PIPA517591

FAK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517591-Each-of-1 In Stock ₹ 50,565.96

PIPA517591 - Each of 1

₹ 50,565.96

In Stock

Quantity

1

Base Price: ₹ 50,565.96

GST (18%): ₹ 9,101.873

Total Price: ₹ 59,667.833

Antigen

FAK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PTK2

Gene Alias

CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100170770, 102167153, 14083, 25614, 506270, 5747

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

31 μg/mL

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

O35346, P34152, Q05397

Gene Symbols

PTK2

Immunogen

Synthetic peptide corresponding to residues surrounding amino acid 710 of human FAK

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Bovine, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA517733

--

Img

Thermo Scientific

PIPA517632

--

Img

Thermo Scientific

PIPA517785

--

Img

Thermo Scientific

PIPA517798

--

Img

Thermo Scientific

PIPA517552

--

Img

Thermo Scientific

PIPA517823

--

Img

Thermo Scientific

PIPA517551

--

Img

Thermo Scientific

PIPA517781

--

Description

  • It is not recommended to aliquot this antibody
  • This antibody is not cross-reactive with other proteins
  • Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
  • FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
  • FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
  • Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
  • Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
  • In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
  • In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
  • Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA517591

--


Antigen:
FAK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PTK2

Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100170770, 102167153, 14083, 25614, 506270, 5747

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
31 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O35346, P34152, Q05397

Gene Symbols:
PTK2

Immunogen:
Synthetic peptide corresponding to residues surrounding amino acid 710 of human FAK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Mouse, Non-human Primate, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517593

--


Antigen:
Phospho-IKK alpha/beta (Ser176, Ser180)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ikbkb

Gene Alias:
AI132552; AI256658; AIM-1; CHUK; Chuk1; component of inhibitor of nuclear factor kappa B kinase complex; conserved helix-loop-helix ubiquitous kinase; EC 2.7.11.10; Fbx24; Fbxo24; I kappa B kinase 1; i kappa-B kinase alpha; IkappaB kinase; I-kappa-B kinase 1; I-kappa-B kinase 2; IkappaB kinase alpha; I-kappa-B kinase alpha; I-kappa-B kinase-alpha; I-kappa-B-kinase beta; IkB kinase alpha subunit; IkB kinase-alpha; IkB kinase-beta; ikBKA; Ikbkb; IKK alpha; IKK[b]; IKK1; IKK2; IKK-2; IKKA; IKK-A; IKK-a kinase; IKK-alpha; Ikkb; IKK-B; IKKbeta; IKK-beta; IMD15; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta; inhibitor of kappaB kinase beta; inhibitor of nuclear factor kappa B kinase beta subunit; inhibitor of nuclear factor kappa B kinase subunit beta; inhibitor of nuclear factor kappa-B kinase subunit alpha; Inhibitor of nuclear factor kappa-B kinase subunit beta; NFKBIKA; NFKBIKB; Nuclear factor NFkappaB inhibitor kinase alpha; nuclear factor NF-kappa-B inhibitor kinase alpha; Nuclear factor NF-kappa-B inhibitor kinase beta; TCF16; TCF-16; TCF17; Transcription factor 16

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1147, 12675, 16150, 309361, 3551, 84351

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O14920, O15111, O88351, Q60680, Q9QY78

Gene Symbols:
CHUK, Ikbkb

Immunogen:
Phosphopeptide corresponding to a region surrounding pSer177/181 of IKKβ

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517597

--


Antigen:
Phospho-PBK (Thr9)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PBK

Gene Alias:
2810434B10Rik; AW538537; Cancer/testis antigen 84; CT84; D14Ertd732e; epididymis luminal protein 164; HEL164; Lymphokine-activated killer T-cell-originated protein kinase; MAPKK-like protein kinase; Nori-3; PBK; PDZ binding kinase; PDZ-binding kinase; serine/threonine protein kinase; spermatogenesis-related protein kinase; SPK; T-LAK cell-originated protein kinase; TOPK

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
55872

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
__

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
Q96KB5

Gene Symbols:
PBK

Immunogen:
Synthetic phosphopeptide corresponding to amino acids around pThr9 of human PBK/TOPK

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA517599

--


Antigen:
PABP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PABPC1

Gene Alias:
Cytoplasmic poly(A)-binding protein 1-A; ePAB; hypothetical protein; PAB1; pabp; PABP 1; Pabp1; PABP-1; PABP-1A; PABP-1-A; PABP-A; Pabpc1; pabpc1.L; pabpc1.S; pabpc1a; pabpc1-a; pabpc1a protein; pabpc1-b; pabpc2; PabpI; PABPL1; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1 L homeolog; poly(A) binding protein, cytoplasmic 1 S homeolog; poly(A) binding protein, cytoplasmic 1a; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1A; poly(A)-binding protein 1-A; polyadenylate-binding protein 1; Polyadenylate-binding protein 1A; Polyadenylate-binding protein 1-A; polyadenylate-binding protein 1A; poly(A) binding protein, cytoplasmic 1a; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; XELAEV_18033915mg; xPABP1-A; zgc:109879

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171350, 18458, 26986

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Western Blot

Concentration:
74 μg/mL

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P11940, P29341, Q9EPH8

Gene Symbols:
PABPC1

Immunogen:
Synthetic peptide corresponding to amino acids at the amino-terminus of human PABP1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG