PIPA517733
Phospho-FAK (Tyr925) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517733-Each-of-1 | In Stock | ₹ 44,362.86 |
PIPA517733 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,362.86
GST (18%): ₹ 7,985.315
Total Price: ₹ 52,348.175
Antigen
Phospho-FAK (Tyr925)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PTK2
Gene Alias
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
14083, 5747
Content And Storage
-20°C
Form
Liquid
Applications
Immunoprecipitation, Western Blot
Concentration
45 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
P34152, Q05397
Gene Symbols
PTK2
Immunogen
Synthetic phosphopeptide corresponding to residues surrounding pTyr925 of human FAK
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- It is not recommended to aliquot this antibody
- Focal Adhesion Kinase (FAK) is a 125 kDa non-receptor protein tyrosine kinase that acts as a substrate for Src and is a key element of integrin signaling
- FAK plays an important role in cell spreading, differentiation, migration, cell death, and acceleration of the G1 to S phase transition of the cell cycle
- FAK has a central catalytic domain and a C-terminal tail that localizes it to focal adhesions, which are sites where cells attach to the extracellular matrix via surface integrin receptors
- Increased FAK tyrosine phosphorylation occurs upon integrin engagement with fibronectin
- Adhesion of murine NIH3T3 fibroblasts to fibronectin promotes association of the Grb2 adapter protein and c-Src PTK with FAK in vivo, and also results in activation of the ERK2 MAP kinase
- In v-Src-transformed NIH3T3, the association of v-Src, Grb2, and Sos with FAK is independent of cell adhesion to fibronectin
- In vitro the Grb2 SH2 domain binds directly to tyrosine-phosphorylated FAK, and the binding site has been identified as Tyr925 by site directed mutagenesis
- Several transcript variants encoding different isoforms have been found for the FAK gene, but the full-length natures of only three of them have been determined.
Compare Similar Items
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Antigen: Phospho-FAK (Tyr925)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PTK2
Gene Alias: CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14083, 5747
Content And Storage: -20°C
Form: Liquid
Applications: Immunoprecipitation, Western Blot
Concentration: 45 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P34152, Q05397
Gene Symbols: PTK2
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pTyr925 of human FAK
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-FAK (Tyr925)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PTK2
Gene Alias:
CG10023; CG10023-PA; CG10023-PB; CG10023-PC; CG10023-PD; CG10023-PF; CG10023-PG; CT28129; DFAK; DFak56; Dmel\CG10023; Dmel_CG10023; DmFAK; EC 2.7.10.2; Fadk; FADK 1; Fak; Fak1; Fak56; fak56D; FAK65D; Fak-PA; Fak-PB; Fak-PC; Fak-PD; Fak-PF; Fak-PG; FAK-related non-kinase polypeptide; focal adhesion kinase; Focal adhesion kinase 1; focal adhesion kinase homolog; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase pp125FAK; focal adhesion kinase-related nonkinase; focal ashension kinase 1; FRNK; I79_019430; Kiaa4203; mKIAA4203; p125FAK; p41/p43FRNK; pFAK; pp125 PTK2; pp125FAK; PPP1R71; Protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; protein tyrosine kinase 2 L homeolog; protein-tyrosine kinase; protein-tyrosine kinase 2; PTK2; PTK2 protein tyrosine kinase 2; ptk2.L; tyrosine kinase; XELAEV_18032408mg; XPFAK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14083, 5747
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunoprecipitation, Western Blot
Concentration:
45 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P34152, Q05397
Gene Symbols:
PTK2
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr925 of human FAK
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Nicastrin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NCSTN
Gene Alias: 9430068N19Rik; AA727311; anterior pharynx-defective 2; Aph2; ATAG1874; D1Dau13e; Kiaa0253; mKIAA0253; NCSTN; Nct; Nicastrin; OTTHUMP00000031840; UNQ1874/PRO4317
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 23385, 289231, 59287
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 183 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P57716, Q8CGU6, Q92542
Gene Symbols: NCSTN
Immunogen: Synthetic peptide corresponding to the carboxy-terminus of human Nicastrin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Nicastrin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NCSTN
Gene Alias:
9430068N19Rik; AA727311; anterior pharynx-defective 2; Aph2; ATAG1874; D1Dau13e; Kiaa0253; mKIAA0253; NCSTN; Nct; Nicastrin; OTTHUMP00000031840; UNQ1874/PRO4317
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
23385, 289231, 59287
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
183 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P57716, Q8CGU6, Q92542
Gene Symbols:
NCSTN
Immunogen:
Synthetic peptide corresponding to the carboxy-terminus of human Nicastrin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: eIF4B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Eif4b
Gene Alias: 2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1975, 300253, 75705
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P23588, Q8BGD9
Gene Symbols: Eif4b
Immunogen: Synthetic peptide corresponding to residues at the amino terminus of human eIF4B
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
eIF4B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Eif4b
Gene Alias:
2310046H11Rik; AL024095; C85189; Eif4a2; EIF4B; eIF-4B; Eukaryotic translation initiation factor 4B; hCG_2014609; hypothetical protein; PRO1843
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1975, 300253, 75705
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P23588, Q8BGD9
Gene Symbols:
Eif4b
Immunogen:
Synthetic peptide corresponding to residues at the amino terminus of human eIF4B
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-CrkL (Tyr207)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CRKL
Gene Alias: 1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12929, 1399, 287942
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P46109, P47941, Q5U2U2
Gene Symbols: CRKL
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pTyr207 of human CrkL
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-CrkL (Tyr207)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CRKL
Gene Alias:
1110025F07Rik; AA589403; AI325100; CRK like proto-oncogene, adaptor protein; CRKL; crkl {ECO:0000312; crk-like protein; crk-like protein {ECO:0000250; Crkol; EMBL:AAH85865.1, ECO:0000312; OTTHUMP00000198539; RGD:1308531}; UniProtKB:P46109}; v-crk avian sarcoma virus CT10 oncogene homolog-like; v-crk sarcoma virus CT10 oncogene homolog (avian)-like; v-crk sarcoma virus CT10 oncogene homolog-like
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12929, 1399, 287942
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P46109, P47941, Q5U2U2
Gene Symbols:
CRKL
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pTyr207 of human CrkL
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Non-human Primate, Rat
Product Type:
Antibody
Isotype:
IgG