PIPA5143627

Phospho-IRE1 alpha (Ser724) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143627-Each-of-1 In Stock ₹ 14,442.53

PIPA5143627 - Each of 1

₹ 14,442.53

In Stock

Quantity

1

Base Price: ₹ 14,442.53

GST (18%): ₹ 2,599.655

Total Price: ₹ 17,042.185

Antigen

Phospho-IRE1 alpha (Ser724)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERN1

Gene Alias

9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

78943

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

∽0.25 mg/mL

Formulation

10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q9EQY0

Gene Symbols

ERN1

Immunogen

Synthetic phosphopeptide corresponding to amino acid residues surrounding the phospho Ser724 of mouse IRE1, conjugated to keyhole limpet hemocyanin (KLH).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • Specific for endogenous levels of the ∽130 kDa GluR1 protein phosphorylated at Ser724
  • Immunolabeling is completely eliminated by treatment with lambda-phosphatase
  • ERN1 serine/threonine kinase or endoplasmic reticulum to nucleus signaling 1 is the ER to nucleus signaling 1 protein, a human homologue of the yeast Ire1 gene product which possesses intrinsic kinase activity and an endoribonuclease activity and it is important in endoplasmic reticulum-based stress signals
  • ERN1 controls IRE1 proteolysis in mammalian cells
  • ERN1 has a critical function in extraembryonic cells that is essential for fetal viability
  • Specifically, IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator
  • Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER
  • Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5143627

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Antigen:
Phospho-IRE1 alpha (Ser724)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERN1

Gene Alias:
9030414B18Rik; AI225830; C85377; endoplasmic reticulum (ER) to nucleus signalling 1; endoplasmic reticulum to nucleus signaling 1; endoplasmic reticulum to nucleus signalling 1; endoplasmic reticulum-to-nucleus signaling 1; Endoribonuclease; ER to nucleus signalling 1; ERN1; FLJ30999; hIRE1p; inositol-requiring 1; inositol-requiring 1 alpha; inositol-requiring enzyme 1; inositol-requiring protein 1; IRE1; IRE1a; IRE1a antibody; Ire1alpha; Ire1-alpha; Ire1p; IRE1p antibody; MGC163277; MGC163279; protein kinase/endoribonuclease; RGD1559716; Serine/threonine-protein kinase; Serine/threonine-protein kinase/endoribonuclease IRE1; serine/threonine-protein kinase/endoribonuclease IRE1-like

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
78943

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
∽0.25 mg/mL

Formulation:
10mM HEPES with 100μg/mL BSA, 150mM NaCl, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q9EQY0

Gene Symbols:
ERN1

Immunogen:
Synthetic phosphopeptide corresponding to amino acid residues surrounding the phospho Ser724 of mouse IRE1, conjugated to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

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PIPA5143628

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Antigen:
Ki-67

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mki67

Gene Alias:
antigen identified by monoclonal antibody Ki 67; antigen identified by monoclonal antibody Ki-67; Antigen identified by monoclonal antibody Ki-67 homolog; Antigen KI-67; Antigen KI-67 homolog; antigen KI-67; proliferation marker protein Ki-67; antigen KI-67-like; cb31; D630048A14Rik; I79_022666; Ki67; Ki-67; KIA; LOW QUALITY PROTEIN: proliferation marker protein Ki-67; marker of proliferation Ki-67; MIB-; MIB-1; Mki67; PPP1R105; Proliferation marker protein Ki-67; proliferation-related Ki-67 antigen; protein phosphatase 1, regulatory subunit 105; RP11-380J17.2; sb:cb31; si:ch211-250b22.7; unnamed protein product; wu:fa11g09; wu:fb57a07; wu:fi14e05

Host Species:
Chicken

Purification Method:
IgY fraction

Regulatory Status:
RUO

Gene ID (Entrez):
17345, 291234, 4288

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgY

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
∽20.0 mg/mL

Formulation:
PBS with 10mM sodium azide

Gene Accession No.:
E9PVX6, P46013

Gene Symbols:
Mki67

Immunogen:
Recombinant human ki-67 protein expressed in and purified from E. Coli.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

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PIPA514363

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Antigen:
EN2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EN2

Gene Alias:
AUTS1; BB131122; EN2; En-2; engrailed 2; engrailed homeobox 2; engrailed homolog 2; engrailed-2; homeobox protein en-2; Homeobox protein engrailed-2; hu-En-2; mo-En-2; RGD1561842

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography, Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13799, 2020

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
2 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P09066, P19622

Gene Symbols:
EN2

Immunogen:
KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human EN2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Liquid

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PIPA5143630

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Antigen:
Phospho-MECP2 (Ser80)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mecp2

Gene Alias:
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species:
Rabbit

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
17257, 29386, 4204

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
Lot-Specific

Formulation:
Serum with no preservative

Gene Accession No.:
P51608, Q00566, Q9Z2D6

Gene Symbols:
Mecp2

Immunogen:
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser80 of human MeCP2, conjugated to keyhole limpet hemocyanin (KLH).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid