2A.X, gh2ax
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: -20°C
Form: Liquid
Antigen:
Phospho-gamma-H2AX (Ser139)
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
A phospho-peptide corresponding to Phospho-Histone H2AX (Ser139).
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
All species, Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
ELISA, Immunocytochemistry, Luminex, Western Blot, Western Blot
Clone:
RM224
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
gamma H2A X, gamma H2A.X, gamma-H2A.X, gh2ax
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
-20°C
Form:
Liquid
Antigen: Cytokeratin 5
Classification: Recombinant Monoclonal
Concentration: 0.04 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P13647
Gene Symbols: KRT5
Immunogen: A peptide corresponding to the C-terminus of Human Cytokeratin 5.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM226
Conjugate: Unconjugated
Gene: KRT5
Gene Alias: 3300001P10Rik, 58 kDa cytokeratin, alpha keratin, AW146334, CK5, CK-5, ckii, ckii protein, cytokeratin 5, cytokeratin-5, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K5, keratin 5, keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5, type II, keratin complex 2, basic, gene 5, keratin type II, tail domain, keratin, type II cytoskeletal 5, keratin, type II cytoskeletal 5, keratin 5, keratin-5, Krt2-5, KRT5, KRT5A, Sak57, Tfip8, tuftelin interacting protein 8, type II alpha-keratin IIA, type II cytokeratin, type-II keratin Kb5, wu:fb02h09, wu:fj02d02, wu:fk78b12, zfCKII
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3852
Content And Storage: -20°C
Form: Liquid
Antigen:
Cytokeratin 5
Classification:
Recombinant Monoclonal
Concentration:
0.04 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P13647
Gene Symbols:
KRT5
Immunogen:
A peptide corresponding to the C-terminus of Human Cytokeratin 5.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM226
Conjugate:
Unconjugated
Gene:
KRT5
Gene Alias:
3300001P10Rik, 58 kDa cytokeratin, alpha keratin, AW146334, CK5, CK-5, ckii, ckii protein, cytokeratin 5, cytokeratin-5, DDD, DDD1, EBS2, epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types, K5, keratin 5, keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types), keratin 5, type II, keratin complex 2, basic, gene 5, keratin type II, tail domain, keratin, type II cytoskeletal 5, keratin, type II cytoskeletal 5, keratin 5, keratin-5, Krt2-5, KRT5, KRT5A, Sak57, Tfip8, tuftelin interacting protein 8, type II alpha-keratin IIA, type II cytokeratin, type-II keratin Kb5, wu:fb02h09, wu:fj02d02, wu:fk78b12, zfCKII
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3852
Content And Storage:
-20°C
Form:
Liquid
Antigen: NFkB p50/p105
Classification: Recombinant Monoclonal
Concentration: 0.1 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P19838
Gene Symbols: NFKB1
Immunogen: A peptide corresponding to residues in the human NFkappa-B p105 subunit and p50 subunit.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM299
Conjugate: Unconjugated
Gene: NFKB1
Gene Alias: CVID12, DKFZp686C01211, DNA-binding factor KBF1, EBP-1, KBF1, MGC54151, NF kappaB1, NF KB, NFkappaB, NF-kappaB, NF-kappa-B, NF-kappaB p50, NF-kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappabeta, NF-kB, NFKB1, NF-KB1, NFKB-p105, NFKB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 1, nuclear factor kappa-B DNA binding subunit, nuclear factor kappaB p50, nuclear factor NF-kappa-B p105 subunit, Nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, nuclear factor-kappaB p50, p105, p50, p50 subunit of NF kappaB, p50 subunit of NF-kappaB, p50/p105
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 4790
Content And Storage: -20°C
Form: Liquid
Antigen:
NFkB p50/p105
Classification:
Recombinant Monoclonal
Concentration:
0.1 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P19838
Gene Symbols:
NFKB1
Immunogen:
A peptide corresponding to residues in the human NFkappa-B p105 subunit and p50 subunit.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM299
Conjugate:
Unconjugated
Gene:
NFKB1
Gene Alias:
CVID12, DKFZp686C01211, DNA-binding factor KBF1, EBP-1, KBF1, MGC54151, NF kappaB1, NF KB, NFkappaB, NF-kappaB, NF-kappa-B, NF-kappaB p50, NF-kappaB1, NF-kappa-B1 p84/NF-kappa-B1 p98, NF-kappabeta, NF-kB, NFKB1, NF-KB1, NFKB-p105, NFKB-p50, nuclear factor, nuclear factor kappa b, nuclear factor kappa B subunit 1, nuclear factor kappa-B DNA binding subunit, nuclear factor kappaB p50, nuclear factor NF-kappa-B p105 subunit, Nuclear factor NF-kappa-B p50 subunit, nuclear factor of kappa light chain gene enhancer in B-cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105, nuclear factor-kappaB p50, p105, p50, p50 subunit of NF kappaB, p50 subunit of NF-kappaB, p50/p105
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
4790
Content And Storage:
-20°C
Form:
Liquid
Antigen: CD21
Classification: Recombinant Monoclonal
Concentration: 0.2 mg/mL
Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.: P20023
Gene Symbols: CR2
Immunogen: A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: RM372
Conjugate: Unconjugated
Gene: CR2
Gene Alias: C3b/C4b receptor, C3-binding protein, C3BR, C3DR, C4BR, CD21, CD35, CD35 antigen, cell surface receptor for C3d, complement C3b/C4b receptor 1 (Knops blood group), complement C3d receptor, Complement C3d receptor (C3DR), complement C3d receptor 2, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3d/Epstein Barr virus) receptor 2, complement component 3b/4b receptor 1 (Knops blood group), complement component 3d receptor 2, complement component receptor 2, complement receptor 1 long isoform, complement receptor 2, complement receptor type 1, complement receptor type 1-like protein, complement receptor type 2, Complement Receptor type 2 (CR2), CR, CR1, Cr-1, CR1-L, Cr2, Cr-2, CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, expressed in B lymphocytes, KN, Knops blood group antigen, LOW QUALITY PROTEIN: complement receptor type 1, SLEB9
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 1380
Content And Storage: -20°C
Form: Liquid
Antigen:
CD21
Classification:
Recombinant Monoclonal
Concentration:
0.2 mg/mL
Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide
Gene Accession No.:
P20023
Gene Symbols:
CR2
Immunogen:
A peptide corresponding to the C-terminus of human CD21 (Complement receptor type 2).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
RM372
Conjugate:
Unconjugated
Gene:
CR2
Gene Alias:
C3b/C4b receptor, C3-binding protein, C3BR, C3DR, C4BR, CD21, CD35, CD35 antigen, cell surface receptor for C3d, complement C3b/C4b receptor 1 (Knops blood group), complement C3d receptor, Complement C3d receptor (C3DR), complement C3d receptor 2, complement component (3b/4b) receptor 1 (Knops blood group), complement component (3d/Epstein Barr virus) receptor 2, complement component 3b/4b receptor 1 (Knops blood group), complement component 3d receptor 2, complement component receptor 2, complement receptor 1 long isoform, complement receptor 2, complement receptor type 1, complement receptor type 1-like protein, complement receptor type 2, Complement Receptor type 2 (CR2), CR, CR1, Cr-1, CR1-L, Cr2, Cr-2, CVID7, EBV receptor, EBV-R, Epstein-Barr virus receptor, EVBR, expressed in B lymphocytes, KN, Knops blood group antigen, LOW QUALITY PROTEIN: complement receptor type 1, SLEB9
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
1380
Content And Storage:
-20°C
Form:
Liquid