PIPA5143626

Phospho-CtIP (Ser327) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143626-Each-of-1 In Stock ₹ 39,828.18

PIPA5143626 - Each of 1

₹ 39,828.18

In Stock

Quantity

1

Base Price: ₹ 39,828.18

GST (18%): ₹ 7,169.072

Total Price: ₹ 46,997.252

Antigen

Phospho-CtIP (Ser327)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Rbbp8

Gene Alias

9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

5932

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.25 mg/mL

Formulation

10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q99708

Gene Symbols

Rbbp8

Immunogen

Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser327 of human CtIP, conjugated to keyhole limpet hemocyanin (KLH).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Specific for endogenous levels of the ∽100 kDa CtIP protein phosphorylated at Ser327
  • Immunolabeling is completely eliminated by treatment with lambda-phosphatase
  • CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
  • Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
  • This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
  • Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.

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Thermo Scientific

PIPA5143626

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Antigen:
Phospho-CtIP (Ser327)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rbbp8

Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; CtIP; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; RBBP8; RBBP-8; retinoblastoma binding protein 8; retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
5932

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q99708

Gene Symbols:
Rbbp8

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser327 of human CtIP, conjugated to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

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PIPA5143627

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Antigen:
Phospho-IRE1 alpha (Ser724)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
78943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
∽0.25 mg/mL

Formulation:
10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9EQY0

Gene Symbols:
ERN1

Immunogen:
Synthetic phosphopeptide corresponding to amino acid residues surrounding the phospho Ser724 of mouse IRE1, conjugated to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

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PIPA5143628

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Antigen:
Ki-67

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mki67

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Host Species:
Chicken

Purification Method:
IgY fraction

Regulatory Status:
RUO

Gene ID (Entrez):
17345, 291234, 4288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
∽20.0 mg/mL

Formulation:
PBS with 10mM sodium azide

Gene Accession No.:
E9PVX6, P46013

Gene Symbols:
Mki67

Immunogen:
Recombinant human ki-67 protein expressed in and purified from E. Coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA514363

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Antigen:
EN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EN2

Gene Alias:
AUTS1; BB131122; EN2; En-2; engrailed 2; engrailed homeobox 2; engrailed homolog 2; engrailed-2; homeobox protein en-2; Homeobox protein engrailed-2; hu-En-2; mo-En-2; RGD1561842

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13799, 2020

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P09066, P19622

Gene Symbols:
EN2

Immunogen:
KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human EN2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid