926027
NanoFabTX™-DOTAP Lipid Mix
for synthesis of cationic (DOTAP) liposomes
Manufacturer: Sigma Aldrich
Synonym(S): Drug delivery, LNP, Microfluidics, NanoFab reagent kit, Nanoformulation, Nanoparticle
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 50 MG | 926027-50-MG | In Stock | ₹ 27,450.00 |
926027 - 50 MG
In Stock
Quantity
1
Base Price: ₹ 27,450.00
GST (18%): ₹ 4,941.00
Total Price: ₹ 32,391.00
Quality Level
100
storage temp.
−20°C
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Description
- General description: NanoFabTx™-DOTAP Lipid Mix includes reagents and optimized protocols with step-by-step instructions for synthesizing cationic liposomes for drug delivery research applications. The modification of liposomes with the cationic lipid, DOTAP, have numerous advantages such as their large-DNA incorporation, high transfection efficiency, and low toxicity. Liposome-based formulations are widely used for drug delivery applications and enable improved therapeutic efficacy of a range of drug types including small molecules, nucleic acids, proteins, and peptides. Comprehensive protocols for liposome synthesis are included:A lipid film hydration and extrusion protocol. A microfluidics protocol using commercial platforms or syringe pumps. The microfluidics protocol included with this product uses NanoFabTx™ device kits (911593). These kits come with the microfluidics chips, fittings, and tubing required to get started with microfluidics-based synthesis (compatible microfluidics system or syringe pump required).
- Application: NanoFabTx™-DOTAP Lipid Mix is a ready-to-use nanoformulation blend for the synthesis of cationic DOTAP-functionalized liposomes. This kit enables users to encapsulate a wide variety of therapeutic drug molecules for targeted or extended drug delivery without the need for lengthy trial-and-error optimization. NanoFabTx™ kits provide an easy-to-use toolkit for encapsulating a variety of therapeutics in nanoparticles, microparticles, or liposomes. Drug encapsulated particles synthesized with the NanoFabTx™ kits are suitable for biomedical research applications such as oncology, immuno-oncology, gene delivery, and vaccine delivery.
- Features and Benefits: A ready-to-use nanoformulation blend for the synthesis of cationic liposomes Step-by-step protocols (extrusion or microfluidic) developed and tested by our formulation scientistsFlexible synthesis tools to create uniform and reproducible liposomesOptimized to make liposomes around 100 nm with low polydispersityDOTAP surface-functionalized allows for targeting ligand conjugation to enable targeted drug delivery
- Legal Information: NANOFABTX is a trademark of Sigma-Aldrich Co. LLC
SAFETY INFORMATION
WGK
WGK 3
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Quality Level: 100
storage temp.: −20°C
Quality Level:
100
storage temp.:
−20°C
Quality Level: 100
storage temp.: __
Quality Level:
100
storage temp.:
__
Quality Level: 100
storage temp.: __
Quality Level:
100
storage temp.:
__
Quality Level: 100
storage temp.: __
Quality Level:
100
storage temp.:
__