PIPA586451

AIF Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586451-Each-of-1 In Stock ₹ 44,705.10

PIPA586451 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

AIF

Classification

Polyclonal

Conjugate

Unconjugated

Gene

AIFM1

Gene Alias

AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26926, 83533, 9131

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O95831, Q9JM53, Q9Z0X1

Gene Symbols

AIFM1

Immunogen

Synthetic peptide, corresponding to amino acids 61-110 of Human AIF-M1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Apoptosis Inducing Factor (AIF) causes chromatin condensation and DNA fragmentation
  • AIF was recently identified, and cloned
  • Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation
  • These changes are triggered by the activation of members of caspase family, caspase activated DNase, and several novel proteins
  • Like the critical molecules, cytochrome c and caspase-9, in apoptosis, AIF localizes in mitochondria
  • AIF translocates to the nucleus when apoptosis is induced and induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9
  • AIF induces chromatin condensation and large scale DNA fragmentation, which are the hallmarks of apoptosis, of the isolated nucleus and the nucleus in live cells by microinjection and apoptosis stimuli
  • AIF is highly conserved between human and mouse and widely expressed
  • Mutations in the AIF gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy
  • Alternative splicing results in multiple transcript variants of AIF and a related pseudogene has been identified on chromosome 10.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586451

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Antigen:
AIF

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AIFM1

Gene Alias:
AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26926, 83533, 9131

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O95831, Q9JM53, Q9Z0X1

Gene Symbols:
AIFM1

Immunogen:
Synthetic peptide, corresponding to amino acids 61-110 of Human AIF-M1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586452

--


Antigen:
Apolipoprotein J

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Clu

Gene Alias:
AAG4, Aging associated protein 4, Aging-associated gene 4 protein, aging-associated protein 4, AI893575, apo j, Apo J a, Apo J alpha, Apo J b, Apo J beta, Apo J a, Apo J β, Apo Ja, Apo Jb, ApoJ, Apo-J, ApoJ a, ApoJ alpha, ApoJ b, ApoJ beta, ApoJ a, ApoJ β, ApoJa, ApoJalpha, ApoJb, ApoJbeta, Apolipoprotein J, CLI, Clu, CLU1, CLU2, clusterin, Clusterin alpha / beta chain, Clusterin alpha chain, Clusterin beta chain, Clustrin, Complement associated protein SP40, complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Complement cytolysis inhibitor b chain, complement lysis inhibitor, complement-associated protein SP-40,40, D14Ucla3, DAG, Dimeric acid glycoprotein, GP80, HGNC:2095, ku70-binding protein 1, Ku70-binding protein 1 (KUB1), KUB1, MGC24903, Msgp-2, NA1/NA2, RATTRPM2B, SGP2, Sgp-2, SP40, SP-40, Sugp-2, sulfated glycoprotein 2, Sulfated glycoprotein 2 (SGP2), testosterone repressed prostate message, testosterone repressed prostate message 2, Testosterone repressed prostate message 2 (TPRM2B), testosterone repressed prostate message-2, testosterone-repressed prostate message, testosterone-repressed prostate message 2, testostrone-repressed prostate message 2, Trpm2, TRPM-2, TRPM2B, Trpmb

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1191, 12759, 24854

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P05371, P10909, Q06890

Gene Symbols:
Clu

Immunogen:
Synthetic peptide, corresponding to amino acids C-terminus of Human Clusterin-alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586455

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Antigen:
MLH1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Mlh1

Gene Alias:
1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4292

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P40692

Gene Symbols:
Mlh1

Immunogen:
Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586456

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Antigen:
MSH6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MSH6

Gene Alias:
AU044881, AW550279, cb326, DNA mismatch repair protein Msh6, g/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, LOC100360342, mismatch repair protein Msh6, Msh6, mutS (E. coli) homolog 6, MutS alpha 160kDa subunit, mutS homolog 6, mutS homolog 6 (E. coli), MutS protein homolog 6, MutS-alpha 160 kDa subunit, MutS-alpha 160kDa subunit, p160, rCG61559-like, Sperm associated protein, sperm-associated protein, wu:fb36c12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17688, 2956

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P52701, P54276

Gene Symbols:
MSH6

Immunogen:
Synthetic peptide, corresponding to amino acids 350-400 of Human MSH6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG