PIPA595370

TAK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595370-Each-of-1 In Stock ₹ 44,705.10

PIPA595370 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TAK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP3K7

Gene Alias

B430101B05, C87327, hypothetical protein LOC553788, I79_000697, M3K7, map3k7, map3k7.L, MAPKKK, MEKK7, mitogen activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7 L homeolog, RP1-154G14.1, si:ch211-225h9.1, Tak1, TAK1z, TGF1a, TGF-beta activated kinase 1, TGF-beta-activated kinase 1, TGF-beta-activated kinase TAK1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1, XELAEV_18027270mg, xTAK1, zgc:110612

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

26409, 313121, 6885

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

O43318, P0C8E4, Q62073

Gene Symbols

MAP3K7

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
  • Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
  • It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
  • Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
  • TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
  • Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
  • In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
  • Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595370

--


Antigen:
TAK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K7

Gene Alias:
B430101B05, C87327, hypothetical protein LOC553788, I79_000697, M3K7, map3k7, map3k7.L, MAPKKK, MEKK7, mitogen activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7, mitogen-activated protein kinase kinase kinase 7 L homeolog, RP1-154G14.1, si:ch211-225h9.1, Tak1, TAK1z, TGF1a, TGF-beta activated kinase 1, TGF-beta-activated kinase 1, TGF-beta-activated kinase TAK1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1, XELAEV_18027270mg, xTAK1, zgc:110612

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26409, 313121, 6885

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 4MG trehalose and no preservative

Gene Accession No.:
O43318, P0C8E4, Q62073

Gene Symbols:
MAP3K7

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human TAK1 (566-603aa RLVQEHKKLLDENKSLSTYYQQCKKQLEVIRSQQQKRQ).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595371

--


Antigen:
TPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116596, 1326

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P41279, Q63562

Gene Symbols:
MAP3K8

Immunogen:
E.coli-derived human MAP3K8 recombinant protein (Position: D9-L193).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595372

--


Antigen:
CD273 (B7-DC)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PDCD1LG2

Gene Alias:
B7 dendritic cell molecule, B7DC, B7-DC, bA574F11.2, Btdc, Butyrophilin B7-DC, butyrophilin-like protein, CD273, F730015O22Rik, MGC124039, MGC124040, PD1 ligand 2, PD-1 ligand 2, PD-1-ligand 2, PDCD1 ligand 2, PDCD1L2, Pdcd1lg2, Pdl2, PD-L2, Programmed cell death 1 ligand 2, programmed death ligand 2

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
80380

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q9BQ51

Gene Symbols:
PDCD1LG2

Immunogen:
E.coli-derived human B7 DC recombinant protein (Position: L20-T220).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595373

--


Antigen:
VAMP7

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Vamp7

Gene Alias:
Sybl1, synaptobrevin-like 1, synaptobrevin-like protein 1, tetanus neurotoxin-insensitive VAMP, tetanus-insensitive VAMP, TIVAMP, Ti-VAMP, vamp, Vamp7, VAMP-7, vesicle associated membrane protein 7, vesicle-associated membrane protein 7

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
6845, 85491

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P51809, Q9JHW5

Gene Symbols:
Vamp7

Immunogen:
E.coli-derived human SYBL1 recombinant protein (Position: N24-T190).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG