PIPA5143741
Phospho-PDPK1 (Ser241) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143741-Each-of-1 | In Stock | ₹ 44,106.18 |
PIPA5143741 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,106.18
GST (18%): ₹ 7,939.112
Total Price: ₹ 52,045.292
Antigen
Phospho-PDPK1 (Ser241)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pdpk1
Gene Alias
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18607, 5170, 81745
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunohistochemistry (Frozen), Western Blot
Concentration
0.25 mg/mL
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
O15530, O55173, Q9Z2A0
Gene Symbols
Pdpk1
Immunogen
Phospho-PDK1 (Ser-241) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding serine 241 in human PDK1. This sequence is highly conserved in rat and mouse PDK1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Related Products
Description
- The purified antibody detects a 65 kDa* protein corresponding to the apparent molecular mass of PDK1 on SDS-PAGE immunoblots of human MDA-MB-435 cells treated with EGF, but not in untreated cells
- PDK1 (Ser-241) reactivity was also observed by immunohistochemistry in human breast carcinoma tissue
- PDPK1 (3 Phosphoinositide Dependent Protein Kinase 1) phosphorylates AGC kinases
- PDPK1 activates conventional PKC and PKC zeta through phosphorylation of critical threonine residues in the activation loop
- PDPK1 also phosphorylates Protein Kinase B (PKB) at threonine 308 in the presence of phosphatidylinositol-3,4,5-trisphosphate
- Active Akt inactivates Glycogen Synthase Kinase 3 (GSK3), eventually leading to the dephosphorylation and activation of glycogen synthase, and the stimulation of glycogen synthesis
- Because of the role that PDPK1 plays in insulin-induced glycogen synthesis and PKC activation, it is a potentially important target for metabolic drug research.
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Antigen: Phospho-PDPK1 (Ser241)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pdpk1
Gene Alias: 3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18607, 5170, 81745
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunohistochemistry (Frozen), Western Blot
Concentration: 0.25 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O15530, O55173, Q9Z2A0
Gene Symbols: Pdpk1
Immunogen: Phospho-PDK1 (Ser-241) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding serine 241 in human PDK1. This sequence is highly conserved in rat and mouse PDK1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-PDPK1 (Ser241)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pdpk1
Gene Alias:
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18607, 5170, 81745
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunohistochemistry (Frozen), Western Blot
Concentration:
0.25 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O15530, O55173, Q9Z2A0
Gene Symbols:
Pdpk1
Immunogen:
Phospho-PDK1 (Ser-241) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding serine 241 in human PDK1. This sequence is highly conserved in rat and mouse PDK1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Phosphotyrosine
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Pdpk1
Gene Alias: Phosphotyrosine; pTyr; pY
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18607, 5170, 81745
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O15530, O55173, Q9Z2A0
Gene Symbols: __
Immunogen: Anti-Phosphotyrosine was generated from a panel of phosphotyrosine-containing peptide immunogens designed from human protein sequences. All peptide sequences used are highly conserved phosphotyrosine motifs.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Multi-species, Mouse, Rat
Form: Liquid
Antigen:
Phosphotyrosine
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Pdpk1
Gene Alias:
Phosphotyrosine; pTyr; pY
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18607, 5170, 81745
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O15530, O55173, Q9Z2A0
Gene Symbols:
__
Immunogen:
Anti-Phosphotyrosine was generated from a panel of phosphotyrosine-containing peptide immunogens designed from human protein sequences. All peptide sequences used are highly conserved phosphotyrosine motifs.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Multi-species, Mouse, Rat
Form:
Liquid
Antigen: Phospho-PLCG1 (Tyr775)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLCG1
Gene Alias: 1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18803, 25738, 5335
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P10686, P19174, Q62077
Gene Symbols: PLCG1
Immunogen: PLCgamma1 (Tyr-775) synthetic peptide (coupled to carrier protein) corresponding to amino acids around tyrosine 775 in human PLCgamma1. This sequence has high homology to the conserved site in rat and mouse PLCgamma1, and has low homology to PLCgamma2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Phospho-PLCG1 (Tyr775)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLCG1
Gene Alias:
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; AI894140; Cded; cell differentiation and embryonic development; EC 3.1.4.11; inositoltrisphosphohydrolase; monophosphatidylinositol phosphodiesterase; NCKAP3; OTTHUMP00000178982; phosphatidylinositol phospholipase C; phosphoinositidase C; phosphoinositide phospholipase C; phosphoinositide phospholipase C-gamma-1; phospholipase C gamma 1; phospholipase C, gamma 1; phospholipase C, gamma 1 (formerly subtype 148); phospholipase C-1; phospholipase C-148; Phospholipase C2; phospholipase C-gamma-1; Phospholipase C-II; PLC gamma1; PLC1; Plc-1; PLC148; PLC-148; PLC2I; Plcg1; Plcg-1; PLCgamma1; Plc-gamma1; PLC-gamma-1; PLC-II; PPLCA; triphosphoinositide phosphodiesterase
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18803, 25738, 5335
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P10686, P19174, Q62077
Gene Symbols:
PLCG1
Immunogen:
PLCgamma1 (Tyr-775) synthetic peptide (coupled to carrier protein) corresponding to amino acids around tyrosine 775 in human PLCgamma1. This sequence has high homology to the conserved site in rat and mouse PLCgamma1, and has low homology to PLCgamma2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Antigen: Plexin-A1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PLXNA1
Gene Alias: 2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18844, 362398, 5361
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P70206, Q9UIW2
Gene Symbols: PLXNA1
Immunogen: Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the N-terminal half of the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Antigen:
Plexin-A1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PLXNA1
Gene Alias:
2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18844, 362398, 5361
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P70206, Q9UIW2
Gene Symbols:
PLXNA1
Immunogen:
Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the N-terminal half of the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid