NanoFabTx™ for gene delivery

Description

• General description: Azide lipid mix for gene delivery and targeted delivery
• Application: With the NanoFabTx™ gene delivery azide lipid mix, researchers can simplify their drug development workflow. The ready to use mix enables the screening of different drug modalities such as oligonucleotides, nucleic acids (mRNA, DNA, siRNA), and vaccines without the need to develop new drug delivery formulations from scratch, ultimately speeding up the time it takes for innovative therapeutics to go from the bench to the clinic. The azide-functionalized surface of the LNP can be used to conjugate to DBCO or alkyne-modified biomolecules for active targeting applications including targeting immune cells, cancer cells, or designated tissues throughout the body. This ready to use lipid mix can be used to screen a variety of different targeting moieties to determine what works best for your application or therapeutic. The lipid mix has also been carefully curated specifically for enhanced gene delivery.
• Features and Benefits: A ready-to-use nanoformulation lipid blend to synthesize azide-functionalized lipid nanoparticles Step-by-step protocols developed and tested by our formulation scientists Flexible synthesis tool to create uniform and reproducible lipid nanoparticlesOptimized to make lipid nanoparticles around 100 nm with low polydispersityOptimized lipid blend for DBCO-modified protein or antibody conjugation Optimized lipid blend for azide-functionalized lipid nanoparticles for mRNA encapsulation For more information, please refer to the protocol under the document section of this page.
• Legal Information: NanoFabTx is a trademark of Sigma-Aldrich Co. LLC