PIPA5102856

Phospho-ULK1 (Ser556) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5102856-Each-of-1 In Stock ₹ 44,705.10

PIPA5102856 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-ULK1 (Ser556)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ULK1

Gene Alias

APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22241, 360827, 8408

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O70405, O75385

Gene Symbols

ULK1

Immunogen

A synthesized peptide derived from human ULK1(Accession O75385), corresponding to amino acid residues around phosphorylated Ser556.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of ULK1 only when phosphorylated at S556
  • ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation
  • The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein
  • Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR
  • ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy
  • Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein
  • ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5102856

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Antigen:
Phospho-ULK1 (Ser556)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ULK1

Gene Alias:
APG1; ATG 1; ATG1; ATG1 autophagy related 1 homolog; ATG1A; AU041434; Autophagy-related protein 1 homolog; C. elegans; EC:2.7.11.1; FLJ38455; hATG1; KIAA0722; mKIAA0722; Serine/threonine-protein kinase ULK1; serine/threonine-protein kinase Unc51.1; ULK 1; Ulk1; UNC 51; UNC51; unc-51 like autophagy activating kinase 1; unc-51 like kinase 1; Unc51.1; unc-51-like kinase 1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22241, 360827, 8408

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O70405, O75385

Gene Symbols:
ULK1

Immunogen:
A synthesized peptide derived from human ULK1(Accession O75385), corresponding to amino acid residues around phosphorylated Ser556.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5102858

--


Antigen:
USP22

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
USP22

Gene Alias:
AI427806; Deubiquitinating enzyme 22; KIAA1063; Ubiquitin carboxyl-terminal hydrolase 22; ubiquitin specific peptidase 22; ubiquitin specific protease 22; ubiquitin thioesterase 22; ubiquitin thiolesterase 22; ubiquitin-specific processing protease 22; ubiquitin-specific-processing protease 22; Usp22; USP3L

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
216825, 23326, 303201

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q5DU02, Q9UPT9

Gene Symbols:
USP22

Immunogen:
A synthesized peptide derived from human USP22(Accession Q9UPT9), corresponding to amino acid residues K122-T172.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5102859

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Antigen:
Phospho-ErbB3 (Tyr1289)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3; avian erythroblastosis oncogene B 3 receptor; C76256; c-erbB3; c-erbB-3; C-errB-3; erb-b2 receptor tyrosine kinase 3; ERBB3; Erbb-3; Erbb3r; erbB3-S; glial growth factor receptor; HER3; human epidermal growth factor receptor 3; LCCS2; MDA BF 1; MDA-BF-1; MGC88033; nuc-ErbB3; p180 ErbB3; p180-ErbB3; p45 sErbB3; p45-sErbB3; p85 sErbB3; p85-sErbB3; proto-oncogene-like protein c-ErbB-3; receptor tyrosine kinase; receptor tyrosine-protein kinase erbB-3; receptor tyrosine-protein kinase erbB-3; LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3; tyrosine kinase-type cell surface receptor HER3; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3; v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13867, 2065, 29496

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P21860, Q61526, Q62799

Gene Symbols:
ERBB3

Immunogen:
A synthesized peptide derived from human ERBB3(Accession P21860), corresponding to amino acid residues around phosphorylated Tyr1289.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5102861

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Antigen:
ASIP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ASIP

Gene Alias:
agouti signaling protein; agouti signaling protein, nonagouti homolog; agouti switch protein; Agouti-signaling protein; AGSW; AGTI; AGTIL; ASIP; ASP; nonagouti homolog; SHEP9

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
434

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P42127

Gene Symbols:
ASIP

Immunogen:
A synthesized peptide derived from human ASIP(Accession P42127), corresponding to amino acid residues K81-N131.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG