PIPA586677
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586677-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586677 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
Synthetic peptide, corresponding to amino acids 1957-2006 of Human ATM.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
Compare Similar Items
Show Difference
Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: Synthetic peptide, corresponding to amino acids 1957-2006 of Human ATM.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
Synthetic peptide, corresponding to amino acids 1957-2006 of Human ATM.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CaMKII alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CAMK2A
Gene Alias: alpha CaM kinase II, alpha-CaMKII, Ca2+/calmodulin-dependent protein kinase II, Ca2+/calmodulin-dependent protein kinase II alpha, Calci, calcium/calmodulin dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase II alpha subunit, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain, calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II alpha subunit, caM kinase II subunit alpha, CaMK II, CAMK2, Camk2a, CAMKA, CaMKII, CaMK-II alpha subunit, caMK-II subunit alpha, CaMKIINalpha, CaM-kinase II alpha chain, EC 2.7.11.17, KIAA0968, mKIAA0968, OTTHUMP00000165787, OTTHUMP00000165788, Phospho-CaMKI, PK2CDD, PKCCD, R74975
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12322, 25400, 815
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P11275, P11798, Q9UQM7
Gene Symbols: CAMK2A
Immunogen: Synthetic peptide, corresponding to amino acids 260-310 of Human CaMKIIalpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CaMKII alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CAMK2A
Gene Alias:
alpha CaM kinase II, alpha-CaMKII, Ca2+/calmodulin-dependent protein kinase II, Ca2+/calmodulin-dependent protein kinase II alpha, Calci, calcium/calmodulin dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase (CaM kinase) II alpha, calcium/calmodulin-dependent protein kinase II alpha, calcium/calmodulin-dependent protein kinase II alpha subunit, calcium/calmodulin-dependent protein kinase II alpha-B subunit, calcium/calmodulin-dependent protein kinase type II alpha chain, calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II alpha subunit, caM kinase II subunit alpha, CaMK II, CAMK2, Camk2a, CAMKA, CaMKII, CaMK-II alpha subunit, caMK-II subunit alpha, CaMKIINalpha, CaM-kinase II alpha chain, EC 2.7.11.17, KIAA0968, mKIAA0968, OTTHUMP00000165787, OTTHUMP00000165788, Phospho-CaMKI, PK2CDD, PKCCD, R74975
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12322, 25400, 815
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P11275, P11798, Q9UQM7
Gene Symbols:
CAMK2A
Immunogen:
Synthetic peptide, corresponding to amino acids 260-310 of Human CaMKIIalpha.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Histone H2A.X
Classification: Polyclonal
Conjugate: Unconjugated
Gene: H2AX
Gene Alias: AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 15270, 3014, 500987
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P16104, P27661
Gene Symbols: H2AX
Immunogen: Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Histone H2A.X
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
H2AX
Gene Alias:
AW228881, gamma H2AX, gammaH2ax, H2A histone family member X, H2A histone family, member X, H2A.X, H2A.X variant histone, H2A/X, h2afx, H2ax, H2AX histone, Hist5-2ax, histone 5 protein 2ax, histone H2A.x, Histone H2a/x, Histone H2AX, RGD1566119, similar to H2A histone family, member X, zgc:56329
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
15270, 3014, 500987
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P16104, P27661
Gene Symbols:
H2AX
Immunogen:
Synthetic peptide, corresponding to amino acids 120-170 of Human Histone H2A.X.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AMPK alpha-1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Prkaa1
Gene Alias: 5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 105787, 5562, 65248
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P54645, Q13131, Q5EG47
Gene Symbols: Prkaa1
Immunogen: Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AMPK alpha-1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Prkaa1
Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
105787, 5562, 65248
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P54645, Q13131, Q5EG47
Gene Symbols:
Prkaa1
Immunogen:
Synthetic peptide, corresponding to amino acids 470-520 of Human AMPKalpha1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG