PIPA586942
Phospho-ATM (Ser1981) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586942-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA586942 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
Phospho-ATM (Ser1981)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11920, 300711, 472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
Q13315, Q62388
Gene Symbols
ATM
Immunogen
A synthetic peptide corresponding to residues in Human ATM around the phosphorylation site of ser1981.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This polyclonal antibody detects endogenous levels of ATM protein only when phosphorylated at Ser1981
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: Phospho-ATM (Ser1981)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11920, 300711, 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q13315, Q62388
Gene Symbols: ATM
Immunogen: A synthetic peptide corresponding to residues in Human ATM around the phosphorylation site of ser1981.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-ATM (Ser1981)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11920, 300711, 472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q13315, Q62388
Gene Symbols:
ATM
Immunogen:
A synthetic peptide corresponding to residues in Human ATM around the phosphorylation site of ser1981.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ROCK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ROCK2
Gene Alias: B230113H15Rik, KIAA0619, mKIAA0619, p150 ROK-alpha, p164 ROCK-2, Rho associated coiled-coil containing protein kinase 2, Rho kinase 2, RhoA - binding serine/threosine kinase alpha (ROK - alpha), rhoA-binding kinase 2, Rho-associated coiled-coil containing protein kinase 2, Rho-associated coiled-coil forming kinage 2, Rho-associated coiled-coil forming kinase 2, rho-associated protein kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, rho-associated, coiled-coil-containing protein kinase II, Rho-kinase, ROCK II, Rock2, Rock2m, rockii, ROCK-II, ROK, ROKalpha
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19878, 25537, 9475
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: O75116, P70336, Q62868
Gene Symbols: ROCK2
Immunogen: Recombinant full length Human Rock2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ROCK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ROCK2
Gene Alias:
B230113H15Rik, KIAA0619, mKIAA0619, p150 ROK-alpha, p164 ROCK-2, Rho associated coiled-coil containing protein kinase 2, Rho kinase 2, RhoA - binding serine/threosine kinase alpha (ROK - alpha), rhoA-binding kinase 2, Rho-associated coiled-coil containing protein kinase 2, Rho-associated coiled-coil forming kinage 2, Rho-associated coiled-coil forming kinase 2, rho-associated protein kinase 2, Rho-associated, coiled-coil-containing protein kinase 2, rho-associated, coiled-coil-containing protein kinase II, Rho-kinase, ROCK II, Rock2, Rock2m, rockii, ROCK-II, ROK, ROKalpha
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19878, 25537, 9475
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
O75116, P70336, Q62868
Gene Symbols:
ROCK2
Immunogen:
Recombinant full length Human Rock2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: RelB
Classification: Polyclonal
Conjugate: Unconjugated
Gene: RELB
Gene Alias: avian reticuloendotheliosis viral (v-rel) oncogene related B, IREL, I-REL, OTTHUMP00000221313, rel b, RELB, REL-B, RELB proto-oncogene, NF-kB subunit, shep, transcription factor RelB, v-rel avian reticuloendotheliosis viral oncogene homolog B, v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), v-rel reticuloen, v-rel reticuloendotheliosis viral oncogene homolog B, v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 19698, 5971
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q01201, Q04863
Gene Symbols: RELB
Immunogen: Synthetic peptide, corresponding to amino acids 530-580 of Human Rel B.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
RelB
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
RELB
Gene Alias:
avian reticuloendotheliosis viral (v-rel) oncogene related B, IREL, I-REL, OTTHUMP00000221313, rel b, RELB, REL-B, RELB proto-oncogene, NF-kB subunit, shep, transcription factor RelB, v-rel avian reticuloendotheliosis viral oncogene homolog B, v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3), v-rel reticuloen, v-rel reticuloendotheliosis viral oncogene homolog B, v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
19698, 5971
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q01201, Q04863
Gene Symbols:
RELB
Immunogen:
Synthetic peptide, corresponding to amino acids 530-580 of Human Rel B.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Filamin B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: FLNB
Gene Alias: ABP-278, ABP-280, ABP-280 homolog, ABP-280-like protein, actin binding protein 278, actin-binding-like protein, AL024016, AOI, beta-filamin, Fh1, filamin B, filamin B, beta, filamin homolog 1, filamin, beta, filamin-3, FilaminB, Filamin-B, FLN1L, FLN3, FLNB, FLN-B, Larsen syndrome 1 (autosomal dominant), LRS1, SCT, TABP, TAP, thyroid autoantigen, Truncated ABP, Truncated actin-binding protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 2317, 286940, 306204
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O75369, Q80X90
Gene Symbols: FLNB
Immunogen: Recombinant protein of human FLNB.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Filamin B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
FLNB
Gene Alias:
ABP-278, ABP-280, ABP-280 homolog, ABP-280-like protein, actin binding protein 278, actin-binding-like protein, AL024016, AOI, beta-filamin, Fh1, filamin B, filamin B, beta, filamin homolog 1, filamin, beta, filamin-3, FilaminB, Filamin-B, FLN1L, FLN3, FLNB, FLN-B, Larsen syndrome 1 (autosomal dominant), LRS1, SCT, TABP, TAP, thyroid autoantigen, Truncated ABP, Truncated actin-binding protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
2317, 286940, 306204
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O75369, Q80X90
Gene Symbols:
FLNB
Immunogen:
Recombinant protein of human FLNB.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG