PIPA595918

E6AP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595918-Each-of-1 In Stock ₹ 44,705.10

PIPA595918 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

E6AP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UBE3A

Gene Alias

4732496B02, 5830462N02Rik, A130086L21Rik, ANCR, AS, CTCL tumor antigen se37-2, E6AP, E6-AP, E6-AP ubiquitin protein ligase, E6AP ubiquitin-protein ligase, EPVE6AP, FLJ26981, HECT-type ubiquitin transferase E3A, HPVE6A, human papilloma virus E6-associated protein, human papillomavirus E6-associated protein, mKIAA4216, oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54, UBE3A, ubiquitin conjugating enzyme E3A, ubiquitin protein ligase E3A, ubiquitin-protein ligase E3A

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

22215, 361585, 7337

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

0.13 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.

O08759, Q05086

Gene Symbols

UBE3A

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human UBE3A (NP_5708531)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: KLIRLWSKYN ADQIRRMMET FQQLITYKVI SNEFNSRNLV NDDDAIVAAS KCLKMVYYAN VVGGEVDTNH NEEDDEEPIP ESSELTLQEL LGEERRNKKG PRVDPLETEL GVKTLDCRKP LIPFEEFINE PLNEVLEMDK DYTFFKVETE NKFSFMTCPF ILNAVTKNLG LYYDNRIRMY SERRITVLYS LVQGQQLNPY LRLKVRRDHI IDDALVRLEM IAMENPADLK KQLYVEFEGE QGVDEGGVSK EFFQLVVEEI FNPDIGMFTY DESTKLFWFN PSSFETEGQF T; Positive Samples: 293T, SKOV3, BT-474, U-251MG, Jurkat, Mouse brain, Mouse heart, Mouse thymus, Rat brain; Cellular Location: Cytoplasm, Nucleus UBE3A (ubiquitin-protein ligase E3A, AKA E6AP) is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates
  • Several substrates have been identified including the ARNTL/BMAL1, ARC, RAD23A, RAD23B, MCM7, annexin A1, the PML tumor suppressor, and the cell cycle regulator CDKN1B
  • Additionally, UBE3A may function as a cellular quality control ubiquitin ligase by helping the degradation of the cytoplasmic misfolded proteins
  • UBE3A also plays an important role in the regulation of the circadian clock
  • Defects in UBE3A are a cause of Angelman syndrome (AS).

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA595918

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Antigen:
E6AP

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
UBE3A

Gene Alias:
4732496B02, 5830462N02Rik, A130086L21Rik, ANCR, AS, CTCL tumor antigen se37-2, E6AP, E6-AP, E6-AP ubiquitin protein ligase, E6AP ubiquitin-protein ligase, EPVE6AP, FLJ26981, HECT-type ubiquitin transferase E3A, HPVE6A, human papilloma virus E6-associated protein, human papillomavirus E6-associated protein, mKIAA4216, oncogenic protein-associated protein E6-AP, Renal carcinoma antigen NY-REN-54, UBE3A, ubiquitin conjugating enzyme E3A, ubiquitin protein ligase E3A, ubiquitin-protein ligase E3A

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22215, 361585, 7337

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.13 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O08759, Q05086

Gene Symbols:
UBE3A

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-590 of human UBE3A (NP_5708531)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595919

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Antigen:
Vinculin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
VCL

Gene Alias:
9430097D22, AA571387, AI462105, AW545629, CMD1W, CMH15, epididymis luminal protein 114, HEL114, metavinculin, meta-vinculin, metavinculin {ECO:0000250, MV, MVCL, RP11-178G16.3, UniProtKB:P18206}, unnamed protein product, Vcl, vcl {ECO:0000250, VIN, vinc, vinc 1, VINC1, Vinculin, vinculin {ECO:0000250

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22330, 305679, 7414

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Western Blot

Concentration:
1.76 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P18206, P85972, Q64727

Gene Symbols:
VCL

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 767-1066 of human Vinculin (NP_0033641)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595920

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Antigen:
CD1d

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CD1D

Gene Alias:
AI747460, Antigen-presenting glycoprotein CD1d, antigen-presenting glycoprotein CD1d1, Cd1, CD1.1, CD1A, Cd1d, CD1D antigen, CD1D antigen, d polypeptide, CD1d molecule, CD1d.1, Cd1d1, CD1d1 antigen, CD1d1 molecule, differentiation antigen CD1-alpha-3, HMC class I antigen-like glycoprotein CD1D, Ly-38, R3, R3G1, T-cell surface glycoprotein CD1d, T-cell surface glycoprotein CD1d1, thymocyte antigen CD1D

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12479, 912

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.16 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P11609, P15813

Gene Symbols:
CD1D, Cd1d1

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-190 of human CD1D (NP_0017571)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595921

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Antigen:
AIRE

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Aire

Gene Alias:
Aire, AIRE protein, AIRE1, APECED, APECED protein, APECED protein homolog, APS1, APSI, Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein, autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein homolog, Autoimmune regulator, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy), autoimmune regulator AIRE1a, LOW QUALITY PROTEIN: autoimmune regulator, OTTHUMP00000109529, PGA1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11634, 294328, 326

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1.57 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
O43918, Q9Z0E3

Gene Symbols:
Aire

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 30-130 of human AIRE (NP_0003741)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG