PIPA587453
NEDD4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587453-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587453 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
NEDD4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NEDD4
Gene Alias
AA959633, AL023035, AU019897, cell proliferation-inducing gene 53 protein, E3 ubiquitin-protein ligase NEDD4, E430025J12Rik, HECT-type E3 ubiquitin transferase NEDD4, Kiaa0093, mKIAA0093, NEDD4, NEDD-4, NEDD4 E3 ubiquitin protein ligase, Nedd4-1, Nedd4a, Neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated 4, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, neural precursor cell expressed, developmentally down-regulated gene 4, neural precursor cell expressed, developmentally down-regulated gene 4a, neural precursor cell expressed, developmentally down-regulted gene 4, OTTHUMP00000217840, OTTHUMP00000217841, OTTHUMP00000217842, PIG53, receptor-potentiating factor 1, RPF1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4734
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
2.5 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P46934
Gene Symbols
NEDD4
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4 (NP_9406822)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: GSYSSNGSDF GSCASITSGG SYTNSVISDS SSYTFPPSDD TFLGGNLPSD STSNRSVPNR NTTPCEIFSR STSTDPFVQD DLEHGLEIMK LPVSRNTKIP LKRYSSLVIF PRSPSTTRPT SPTSLCTLLS KGSYQTSHQF IISPSEIAHN EDGTSAKGFL STAVNGLRLS KTICTPGEVR DIRPLHRKGS LQKKIVLSNN TPRQTVCEKS SEGYSCVSVH FTQRKAATLD CETTNGDCKP EMSEIKLNSD SEYIKLMHRT SACLPSSQNV DCQININGEL ERPHSQMNKN HGILRRSISL G; Positive Samples: U-251MG, HeLa, Jurkat, A-549, SKOV3; Cellular Location: Cell membrane, Cytoplasm, Peripheral membrane protein The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
- It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
- It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
- It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
- It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
- NEDD4 protein is localized to the sarcolemmal region of muscle fibers
- Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
- Hence it acts as down regulator of Notch-1 gene expression.
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Show Difference
Antigen: NEDD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEDD4
Gene Alias: AA959633, AL023035, AU019897, cell proliferation-inducing gene 53 protein, E3 ubiquitin-protein ligase NEDD4, E430025J12Rik, HECT-type E3 ubiquitin transferase NEDD4, Kiaa0093, mKIAA0093, NEDD4, NEDD-4, NEDD4 E3 ubiquitin protein ligase, Nedd4-1, Nedd4a, Neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated 4, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, neural precursor cell expressed, developmentally down-regulated gene 4, neural precursor cell expressed, developmentally down-regulated gene 4a, neural precursor cell expressed, developmentally down-regulted gene 4, OTTHUMP00000217840, OTTHUMP00000217841, OTTHUMP00000217842, PIG53, receptor-potentiating factor 1, RPF1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4734
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.5 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P46934
Gene Symbols: NEDD4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4 (NP_9406822)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
NEDD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEDD4
Gene Alias:
AA959633, AL023035, AU019897, cell proliferation-inducing gene 53 protein, E3 ubiquitin-protein ligase NEDD4, E430025J12Rik, HECT-type E3 ubiquitin transferase NEDD4, Kiaa0093, mKIAA0093, NEDD4, NEDD-4, NEDD4 E3 ubiquitin protein ligase, Nedd4-1, Nedd4a, Neural precursor cell expressed developmentally down-regulated protein 4, neural precursor cell expressed, developmentally down-regulated 4, neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase, neural precursor cell expressed, developmentally down-regulated gene 4, neural precursor cell expressed, developmentally down-regulated gene 4a, neural precursor cell expressed, developmentally down-regulted gene 4, OTTHUMP00000217840, OTTHUMP00000217841, OTTHUMP00000217842, PIG53, receptor-potentiating factor 1, RPF1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4734
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.5 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P46934
Gene Symbols:
NEDD4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-460 of human NEDD4 (NP_9406822)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PKN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PKN1
Gene Alias: DBK, F730027O18Rik, PAK1, PAK-1, PKN, PKN1, PKN-ALPHA, PRK1, Prkcl1, Protease-activated kinase 1, protein kinase C-like 1, Protein kinase C-like PKN, protein kinase C-related kinase 1, protein kinase N1, protein kinase PKN, protein kinase PKN-alpha, Protein-kinase C-related kinase 1, serine/threonine kinase 3, serine/threonine protein kinase N, serine/threonine-protein kinase N1, serine-threonine kinase N, serine-threonine protein kinase N, Stk3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 320795, 5585
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.53 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P70268, Q16512
Gene Symbols: PKN1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_0027323)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PKN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PKN1
Gene Alias:
DBK, F730027O18Rik, PAK1, PAK-1, PKN, PKN1, PKN-ALPHA, PRK1, Prkcl1, Protease-activated kinase 1, protein kinase C-like 1, Protein kinase C-like PKN, protein kinase C-related kinase 1, protein kinase N1, protein kinase PKN, protein kinase PKN-alpha, Protein-kinase C-related kinase 1, serine/threonine kinase 3, serine/threonine protein kinase N, serine/threonine-protein kinase N1, serine-threonine kinase N, serine-threonine protein kinase N, Stk3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
320795, 5585
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.53 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P70268, Q16512
Gene Symbols:
PKN1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human PKN1 (NP_0027323)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: NOTCH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOTCH2
Gene Alias: AGS2, AI853703, HJCYS, hN2, Motch B, N2, N2ECD, N2ICD, Neurogenic locus notch homolog protein 2, notch 2, Notch 2 extracellular truncation, Notch 2 intracellular domain, notch gene homolog 2, Notch homolog 2, notch receptor 2, Notch2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18129, 4853
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.16 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O35516, Q04721
Gene Symbols: NOTCH2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 2242-2471 of human NOTCH2 (NP_0777192)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NOTCH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOTCH2
Gene Alias:
AGS2, AI853703, HJCYS, hN2, Motch B, N2, N2ECD, N2ICD, Neurogenic locus notch homolog protein 2, notch 2, Notch 2 extracellular truncation, Notch 2 intracellular domain, notch gene homolog 2, Notch homolog 2, notch receptor 2, Notch2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18129, 4853
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.16 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O35516, Q04721
Gene Symbols:
NOTCH2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2242-2471 of human NOTCH2 (NP_0777192)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: eIF3a
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF3A
Gene Alias: 150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13669, 8661
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 0.68 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P23116, Q14152
Gene Symbols: EIF3A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
eIF3a
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF3A
Gene Alias:
150/170, A830012B05Rik, Centrosomin, centrosomin homolog, Csma, cytoplasmic protein p167, Eif3, eIF3 p167, eIF3 p180, eIF3 p185, EIF3, p180 subunit, eIF3a, eIF3a {ECO:0000255, eIF3-p170, EIF3S10, eIF-3-theta, eIF3-theta, eIF-3-theta {ECO:0000255, eukaryotic translation initiation factor 3 subunit 10, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT 10 (EIF-3 THETA) (EIF3 P167) (EIF3 P180) (EIF3 P185) (P162 PROTEIN) (CENTROSOMIN), eukaryotic translation initiation factor 3 subunit 10 {ECO:0000255, eukaryotic translation initiation factor 3 subunit A, eukaryotic translation initiation factor 3 subunit A {ECO:0000255, eukaryotic translation initiation factor 3, subunit 10 (theta), eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD), eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD), eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa, eukaryotic translation initiation factor 3, subunit 10, 170kD, eukaryotic translation initi
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13669, 8661
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
0.68 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P23116, Q14152
Gene Symbols:
EIF3A
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human EIF3A (NP_0037411)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG