KLRB1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA593293-Each-of-1 | In Stock | ₹ 45,047.34 |
PIPA593293 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,047.34
GST (18%): ₹ 8,108.521
Total Price: ₹ 53,155.861
Antigen
KLRB1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Klrb1
Gene Alias
4930431A04Rik, Antigen 3.2.3, CD161, CD161 antigen-like family member A, CD161 antigen-like family member B, CD161a, CD161b, CLEC5B, C-type lectin domain family 5 member B, EMBL:AAQ11375.1}, Gm4696, HNKR-P1a, Immunoreceptor NKR-P1E, immunoreceptor NKR-P1G, inhibitory receptor NKR-P1B, killer cell lectin like receptor B1, killer cell lectin-like receptor subfamily A member 1 complex, killer cell lectin-like receptor subfamily B member 1, killer cell lectin-like receptor subfamily B member 1 complex, killer cell lectin-like receptor subfamily B member 1A, killer cell lectin-like receptor subfamily B member 1B, killer cell lectin-like receptor subfamily B member 1B allele A, Killer cell lectin-like receptor subfamily B member 1B allele B, killer cell lectin-like receptor subfamily B member 1B allele C, killer cell lectin-like receptor subfamily B member 1D, killer cell lectin-like receptor subfamily B member 1F, killer cell lectin-like receptor subfamily B member 1G, killer cell lectin-like receptor subfamily B, member 1, killer cell lectin-like receptor subfamily B, member 1A, Klrb1, Klrb1a, Klrb1b, klrb1b {ECO:0000312, Klrb1d, Klrb1f, Klrb1g, Klrb6, lectin-like transmembrane protein Nkrp1g, Ly55, Ly-55, Ly55a, ly-55A, Ly55b, ly-55b, Ly55d, ly-55d, lymphocyte antigen 55, lymphocyte antigen 55 complex, locus A, lymphocyte antigen 55 complex, locus B, lymphocyte antigen 55 complex, locus D, lymphocyte antigen 55A, lymphocyte antigen 55b, lymphocyte antigen 55d, MGC138614, natural killer cell receptor, natural killer cell receptor protein NKR-P1A, natural killer cell receptor protein NKR-P1B, natural killer cell receptor-P1, natural killer cell surface protein NKR-P1B allele B6, Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344, natural killer cell surface protein NKR-P1B allele SJL/BALB, natural killer cell surface protein NKR-P1B allele TO, natural killer cell surface protein NKR-P1G, Natural killer cell surface protein P1-2, natural killer cell surface protein P1-3.2.3, Natural killer cell surface protein P1A, natural killer lectin-like receptor 1E, natural killer lectin-like receptor protein 1 e, NKR, NKR-P1, NKR-P1 2, NKR-P1 3.2.3, NKR-P1 34, NKR-P1.7, NKRP12, NKRP1A, NKR-P1A, Nkrp1-a, Nkrp1b, Nkr-p1b, Nkrp1-b, Nkrp1d, NKR-P1D, Nkrp1e, Nkr-p1e, Nkrp-1e, Nkrp1g, NKR-P1G, RGD:2975}
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100043861, 17057, 25192, 362443, 3820, 689817, 80782
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.65 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
A4KWA1, P27471, P27811, P27812, Q0ZUP0, Q0ZUP1, Q12918
Gene Symbols
Klrb1, Klrb1a, Klrb1b
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 73-140 of human KLRB1 (NP_0022491)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: KCSVDIQQSR NKTTERPGLL NCPIYWQQLR EKCLLFSHTV NPWNNSLADC STKESSLLLI RDKDELIH; Positive Samples: Rat liver, HT-29, Mouse liver; Cellular Location: Membrane, Single-pass type II membrane protein KLRB1 (Killer cell lectin like receptor subfamily B, member 1, CD-161) protein is classified as a type II membrane protein because it has an external C terminus
- KLRB1 cell surface antigen is expressed by almost all NK cells and in a small subset of CD3+ve T cells
- KLRB1 is a homodimeric cell surface protein, comprising two chains with molecular weights ranging from 40-44kDa
- KLRB1 plays an inhibitory role on natural killer (NK) cells
- Activation of KLRB1 leads to acid sphingomyelnase/SMPD1 stimulation and an increase in intracellular ceramide
- Moreover, there is also an activation of AKT1/PKB and RPS6KA1/RSK1 kinase stimulation, and T cell proliferation by anti-CD3
- KLRB1 acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope and to the N-acetyllactosamine epitope
- KLRB1 also binds to CLEC2D/LLT1 as a ligand, and inhibits NK cell-mediated cytotoxicity as well as interferon-gamma secretion in target cells
- The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain.
Compare Similar Items
Show Difference
Antigen: KLRB1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Klrb1
Gene Alias: 4930431A04Rik, Antigen 3.2.3, CD161, CD161 antigen-like family member A, CD161 antigen-like family member B, CD161a, CD161b, CLEC5B, C-type lectin domain family 5 member B, EMBL:AAQ11375.1}, Gm4696, HNKR-P1a, Immunoreceptor NKR-P1E, immunoreceptor NKR-P1G, inhibitory receptor NKR-P1B, killer cell lectin like receptor B1, killer cell lectin-like receptor subfamily A member 1 complex, killer cell lectin-like receptor subfamily B member 1, killer cell lectin-like receptor subfamily B member 1 complex, killer cell lectin-like receptor subfamily B member 1A, killer cell lectin-like receptor subfamily B member 1B, killer cell lectin-like receptor subfamily B member 1B allele A, Killer cell lectin-like receptor subfamily B member 1B allele B, killer cell lectin-like receptor subfamily B member 1B allele C, killer cell lectin-like receptor subfamily B member 1D, killer cell lectin-like receptor subfamily B member 1F, killer cell lectin-like receptor subfamily B member 1G, killer cell lectin-like receptor subfamily B, member 1, killer cell lectin-like receptor subfamily B, member 1A, Klrb1, Klrb1a, Klrb1b, klrb1b {ECO:0000312, Klrb1d, Klrb1f, Klrb1g, Klrb6, lectin-like transmembrane protein Nkrp1g, Ly55, Ly-55, Ly55a, ly-55A, Ly55b, ly-55b, Ly55d, ly-55d, lymphocyte antigen 55, lymphocyte antigen 55 complex, locus A, lymphocyte antigen 55 complex, locus B, lymphocyte antigen 55 complex, locus D, lymphocyte antigen 55A, lymphocyte antigen 55b, lymphocyte antigen 55d, MGC138614, natural killer cell receptor, natural killer cell receptor protein NKR-P1A, natural killer cell receptor protein NKR-P1B, natural killer cell receptor-P1, natural killer cell surface protein NKR-P1B allele B6, Natural killer cell surface protein NKR-P1B allele RNK/SD/BN/F344, natural killer cell surface protein NKR-P1B allele SJL/BALB, natural killer cell surface protein NKR-P1B allele TO, natural killer cell surface protein NKR-P1G, Natural killer cell surface protein P1-2, natural killer cell surface protein P1-3.2.3, Natural killer cell surface protein P1A, natural killer lectin-like receptor 1E, natural killer lectin-like receptor protein 1 e, NKR, NKR-P1, NKR-P1 2, NKR-P1 3.2.3, NKR-P1 34, NKR-P1.7, NKRP12, NKRP1A, NKR-P1A, Nkrp1-a, Nkrp1b, Nkr-p1b, Nkrp1-b, Nkrp1d, NKR-P1D, Nkrp1e, Nkr-p1e, Nkrp-1e, Nkrp1g, NKR-P1G, RGD:2975}
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100043861, 17057, 25192, 362443, 3820, 689817, 80782
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.65 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: A4KWA1, P27471, P27811, P27812, Q0ZUP0, Q0ZUP1, Q12918
Gene Symbols: Klrb1, Klrb1a, Klrb1b
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 73-140 of human KLRB1 (NP_0022491)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: MYO1C
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MYO1C
Gene Alias: C80397, FLJ23903, mm1beta, MMIb, MMI-beta, myo1c, myo1ca, MYO1E, myosin 1c, paralog a, myosin heavy chain myr 2, myosin I, Myosin I beta, myosin IB, myosin IC, myosin Ic, paralog a, myosin IC-like, myosin-I beta, myosin-Ibeta, myosin-Ic, Myr2, NMI, nuclear myosin I, nuclear myosin I beta, si:ch211-69i14.4, unconventional myosin Myr2 I heavy chain, unconventional myosin-Ic
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17913, 4641, 65261
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.95 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O00159, Q63355, Q9WTI7
Gene Symbols: MYO1C
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 769-1028 of human MYO1C (NP_2036933)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: NASP
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NASP
Gene Alias: 5033430J04Rik, AI131596, AI317140, D4Ertd767e, DKFZp547F162, EMBL:AAH81913.1}, Epcs32, FLB7527, FLJ31599, FLJ35510, histone H1-binding protein, HMDRA1, MGC19722, MGC20372, MGC2297, Nasp, nasp {ECO:0000312, NASP histone chaperone, nasp protein, Nasp-T, Nuclear autoantigenic sperm protein, nuclear autoantigenic sperm protein (histone-binding), PRO1999, somatic histone binding protein NASP, wu:fd20g12, zgc:56007, zgc:85651
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 298441, 4678, 50927
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.22 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P49321, Q66HD3, Q99MD9
Gene Symbols: NASP
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-449 of human NASP (NP_6895112)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
